Baltimore Classification

Viruses: Group I

dsDNA > mRNA

Viruses: Group 2

ssDNA > dsDNA > mRNA

Viruses: Group 3

dsRNA > mRNA
uses RNA-dependent RNA polymerase

Viruses: Group 4

ssRNA (+) > mRNA
uses RNA-dependent RNA polymerase

Viruses: Group 5

ssRNA (-) > mRNA > ssRNA (-) for viral genome
uses RNA-dependent RNA polymerase

Viruses: Group 6

ssRNA (+) > dsDNA > mRNA
uses REVERSE TRANSCRIPTASE

Viruses: Group 7

dsDNA > mRNA > dsDNA for viral genome
uses REVERSE TRANSCRIPTASE

Viruses: Group I examples

poxvirus, hpv, herpesvirus

dsDNA

single stranded dna

mRNA

single stranded RNA

Group 4 starting mRNA

positive single stranded

Group 5 starting mRNA

negative single stranded

Group 6 starting mRNA

negative single stranded

Group 5 ending mRNA

negative single stranded

Why do most DNA enter host nucleus

enzymes needed are there

Group 1 starting

double stranded DNA

Group 2 starting mRNA

single stranded DNA

Group 3 starting mRNA

double stranded RNA

Group 7 starting mRNA

double stranded DNA

Group 7 ending product

double stranded DNA

Enveloped virus gets envelope from

host cell

-sense RNA contains correct message from translation

positive

HIV can’t be cured because

has integrase

L1 function in HPV

Capsid formation

HPV replication is in

nucleus

HPV virions assembled in

nucleus

Influenza replication is in

nucleus

Virus with 2 identical positive RNA strands in capsid

HIV

Poxvirus

group 1

Polio

group 4

Does not require entry into host cell nucleus for replication

Poxvirus

Not targeted by current antiretroviral therapy

release of virions

Viruses: Group 2 examples

parovirus

Viruses: Group 3 examples

rotavirus

Viruses: Group 4 examples

coronavirus, polio

Viruses: Group 5 example

infuenza

Viruses: Group 6 example

retrovirus, hiv

Viruses: Group 7 example

hepadnavirus, hbv