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Evolution
Descent with modification where populations change over time through heritable variation and differential reproduction
Darwin’s argument
Heritable variation leads to differential reproduction which changes populations and can lead to speciation
Natural selection
Process where favorable heritable traits increase in frequency because they improve survival or reproduction
Conditions for natural selection
Variation exists; variation is heritable; variation affects survival or reproduction
Adaptation
Trait that increases fitness and becomes more common in a population over generations
Adaptive evolution
Population becomes better suited to environment as advantageous traits accumulate
Biological fitness
Ability to survive and reproduce relative to others in a population
Adaptive radiation
Formation of multiple species from a common ancestor due to adaptation to different environments
Microevolution
Change in genetic structure of a population across generations
Measurement of microevolution
Changes in allele and genotype frequencies
Hardy-Weinberg equilibrium
Model where no evolution occurs and genotype frequencies remain constant
Purpose of Hardy-Weinberg
Serves as null hypothesis for detecting evolution
Deviation from Hardy-Weinberg
Indicates that evolutionary forces are acting
Allele
Different version of a gene with altered sequence or regulation
Origin of alleles
Mutation or genetic exchange
Mutation
Ultimate source of all genetic variation
Relationship of mutation and selection
Mutation creates variation and selection acts on it
Phenotypic vs molecular measurement
Evolution measured by traits or DNA sequencing
Artificial selection
Human-directed breeding for desired traits
Difference from natural selection
Artificial selection is human-controlled while natural selection is environment-driven
Result of artificial selection
Organisms often differ greatly from wild ancestors
Evidence of microevolution
Direct observation such as antibiotic resistance in bacteria
MRSA example
Resistant bacteria survive antibiotics and reproduce more when antibiotics are present
Trade-off in MRSA
Resistance may be disadvantageous when antibiotic is absent
Speciation
Formation of new species due to reproductive isolation
Species definition
Populations that can interbreed and produce viable offspring
Mechanism of speciation
Subpopulations stop interbreeding and accumulate genetic differences
Role of variation in speciation
Differences in traits can drive reproductive isolation
Host switching
Evolution of pathogens to infect new host species
Examples of host switching
Measles from cattle; influenza from birds; HIV from chimpanzees; COVID-19 likely from bats
Importance of speciation
Explains origin of diseases and biodiversity
Macroevolution
Large-scale patterns of evolution including history of life
Fossil
Preserved remains or traces of organisms from the past
Fossil record
Worldwide distribution of fossils documenting evolutionary history
Key fossil insight
Most fossils differ from living species showing change over time
Strata
Layers of sedimentary rock representing chronological deposition
Law of succession
Fossils appear in predictable order in rock layers globally
Biogeographic fossil pattern
Living organisms resemble fossils from the same region
Transitional forms
Fossils showing intermediate stages between ancestral and derived species
Significance of transitional fossils
Provide direct evidence of evolutionary change
Example of macroevolution
Whale ancestors evolved from land mammals related to even-toed ungulates
Common ancestry
All life forms share a common evolutionary origin
Homology
Similarity due to shared ancestry
Homologous structures
Same ancestor but different function
Convergent evolution
Independent evolution of similar traits in different lineages
Analogous structures
Same function but different evolutionary origin
Vestigial structures
Remnants of ancestral features with little or no current function
Significance of vestigial structures
Evidence of evolutionary history
Molecular homology
Similarities in DNA or genes indicating common ancestry
Universal genetic code
Evidence that all organisms share a common origin
Pseudogenes
Nonfunctional gene copies indicating evolutionary relationships
Evo-devo
Study of how development influences evolutionary change
Differential gene expression
Different genes activated during development to produce structures
Regulatory genes
Control timing
Impact of regulatory changes
Small genetic changes can produce large morphological differences
Cell-cell interactions
Critical for proper development
Regulatory genes controlling body plan and limb development
Limb development example
Hox gene expression patterns determine whether limbs or ribs form
Snake limb loss
Overlapping Hox gene expression prevents forelimb formation
Why evolution is controversial
Microevolution widely accepted but macroevolution challenges beliefs about human origins
Correct phrasing of human evolution
Humans share a common ancestor with monkeys rather than evolved directly from them
Scientific principle
Science does not begin with conclusions but tests evidence
Biodiversity
Variety of life at multiple levels
Genetic diversity
Variation in alleles within populations important for adaptability
Species diversity
Combination of species richness and evenness
Habitat diversity
Variety of environments supporting different species
Biogeography
Study of species distribution across space
Factors affecting species range
Climate
Human impact on biogeography
Introduction of invasive species alters distributions
Assemblage
Group of species living together in a community
Museum collections
Allow analysis of historical biodiversity and environmental change
Species interactions
Relationships between species affecting survival
Competition
Organisms compete for limited resources
Intraspecific competition
Competition within the same species
Interspecific competition
Competition between different species
Exploitative competition
Indirect competition through resource use
Interference competition
Direct interaction blocking access to resources
Mutualism
Both species benefit
Commensalism
One benefits while the other is unaffected
Amensalism
One harmed while the other unaffected
Predation
One organism consumes another
Parasitism
One organism benefits at the expense of another
de Wit replacement series
Experimental method comparing species growth in monoculture vs mixed culture
Monoculture
Growth of a single species alone
Mixed culture
Growth of multiple species together
Destructive sampling
Measuring organisms by removing them from experiment
Independent variable
Factor manipulated in an experiment
Dependent variable
Measured outcome
Positive control
Condition expected to produce a known effect
Negative control
Condition expected to produce no effect
Null hypothesis
Prediction that there is no difference between groups
Mean
Average of data
Variance
Measure of spread of data
Standard deviation
Degree of variation around the mean
Normal curve
Bell-shaped distribution of data
T-score
Statistic comparing difference between means relative to variation
p-value
Probability that observed results are due to chance
Significant result
Low p-value indicating unlikely due to chance
Interpretation of significance
Rejects null hypothesis but does not prove causation