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drugs that turn body fluid brown
entacapone, levodopa, methyldopa
drugs that turn body fluid brown/yellow
nitrofurantoin
drugs that turn body fluid black/green
iron (stool)
drugs that turn body fluid orange/yellow
sulfasalazine
drugs that turn body fluid green
propofol
drugs that turn body fluid redd-orange
rifampin, phenazopyridine,
drugs that turn body fluid red
anthracyclines
drugs that turn body fluid blue
methylene blue, mitoxantrone,
drugs that turn body fluid blue-gray
amiodarone
what is aloe used for
its soothing effects in sunburn and psoriasis
what is tea tree oil
acne
what is lysine used for
cold sore and herpes prevention and treatment
what is biotin used for
hair loss and brittle nails
topical vitamin d is used for
diaper rash and psoriasis
what is the primary determinant of acne and other things that contribute
androgen is the primary dertminant
bacteria like cutibacterium and thensebaceous gland also contribute
things for treating acne
benzoyl peroxide, retinoids, antibiotics,salicylic acid, isotretinoin
how do retinoids work
they are vitamin A derivatives that work by reducing cohesion of follicular epithileal cells. they are teratogenic and must be avoided in pregnanct or breast feeding
how are retinoids applied
apply nightly in a pea-sized amount
how long does retinoid take to work
4-12 weeks and they worsen acne inititally
what tests are required when taking isotretinoin
Liver, lipid, pregnancy
what are some other acne treatments
oral contraceptives pills, azelaic acid, clascoterone
first line treatnent for mild acne
topicals: BPO or retinoid or combination
alternative: add topical retinoid or BPO, switch to another retinoid or topical dapsone
first line treatment for moderate acne
topical: combination or PO antibiotic + BPO + topical retinoid (± topical antibiotic)
alternative: other combination, switch PO antibiotic, add combined OCP or spironolactone (females) or PO isotretinoin
first line treatment for severe acne
topicals combination + PO antibiotic or PO isotretinoin
topical retinoids notes
topcal retinoids should be avoided in pregnac
tretinoin has slower relase and less skin irritation
tretinoin brand names
atralin, renova, retin-a, retin-a micro, altreno
benzoyl peroxide counseling
can bleach clothing
what can occur with clascoterone
HPA Axis suppression
avoid dapsone gel in
G6PD deficiency
isotretinoin boxed warning
birth defects have been documented
can only be dispensed by a pharmacy registered with the REMS (IPLEDGE PROGRAM, 1 month Rx at a time
isotretinoin notes
patients who can get pregnant must sign informed consent form about birth defects
must have 2 negative pregnancy tests prior to starting
do not use vitamin a supplements , tetracyclines, progestin only contraceptives, st johns wort
isotretinoin safety and counseling
dry skin, lips, dry eyes/eye irritation
2 forms of birth control are required (cannot use a progestin only pill)
oral antibiotics (doxycyline and minocycline safety and counseling
photosensitivity, fetal harm, discoloration in teeth
how is abreva used in cold sores
apply 5x daily at first sign of outbreak
how to use zovirax cream
apply 5x a day for 4 days
what is dandruff
causes white itchy flakes of dead skin cells in the hair
otc drug for dandruff
ketoconazole 1% shampoo (nizoral a-d), selenium sulfide, pyrithione zinc (head and shoulders), coal for shampoos (T/Gel)
rx for dandruff
ketoconazole 2% shampoo
drugs that cause alopecia
chemotherapeutic agents
valproate acid
lamotrigine
tacrolimus
what kinds of deficiencies contribute to hair loss
biotin, zinc, selenium, and vitamin d deficiency
drugs used for alopecia
finasteride (propecia) tablet
minoxidil topicals
bimatoprost
finasteride dosing
1 mg daily; can take >3 months to begin to see effect
finasteride contraindication
pregnancy
finasteride warning
hazardous drug for females of childbearing potential
finasteride moa
inhibits 5 alpha reductase type 2
bimatoprost is used for
for thinning eyelashes (hypotrichosis)
do not use bimatoprost with
prostaglandin analogs used for glaucoma (IOP may increase)
how is bimatoprost applied
nightly with applicator brushto skin at the base of the upper eyelashes
diaper rash prevention
petrolatum ointment
petrolatum with zinc oxide (a desicant)
diaper rash treatment
nystatin if yeast is thought to be involved
how does eczema appear
itchy, red, dry skin rashes and may turn into crusty, scaly sores
what reduces severity of eczema
hydration and mositurizers
what reduces utching in eczema
antihistamines
what are treatment options in eczema
otc: aquaphor, eucerin
topical steroids, and topical calcineurin inhibitors
topical PDE4 inhibitors
interleukin receptor antagonists
counseling for topical products in eczema
wash hands after application
topical calcineurin inhibitors counseling
do not use in children age <2 associated with lymphoma and cancer
athlete’s foot symptoms
itching, peeling, redness, mild burning
athlete’s foot is most common in
people that use public pools, showers and locker rooms
what is a ringworm on the scalp
tinea capitis
where does jock itch affect
genitas, inner thighs, and buttocks
the rash is red,itchy and can be ring haped
topical candida infections cause rashes where
groins, armpits, or anywhere the skin folds
drugs used in fingal infectiond
terbinafine
butenafine
clotrimazole
miconazole
tolnaftate
undecyclenic acid
terbinafine brand name
lamisil AT
butenafine brand name
lotrimin ultra
miconazole brand name
lotrimin AF
tolnaftate
tinactin
betamathasone/clotrimazole brand name
lotrisone
athletes food counseling
if infection is on the foot, avoid walking barefoot to prevent spreading
ring worm counseling
apply medication 1-2 inches beyond the rash
how long should topicals in fungal rash be used
2-4weeks
what is onychomycosis
a fungal infection of the nail
topical drugs in nail infections
not potent enough
what is used to treat fungal nail infections (2)
itraconazole and terbinafine
when is pulse therapy used in nail infections
used to reduce cost but may not be as effective
what test is used to diagnose fungal nail infections
20% potassium hydroxide smear
itraconazole boxed warning
avoid use in heart failure
itra and terbinafine are both hepatotoxic
in vaginal infections pregnant patients should
consult their physician. longer duration may be required (7-10 days)
a pH >4.5 is consistent with
bacterial vaginosis ot trichomoniasis infextion
how to test vaginal pH
OTC test kits
if more than 4 vaginal infections ina year or symptoms recur within 2 months
refer to physician to rule out other causes
how to treat mild - moderate infrequent vaginal infections
1, 3,or 7 day treatment with vaginal cream, ointment, tablet or suppository
OTC topicals for vaginal infectiond
clotrimazole
miconazole (monistat 3)
vaginal infection rx topicals
butoconazole (gynazole-1)
vaginal infections rx oral
fluconazole 150 mg PO X1
hemerrhoids drugs and how they work
psyllium: increasing fiber intake can reduce straining
phenylephrine: vasoconstrictor that shrinks the hemerrhoid and reduces burning and itching
hydrocortisone (anusol- HC): reduce itching and inflammation
witch hazek ( tucks medicated cooling pads): mild astringent that can relieve mild itching
what is used to treat scabies
permethrin cream 5%
what is used to treat lice
topical OTC drugs are first line permethrin lotion 1%, and pyrethrina
what is the scientific name for lice
pediculus humanus capitis
what shoukd you do after treatment of lice
use a nit comb to remove nits and lice every 2-3 days
malathion lotion 0.5% causes
skin irritation and is flammable
most lice products require
re-treatment
pinworm occurs mostly in ? and presents as ?
occurs mostly in children and presents as anal itching
what drugs are used for pinworm infections
mebendazole, pyrantel pamoate
what is the tape test
used in pinworm infection to identify eggs; sticl a piece of tape around the anus in the morning
how many tape tests does it take to identify eggs in pinworm
it can take up to three tape tests to idientify eggs
when are albendazole and mebendazole used in pinworm
systemic worm infections
what do mebendazole cause
headache, nausea, and hepatotoxic
permethrin 1% lotion brand name
Nix
pyrethrin/piperonyl butoxide brand name
RID
what is the most common method of debridement in wounds
enzymatic debridement which is done with the application of collagenase ointment