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What are the two major regions of the respiratory system?
Conducting region and respiratory region
What structures are included in the conducting region?
Nasal cavity through terminal bronchioles
What is the main function of the conducting region?
Condition and conduct inspired air
What structures are included in the respiratory region?
Respiratory bronchioles through alveoli
What is the primary function of the respiratory region?
Gas exchange
What is ventilation?
Movement of air between atmosphere and lungs
What structures form the ventilatory mechanism?
Diaphragm, thoracic cage muscles, accessory muscles, and lung elastic tissue
What creates pressure differences during breathing?
Changes in thoracic volume
What are the 6 major functions of the respiratory system?
Ventilation, external respiration, internal respiration, phonation, olfaction, immunologic defense
What is pulmonary ventilation?
Inhalation and exhalation
What is external respiration?
Gas exchange between lungs and bloodstream
What is internal respiration?
Gas exchange between bloodstream and tissues
What is phonation?
Sound production from vibration of vocal cords
What is olfaction?
Sense of smell beginning in nasal cavity
Name 3 respiratory immunologic defenses.
Hair, coughing, sneezing
Do pleural sacs communicate across the midline?
No
What occupies the pulmonary cavities?
Lungs and pleurae
What occupies the mediastinum?
Trachea and thoracic organs
What are the two layers of pleura?
Visceral pleura and parietal pleura
Which pleura adheres to the lung surface?
Visceral pleura
Which pleura lines the thoracic wall?
Parietal pleura
What structures does the parietal pleura line?
Thoracic wall, mediastinum, diaphragm
What is the endothoracic fascia?
Loose connective tissue between thoracic wall and parietal pleura
What is the pleural cavity?
Potential space between pleural layers
What is found in the pleural cavity?
Thin layer of serous pleural fluid
What is the function of pleural fluid?
Lubrication and surface tension
How does pleural fluid help keep lungs expanded?
Surface tension couples lungs to thoracic wall
At what location are visceral and parietal pleura continuous?
Root/hilum of lung
What is the cupula?
Cervical pleura extending above first rib
What causes lung collapse if pleural pressure is lost?
Elastic recoil of lungs
Name the four parts of the parietal pleura.
Cervical, costal, diaphragmatic, mediastinal
What are pleural reflections?
Areas where parietal pleura changes direction
What is the bare area of the pericardium?
Area where pericardium contacts thoracic wall
At what ICS is the bare area located?
5th-6th intercostal space
What procedure accesses the pericardium through the bare area?
Pericardiocentesis
What are pleural recesses?
Areas where parietal pleura oppose each other
What is the largest pleural recess?
Costodiaphragmatic recess
Where does fluid commonly collect in the pleural cavity?
Costodiaphragmatic recess
At the midclavicular line, the pleural recess spans which ICS?
ICS 6-8
At the midaxillary line, the pleural recess spans which ICS?
ICS 8-10
At the paravertebral line, the pleural recess spans which ICS?
ICS 10-12
What can accumulate in pleural recesses?
Air, fluid, blood, pus
What is pleural effusion?
Accumulation of fluid in pleural cavity
What is another term for pleural effusion?
Hydrothorax
What symptoms are associated with pleural effusion?
Dyspnea, chest pain, dry cough
Name causes of pleural effusion.
CHF, pneumonia, TB, cancer, liver or kidney disease, mesothelioma, pulmonary embolism
What is empyema?
Pus in pleural cavity
What is another term for empyema?
Pyothorax
What commonly causes empyema?
Bacterial pneumonia
What is hemothorax?
Blood in pleural cavity
Common causes of hemothorax?
Trauma or pneumonia complications
What is pneumothorax?
Air in pleural cavity
How does pneumothorax affect intrapleural pressure?
Increases pressure and removes negative pressure
What symptoms occur in pneumothorax?
Chest pain and dyspnea
What is atelectasis?
Collapse of lung tissue
Where is chest tube insertion commonly performed?
Midaxillary line at 5th-6th ICS
What is thoracocentesis?
Needle aspiration of pleural fluid/air
Where is thoracocentesis commonly performed?
8th-9th ICS near/posterior to midaxillary line
Why must thoracocentesis avoid abdominal organs?
Prevent injury to liver or spleen
What surrounds the lungs?
Pleural cavity formed by pleurae
What suspends the lungs from mediastinum?
Root of lung
Where is the apex of the lung located?
Above first rib into root of neck
What is the base of the lung?
Concave inferior surface on diaphragm
How many lobes does the right lung have?
Three
How many lobes does the left lung have?
Two
What fissures are in the right lung?
Horizontal and oblique fissures
What fissure is in the left lung?
Oblique fissure
What is the lingula?
Left lung projection analogous to right middle lobe
What is the hilum?
Doorway for bronchi, vessels, nerves entering lung
What structure is usually superior in the hilum?
Pulmonary artery
What structure is posterior in the hilum?
Main bronchus
What carries deoxygenated blood to lungs?
Pulmonary arteries
What carries oxygenated blood from lungs?
Pulmonary veins
What is the pulmonary ligament?
Pleural fold inferior to lung root
What structures pass posterior to root of lung?
Vagus nerve and posterior pulmonary plexus
What structures pass anterior to root of lung?
Phrenic nerve and anterior pulmonary plexus
Why is the right lung shorter?
Right dome of diaphragm is higher
Why is the left lung narrower?
Heart occupies left thoracic space
At what vertebral level does the trachea bifurcate?
Sternal angle/T4-T5
What is the carina?
Ridge separating main bronchi
What type of cartilage supports trachea?
C-shaped hyaline cartilage
What epithelium lines the bronchi?
Pseudostratified ciliated columnar epithelium
How many lobar bronchi are in the right lung?
Three
How many lobar bronchi are in the left lung?
Two
What do segmental bronchi supply?
Bronchopulmonary segments
How many bronchopulmonary segments are in the right lung?
10
How many bronchopulmonary segments are in the left lung?
8-10
What structures follow terminal bronchioles?
Respiratory bronchioles
What structures follow respiratory bronchioles?
Alveolar sacs
What is a bronchopulmonary segment?
Functional surgical unit of lung
What structures define a bronchopulmonary segment?
Segmental bronchus and pulmonary artery branch
What separates bronchopulmonary segments?
Connective tissue septa
Why are bronchopulmonary segments clinically important?
Disease can remain localized
Can bronchopulmonary segments be surgically removed?
Yes
What is segmentectomy?
Removal of one or more bronchopulmonary segments
What is lobectomy?
Removal of a lung lobe
What is pneumonectomy?
Removal of entire lung
What is the primary site of gas exchange?
Alveoli
Which pneumocyte produces surfactant?
Type II pneumocyte
What is the function of surfactant?
Reduce alveolar surface tension