Chapter 9 Pathology Hematopoietic System

Hematopoietic System Consists of

blood, lymphatic tissue, bone marrow, and the spleen.

Albumins

regulate passage of water and solutes through the capillaries.

Basic Types of Blood Cells

Erythrocytes, leukocytes, and thrombocytes. Make up the remaining 45% of total blood volume.

Erythrocytes

Red blood cells. They do not possess a nucleus and are shaped like biconcave disks. Transport oxygen and Carbon dioxide to and from various organs of the body.

Universal Donor

type O blood, does not contain any antigens and can be given to anyone regardless of the recipient’s blood type.

Universal Recipient

The person with AB blood is considered this because it has both antigens.

Granular Leukocytes

Phagocytes containing cytoplasmic granules and irregular nuclei. They are formed within red bone marrow include neutrophils, eosinophils, basophils, and mast cells.

Lymphocytes

White blood cells important in building immunity.

Spleen

Largest lymphoid organ and is located in the upper left quadrant of the abdomen. Its chief function is to produce lymphocytes and plasma cells. It serves as a reservoir for blood and contains mononuclear phagocytes to cleanse blood.

Multiple Myeloma

A malignant neoplasm of plasma cells characterized by skeletal destruction, pathological fractures, and bone pain.

Myelocytic Leukemia

Acute- A cancer of the myeloid line of blood cells, characterized by the rapid growth of abnormal white blood cells that accumulate in the bone marrow and interfere with the production of normal blood cells.

Chronic- A form of leukemia characterized by the increased and unregulated growth of predominantly myeloid cells in the bone marrow and the accumulation of these cells in the blood.

Kaposi Sarcoma

present in the connective tissue of about one fourth of all patients with AIDS.

Bilirubin

bile pigment produced when hemoglobin breaks down. normal serum levels are equal or less than 1 mg per 100 mL but must exceed 3 mg per 100 mL to be visible of the absorber.

Acute Lymphocytic Leukemia

a rapidly progressing form of leukemia in which there are too many very young (immature) white blood cells called lymphoblasts, in the bloodstream and bone marrow.

Epstein-Barr Virus

has been linked to greater than 90% of the cases of Burkitt lymphoma.

plasma

The majority of blood volume is composed of

Erythrocytes

Bilirubin is formed during the destruction of

O

Which of the following is considered the universal donor type of blood

Neutrophils

Which type of leukocytes are the primary phagocytes responsible for responding to inflammation?

Lung

Which organs are a common site for opportunistic infections associated with HIV and AIDS?

The GI system, Lymph nodes, and skin

Kaposi Sarcoma is frequently associated with AIDS may affect

Multiple Myeloma

A neoplastic disease of plasma is called:

Acute Lymphocytic

Which type of leukemia predominantly affects children?

Hodgkin Lymphoma

With what type of neoplastic disease are Reed-Sternberg Cells associated?

Hodgkin Lymphoma

The Epstein-Barr Virus is associated with 90% of individuals diagnosed with which of the following disease?