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Homeostasis
Maintenance of a stable internal environment despite external changes
Dynamic steady state
Condition where the body maintains balance through constant adjustments, not perfect equilibrium
Set point
Target value the body tries to maintain for a regulated variable
Negative feedback
A response that counteracts a change to return a variable to its set point
Positive feedback
A response that amplifies a change, increasing the original stimulus
Thermoregulation
Maintenance of stable internal body temperature
Endotherm
Organism that regulates internal body temperature using internal mechanisms (warm-blooded)
Ectotherm
Organism whose body temperature changes with environmental temperature (cold-blooded)
Hypothalamus
Brain region that regulates temperature, hunger, thirst, and circadian rhythm
Effector
Organ or cell that carries out the response in a feedback loop
Input
Signal that carries information about a variable to the control center
Integration
Process where the brain compares input to a set point
Output
Signal sent from control center to effectors
Vasodilation
Widening of blood vessels to release heat
Vasoconstriction
Narrowing of blood vessels to conserve heat
Shivering
Muscle contractions that generate heat
Sweating
Release of fluid that cools the body through evaporation
Insulin
Hormone that lowers blood glucose by promoting glucose uptake into cells
Glucagon
Hormone that raises blood glucose by signaling liver to release glucose
Pancreas
Organ that produces insulin and glucagon
Positive feedback in childbirth
Process where contractions increase hormone release, which increases contractions
Negative feedback in temperature
Body responses that return temperature to normal when it rises or falls
ATP
Adenosine triphosphate, universal energy currency of the cell
Adenine
Nitrogenous base found in ATP, DNA, and RNA
Ribose
5-carbon sugar component of ATP
Phosphate group
Functional group containing phosphorus and oxygen that stores energy in ATP
ATP structure
Adenine + ribose + 3 phosphate groups
AMP
Adenosine monophosphate (1 phosphate)
ADP
Adenosine diphosphate (2 phosphates)
ATP hydrolysis
Breakdown of ATP into ADP + Pi releasing energy
Pi
Inorganic phosphate released when ATP is broken down
Potential energy in ATP
Energy stored in bonds between phosphate groups
ATP synthase
Enzyme that produces ATP using proton gradient energy
Chemiosmosis
Movement of H⁺ ions through ATP synthase to generate ATP
Proton gradient
Difference in H⁺ concentration across a membrane
Electron transport chain
Series of proteins that transfer electrons and pump protons
Cellular respiration
Process that breaks down glucose to produce ATP
Aerobic respiration
Cellular respiration that requires oxygen
Anaerobic respiration
Energy production without oxygen, less ATP produced
Glycolysis
Breakdown of glucose into pyruvate in the cytoplasm
Cytoplasm
Location where glycolysis occurs
Pyruvate
3-carbon product of glycolysis
Net ATP from glycolysis
2 ATP produced per glucose
NADH
Electron carrier that stores high-energy electrons
Pyruvate oxidation
Conversion of pyruvate into acetyl-CoA in mitochondria
Mitochondrial matrix
Site of pyruvate oxidation and Krebs cycle
Acetyl-CoA
2-carbon molecule that enters Krebs cycle
CO2 release
Waste product formed during pyruvate oxidation and Krebs cycle
Krebs cycle
Series of reactions that produces electron carriers and CO2
Citric acid cycle
Another name for Krebs cycle
FADH2
Electron carrier produced in Krebs cycle
Krebs cycle ATP yield
2 ATP per glucose
NADH from Krebs cycle
6 NADH per glucose
FADH2 from Krebs cycle
2 FADH2 per glucose
Oxidative phosphorylation
ATP production using ETC and chemiosmosis
Inner mitochondrial membrane
Location of electron transport chain
Oxygen role in respiration
Final electron acceptor forming water
Water formation
Oxygen combines with electrons and H⁺ to form H2O
ATP yield total
About 30–38 ATP per glucose depending on efficiency
Glycolysis yield
2 ATP per glucose
Krebs cycle yield
2 ATP per glucose
ETC ATP yield
Up to 32 ATP per glucose
Fermentation
Anaerobic process that allows glycolysis to continue without oxygen
Low oxygen condition
Triggers fermentation instead of aerobic respiration
Energy efficiency
Aerobic respiration produces more ATP than anaerobic processes
Glucose
Primary fuel molecule used in cellular respiration
Cellular respiration equation
Glucose + oxygen → CO2 + water + ATP
Active transport
Movement of substances against gradient using ATP
Sodium potassium pump
Protein that uses ATP to pump Na+ out and K+ into cells
Neuron function
Relies heavily on ATP for ion gradients
Muscle contraction
Process powered by ATP and actin-myosin interaction
Myosin
Motor protein that interacts with actin during contraction
Actin
Protein filament involved in muscle contraction
Protein synthesis
Process of building proteins using amino acids
tRNA
Transfers amino acids to ribosome during protein synthesis
ATP in protein synthesis
Provides energy to attach amino acids
LUCA
Last Universal Common Ancestor of all life
Universal molecules
ATP, DNA, RNA, proteins found in all life forms
Photosynthesis
Process that converts CO2 and water into glucose using light energy
Equation of photosynthesis
CO2 + H2O + light → glucose + O2
Chloroplast
Organelle where photosynthesis occurs
Thylakoid membrane
Site of light-dependent reactions
Stroma
Site of Calvin cycle in chloroplast
Grana
Stacks of thylakoids in chloroplast
Chlorophyll
Pigment that absorbs red and blue light, reflects green
Pigments
Molecules that absorb specific wavelengths of light
Absorption spectrum
Range of light wavelengths absorbed by pigments
Carotenoids
Accessory pigments that absorb additional wavelengths
Light-dependent reactions
Stage of photosynthesis producing ATP, NADPH, and oxygen
Photosystem II
Complex that splits water and releases electrons
Photolysis
Splitting of water into oxygen, protons, and electrons
Electron transport chain in photosynthesis
Transfers electrons and pumps protons in thylakoid membrane
Photosystem I
Re-energizes electrons to produce NADPH
NADPH
Electron carrier used in Calvin cycle
Calvin cycle
Light-independent reactions that produce G3P from CO2
Carbon fixation
Process where CO2 is attached to RuBP
RuBP
5-carbon molecule that binds CO2 in Calvin cycle
Rubisco
Enzyme that catalyzes carbon fixation
G3P
3-carbon molecule used to form glucose
Reduction phase
ATP and NADPH convert 3-PGA into G3P