Top 300 Hormonal/Immunological

What is the brand name of Anastrazole?

Arimidex

What is the drug class of Anastrazole?

Antineoplastic agent/ Aromatase Inhibitor

What is the normal adult dose of Anastrazole?

PO: 1 mg once daily

What is the BBW for Anastrazole?

None

What is the brand name of Bimatoprost?

Lumigan; Latisse

What is the drug class of Bimatoprost?

Antiglaucoma, Prostaglandin

What is the normal adult dose of Bimatoprost?

Ocular: Instill 1 drop into affected eye(s) every evening

What is the BBW for Bimatoprost?

None

What is the brand name of Conjugated Estrogens?

Premarin

What is the drug class of Conjugated Estrogens?

Hormone replacement, Estrogen derivative

What is the normal adult dose of Conjugated Estrogens?

- PO: 0.3-0.625 mg daily or on a cycle, higher doses can be used for other conditions

- IM, IV: 25 mg, may repeat in 6-12 hours if needed or 25 mg IV repeated every 4 to 6 hours for 24 hour

What is the BBW for Conjugated Estrogens?

- Increased risk of invasive breast cancer was observed in postmenopausal women using conjugated estrogens in combination with medroxyprogesterone acetate

- Estrogens with or without progestin should not be used to prevent dementia.

- The use of unopposed estrogen in women with a uterus is associated with an increased risk of endometrial cancer

- Estrogens with or without progestin should not be used to prevent cardiovascular disease DVT or PE (current or history); active or history of arterial thromboembolic disease (eg, stroke, MI); breast cancer (except in pts being treated for metastatic disease); estrogen-dependent tumor; hepatic impairment or disease; known protein C, protein S, antithrombin deficiency or other known thrombophilic disorders; pregnancy

What is the brand name of Cyclosporine, ophthalmic?

Restasis, Cequa

What is the drug class of Cyclosporine, ophthalmic?

Immunosuppressant Agent, Calcineurin Inhibitor

What is the normal adult dose of Cyclosporine, ophthalmic?

Ocular: 1 drop in both eyes every 12 hours

What is the BBW for Cyclosporine, ophthalmic?

None

What is the brand name of Dexamethasone?

Decadron

What is the drug class of Dexamethasone?

Corticosteroid

What is the normal adult dose of Dexamethasone?

PO, IM, IV: 0.5 to 9 mg/day in divided doses every 6 to 12 hours; dose depends upon condition being treated and response of patient

What is the BBW for Dexamethasone?

None

What is the brand name of Dutasteride?

Avodart

What is the drug class of Dutasteride?

5 Alpha Reductase Inhibitor

What is the normal adult of Dutasteride?

PO: 0.5 mg once daily

What is the BBW for Dutasteride?

None

What is the brand name of Etanercept?

Enbrel

What is the drug class of Etanercept?

Antirheumatic; Tumor Necrosis Factor (TNF) Blocking Agent

What is the normal adult dose of Etanercept?

SC: 50 mg once-twice weekly depending on disease state

What is the BBW for Etanercept?

- Patients receiving etanercept are at increased risk for serious infections which may result in hospitalization and/or fatality

- Lymphoma and other malignancies (some fatal) have been reported in children and adolescents receiving TNF-blocking agents, including etanercept.

- Active tuberculosis (disseminated or extrapulmonary), including reactivation of latent tuberculosis, has been reported in patients receiving etanercept

What is the brand name of Evolocumab?

Repatha

What is the drug class of Evolocumab?

Antilipemic agent, PCSK9 Inhibitor

What is the normal adult dose of Evolocumab?

SC: 140mg every 2 weeks OR 420 mg once monthly

What is the BBW for Evolocumab?

None

What is the brand name of Ibandronate?

Boniva

What is the drug class of Ibandronate?

Bisphosphonate

What is the normal adult dose of Ibandronate?

- PO: 150 mg once monthly

- IV: 3 mg every 3 months

What is the BBW for Ibandronate?

None

What is the brand name of Levonorgestrel?

Plan B

What is the drug class of Levonorgestrel?

Contraceptive, Progestin

What is the normal adult dose of Levonorgestrel?

- PO: Two-dose regimen: One 0.75 mg tablet as soon as possible within 72 hours of unprotected sexual intercourse; a second 0.75 mg tablet should be taken 12 hours after the first dose

- PO: Single-dose regimen: One 1.5 mg tablet as soon as possible within 72 hours of unprotected sexual intercourse

What is the BBW for Levonorgestrel?

None

What is the brand name of Medroxyprogesterone?

Depo-Provera. Depo-SubQ. Provera 104. Provera (tablets)

What is the drug class of Medroxyprogesterone?

Contraceptive, progestin

What is the normal adult dose of Medroxyprogesterone?

Contraception

- IM: 150 mg every 3 months

Endometriosis

- SC: 104 mg every 3 months

- PO: 5 or 10 mg daily for 5 to 10 days starting on day 16 or 21 of menstrual cycle

What is the BBW for Medroxyprogesterone?

- Long term use, loss of bone mineral density

- May cause suppression of hypothalamic-pituitary adrenal (HPA) axis

What is the brand name of Mometasone?

Nasonex. Sinuva Nasal (Implant)

What is the drug class of Mometasone?

Corticosteroid, Nasal

What is the normal adult dose of Mometasone?

- Nasal: 2 Sprays in each nostril daily

- Sinus Implant: 1 implant placed in sinuses every 90 days

What is the BBW for Mometasone?

None

What is the brand name of Raloxifene?

Evista

What is the drug class of Raloxifene?

Selective Estrogen Receptor Modulator (SERM)

What is the normal adult dose of Raloxifene?

PO: 60 mg daily

Patients should receive supplemental calcium and vitamin D if dietary intake is inadequate

What is the BBW for Raloxifene?

- Increase the risk for DVT and PE; use is contraindicated in patients with history of or current venous thromboembolic disorders

- Risk of death due to stroke is increased in postmenopausal women with coronary heart disease or at increased risk for major coronary events Pregnancy/Breast-feeding

What is the brand name of Ranolazine?

Ranexa

What is the drug class of Ranolazine?

Antianginal Agent

What is the normal adult dose for Ranolazine?

PO: 500 mg twice daily initially up to 1,000 mg twice daily

What is the BBW for Ranolazine?

None

What is the brand name of Solifenacin?

Vesicare

What is the drug class of Solifenacin?

Anticholinergic agent

What is the normal adult dose of Solifenacin?

Oral: 5 mg/day up to 10 mg/day

What is the BBW for Solifenacin?

None

What is the brand name of Tacrolimus?

Prograf. Astagraf XL. Envarsus Xr

What is the drug class of Tacrolimus?

Immunosuppressant agent, Calcineurin Inhibitor

What is the normal adult dose of Tacrolimus?

- IR PO: 0.1 to 0.15 mg/kg/day in 2 divided doses

- ER PO: 0.1 to 0.2 mg/kg daily

What is the BBW for Tacrolimus?

- Malignancies and serious infection

- Immunosuppressant agents, including tacrolimus, increase the risk of infection that may lead to hospitalization or death Hypertension

What is the brand name of Tolterodine?

Detrol LA

What is the drug class of Tolterodine?

Anticholinergic, overactive bladder

What is the normal adult dose of Tolterodine?

- IR PO: 2 mg twice daily; dose may be lowered to 1 mg twice daily based on individual response

- ER capsule PO: 4 mg once daily; dose may be lowered to 2 mg once daily

What is the BBW for Tolterodine?

None