APhA Final Exam

Which of the following is true for live attenuated vaccines?

They must replicate to stimulate an immune response.

Vaccines should be delayed for which of the following patients?

A patient with moderate to severe acute illness that requires additional care

Which of the following statements is true about risks associated with vaccines and vaccine-preventable diseases?

International travelers import many cases of vaccine-preventable diseases into the United States each year.

Tasha is a 26-year-old woman with rheumatoid arthritis who is treated with immunosuppressive therapy. Which of the following vaccines should be avoided for Tasha?

MMR

At what age should an immunocompromised patient receive the recombinant zoster vaccine (RZV)?

19 years

Which of the following is a provider factor associated with low vaccination rates in adults?

Lack of time to focus on preventive services

The majority of cases of vasovagal syncope occur within how many minutes following vaccination?

15 minutes

John is 42 and was diagnosed with HIV 2 months ago. He received one dose of MenACWY at that time and is now getting his 2nd dose. Which of the following would be an appropriate recommendation for MenACWY vaccination for John?

Revaccinate with MenACWY every 5 years

What is the concern with giving inactivated vaccines to patients who are immunocompromised?

They may not be as effective.

What could potentially happen if an intramuscular vaccine intended for the deltoid muscle is administered too high?

Severe shoulder pain and injury

Which of the following sections is new to the CDC immunization schedules?

Addendum

Mina is 2 years old and just received her first dose of the influenza vaccine. When should she return for her next dose?

4 weeks

Which of the following is the routine schedule for vaccinating adolescents with MenACWY?

One dose at age 11 to 12 years, followed by a booster dose at age 16 years

Which of the following vaccines is recommended for healthy adolescents and adults ages 16 through 23 years based on shared clinical decision-making?

Meningococcal B

How many doses of the 15-valent pneumococcal conjugate vaccine (PCV15) are needed to complete the routine series in children beginning at 2 months of age?

4

For individuals who are immunocompetent, at what ages can the 2-dose HPV series be given?

9 through 14 years

Which of the following tetanus toxoid-containing vaccines would be appropriate for a 15-month old child?

DTaP

Larry is 68 years old and has a new grandbaby on the way. He received a Td vaccine approximately 13 years ago. He doesn't know if he received any tetanus toxoid-containing vaccines prior to that. Which of the following tetanus toxoid-containing vaccines would be most appropriate to recommend?

Tdap

Which of the following patients would be an appropriate candidate for the adjuvanted influenza vaccine (aIIV4)?

A 72 year-old woman with COPD

Mariah is a 15-year-old high school student with no chronic medical conditions. She is at the pharmacy to receive her COVID-19 booster and influenza vaccines. She completed the primary series of DTaP, IPV, PCV, Hib, and MMR. She received the complete series of hepatitis A and hepatitis B vaccines before entering high school. What other vaccines does she need?

Varicella, Tdap, HPV, MenACWY

A patient who reports an allergy to eggs that has resulted in hives may receive which of the following influenza vaccines?

Any influenza vaccine

Kevin is 11 years old with no chronic medical conditions who comes to your pharmacy on September 30 for his flu shot. He completed the primary series of DTaP, IPV, hepatitis A, hepatitis B, and Hib, and had a physician-diagnosed case of chickenpox at 2 years of age. Which of the following would also be appropriate to recommend for Kevin today?

Tdap, HPV, MenACWY, MMR, 2024-25 COVID-19

Which of the following is a contraindication that is applied to all vaccines?

Severe allergic reaction to a vaccine component following a previous dose

Which of the following is a requirement of the Occupational Safety and Health Administration (OSHA) bloodborne pathogens standard?

All employees with potential bloodborne pathogen exposure must receive OSHA bloodborne pathogen training every year

Michael, a 47-year-old health care worker, has no laboratory evidence of immunity to measles or mumps and cannot confirm that he had either disease. How many doses of MMR vaccine should Michael receive?

Two doses of MMR

Which type of vaccine mediates immunity based solely on B cells?

Pure polysaccharide

How do vaccines elicit an immune response?

They contain antigens that stimulate the production of antibodies.

Which of the following is true for the recommended catch-up immunization schedule?

It is for children who start late or are more than 1 month behind on immunizations

What is the minimum interval between doses one and two of the hepatitis A vaccine?

6 months

Which of the following vaccines should be administered to boys and young men aged 9 through 26 years to reduce their likelihood of acquiring genital warts?

HPV

What are immunization coalitions?

Groups that foster collaboration among stakeholders within a community as a means to increase immunization rates

Adult RSV vaccine is recommended for which of the following individuals?

78 year old woman without any chronic conditions

If a patient is experiencing anaphylaxis and requires epinephrine, what is the dose and route of administration using a 1:1000 (1mg/mL) product?

0.01 mg/kg IM in the anterolateral aspect of the thigh

Which of the following represents an opportunity for pharmacists to collaborate with other providers?

Offer to administer the remaining doses in a vaccine series

Which of the following is the minimum needle length recommended for intramuscular administration of the influenza vaccine to an adult man weighing 265 lbs?

1½ inches

What might happen if the recommended interval between vaccine doses in a series is decreased?

It may interfere with antibody response and reduce vaccine effectiveness.

David is 58 years old. He received an inactivated influenza vaccine 5 days ago at a mass clinic run by the health department. He is now at your pharmacy and you determine he should get his herpes zoster and Tdap vaccines. How should you proceed with administering these vaccines?

Give both Tdap and the herpes zoster vaccines today.

Which of the following best describes how to administer Tdap vaccine to an adult woman who weighs 195 lbs?

Intramuscularly at a 90-degree angle in the deltoid muscle

Which of the following is the most appropriate injection site for administering the hepatitis B vaccine to an adult patient?

Deltoid muscle

Which of the following would be an appropriate needle size and length for administering varicella vaccine to 5 year-old child?

25 gauge; 5/8 inch

If a patient needs two inactivated vaccines, but they were not administered on the same day, how much time must the patient wait between vaccine doses?

There is no minimum interval of time

What type of immunity occurs when a person receives antibodies from another source?

Passive

At what ages is the first dose of the rotavirus vaccine recommended?

2 months

ACIP recommends PCV21 as an option for which of the following individuals?

45 year old man with diabetes and no previous PCV vaccine

How should Tdap be administered to pregnant women?

Administer one dose with each pregnancy in the third trimester