NurseHub HESI® A2 Practice Test and Study Guide Review

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Practice flashcards covering Science (Anatomy & Physiology, Biology, Chemistry), Math, Grammar, and Vocabulary based on the NurseHub HESI® A2 practice exam and study rationales.

Last updated 1:03 AM on 6/20/26
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84 Terms

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HESI® A2

The Health Education Systems, Inc. Admission Assessment, a computerized exam used for journey into nursing school.

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ProctorU

An online service through which some schools offer the HESI® A2 exam online.

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Sagittal plane

A vertical plane that runs from the front to the back, dividing the body into left and right sides.

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Coronal plane

A vertical plane that divides the body into front (anterior) and back (posterior) sections; also called a frontal plane.

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Transverse plane

A horizontal plane that divides the body into upper (superior) and lower (inferior) parts.

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Distal

An anatomical direction meaning further away from the trunk of the body.

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Proximal

An anatomical direction meaning closer to the trunk of the body.

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Medial

An anatomical direction meaning closer to the midline of the body.

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Lateral

An anatomical direction meaning further away from the midline of the body; situated at or proceeding from the side.

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Cardiac muscles

Branched, striated muscles with a single nucleus found in the heart; they are not under voluntary control.

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Smooth muscles

Spindle-shaped, nonstriated, involuntary muscles with a single nucleus found in hollow organs.

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Skeletal muscle

Striated multinucleated cylindrical fibers attached to bones moves the body under voluntary control.

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Compact bone

The harder, outer shell of the bone composed of Haversian canals surrounded by concentric rings of lamellae.

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Cancellous bone

The inner meshwork of spongy tissue (trabeculae) found at the core of vertebral bones and ends of long bones; also called spongy bone.

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Neurons

Excitable nervous tissues typically covered by a myelin sheath with a cell body, an axon, and dendrites.

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Neuroglia

Non-excitable nervous tissue, such as Astrocytes and Schwann cells, that support the neurons; also called glial cells.

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Diaphysis

The shaft of a long bone.

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Epiphyses

The two ends of a long bone.

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Adduction

A body movement that pulls a structure towards the midline.

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Abduction

A body movement that pulls a structure away from the midline.

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Flexion

A body movement that reduces the angle at a joint.

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Supination

A rotation of the forearm so that the palm faces anteriorly (towards the front).

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Sarcomere

The basic contractile unit of a muscle, composed of actin and myosin filaments.

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Actin

A thin protein filament in a muscle fiber covered in troponin.

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Myosin

A thick protein filament in a muscle fiber that binds to actin to cause contraction.

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Central nervous system

One of the two main parts of the nervous system, comprised of the brain and spinal cord.

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Peripheral nervous system

A part of the nervous system comprising the cranial nerves, spinal nerves, peripheral nerves, and ganglia.

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Autonomic nervous system

The involuntary part of the peripheral nervous system that innervates smooth muscle, cardiac muscle, glands, and viscera.

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Somatic nervous system

The voluntary part of the peripheral nervous system that innervates skeletal muscle.

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Pancreas

An organ in the abdomen that produces digestive enzymes and the hormones glucagon and insulin.

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Hypothalamus

The control center for the endocrine system that tells the pituitary gland what hormones to make and maintains homeostasis.

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Pituitary gland

The "master endocrine gland" that produces several hormones regulating the activities of other endocrine glands.

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Erythropoiesis

The process of producing red blood cells, which occurs in the bone marrow.

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Erythropoietin

A hormone released by the kidneys when they detect low blood oxygen, signaling the bone marrow to produce more erythrocytes.

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EKG / ECG

An electrocardiogram that records the electrical activity of the heart to check for various conditions.

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Mastication

The process by which teeth break down food particles in the oral cavity.

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Chyme

Partially digested food mixed with gastric juice produced in the stomach.

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Nephron

The functional unit of the kidney, each made up of a glomerulus and a tubule.

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Dermis

The thickest, vascular layer of the skin containing capillaries necessary for thermoregulation.

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Synapse

A specialized junction from which nerve impulses pass from one neuron to the next.

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Placebo

A pill or treatment with no therapeutic value administered to prevent subjects from knowing if they are receiving real drug.

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Specific heat

The amount of heat needed to raise the temperature of one gram of a substance by one degree Celsius.

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Enzymes

Proteins that catalyze or accelerate different cellular reactions and processes.

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Ribosomes

Organelles responsible for protein synthesis by reading RNA and translating genetic instructions.

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Mitochondria

The powerhouse of eukaryotic cells and the site of cellular respiration where ATP is produced.

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Lysosomes

The digestive system of the cell containing hydrolytic enzymes that break down proteins, fats, sugars, and nucleic acids.

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Vacuoles

Membrane-enclosed structures that provide storage for the cell, waste disposal, or protection.

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Active transport

The movement of material across a membrane against the concentration gradient (from low to high concentration), requiring energy.

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Passive transport

The movement of substances from an area of high concentration to low concentration, such as diffusion or osmosis.

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Cellular respiration

A metabolic pathway consisting of glycolysis, the citric acid cycle, and oxidative phosphorylation that breaks down glucose to produce ATP.

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Photosynthesis

An anabolic process where plants use carbon dioxide, water, and light energy to produce glucose (C6H12O6C_6H_{12}O_6) and oxygen (O2O_2).

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Glycolysis

The first step in the breakdown of glucose to extract energy, producing two three-carbon molecules called pyruvates.

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Fermentation

An anaerobic pathway that breaks down glucose to extract energy in the absence of oxygen, producing alcohol or lactic acid.

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Mitosis

Nuclear cell division in eukaryotic cells where a single parent cell divides into two identical daughter cells.

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Meiosis

A type of cell division resulting in four unique daughter cells with half the number of chromosomes of the parent cell, forming gametes.

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Genotype

The genetic makeup of an individual organism, often represented as a combination of alleles (e.g., BBBB, BbBb, or bbbb).

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Phenotype

The set of observable characteristics of an individual resulting from its genetic makeup (e.g., brown hair).

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Principal

A noun referring to the person of highest authority in an organization.

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Principle

A noun referring to a rule, tenet, or basic truth.

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Accept

A verb meaning to receive or approve of something.

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Except

A preposition meaning excluding or to leave out.

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Misplaced modifier

Words or phrases not located properly in relation to the words they modify or describe.

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Complex sentence

A sentence containing an independent clause and at least one dependent clause.

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Compound sentence

A sentence with at least two independent clauses joined by a semicolon or a comma and a conjunction.

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Simple sentence

A sentence consisting of only one clause with a single subject and predicate.

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Anion

A negatively charged atom that has more electrons than protons.

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Cation

A positively charged atom that has more protons than electrons.

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Isotope

Atoms with the same number of protons and electrons but a different number of neutrons.

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Sublimation

The phase transition where a solid (like ice) transforms directly into a gas (like steam) without becoming a liquid.

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Catalyst

A substance that increases the rate of a chemical reaction by lowering the activation energy without being consumed.

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OIL RIG

A mnemonic for redox reactions: Oxidation Is Loss, Reduction Is Gain of electrons.

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Half-life

The amount of time it takes for half of a radioactive substance to decay.

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Abrupt

Sudden or unexpected.

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Febrile

Pertaining to or marked by fever.

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Languid

Lacking energy, or causing a lack of energy or enthusiasm.

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Cicatrix

New tissue that forms over a wound and later contracts into a scar.

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Palliative

A treatment that reduces pain without curing the cause of the pain.

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Endogenous

Found or coming from within something, such as a system or a person’s body or mind.

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Vertigo

A sensation of whirling and loss of balance.

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Staunch

A verb meaning to stop something from happening, especially to stop the flow of blood from a wound.

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Occluded

To close, shut, or stop up, such as blocked circulation.

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Predicate nominative

A noun or pronoun that follows a linking verb and renames or explains the subject.

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Direct object

A word or phrase representing a person or thing receiving the action done by a verb.

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Indirect object

The person or thing that is receiving the direct object or the action of the verb.