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retroperitoneal
The paired kidneys are _____ in the superior lumbar region.
kidney , perirenal fat capsule
A fibrous capsule, a perirenal fat capsule, and renal fascia surround each ____. The ______ helps hold the kidneys in position.
superficial cortex , deeper medulla , medial pelvis.
A kidney has a _____, a ______ consisting mainly of medullary pyramids, and a _____.
apices
Extensions of the pelvis surround and collect urine draining from the ____ of the medullary pyramids.
25%
The kidneys receive ___% of the total cardiac output per minute at rest.
vascular pathway
The _____ through a kidney is as follows: renal artery → segmental arteries → interlobar arteries → arcuate arteries → cortical radiate arteries → afferent arterioles→ glomeruli → efferent arterioles →peritubular capillary beds → cortical radiate veins → arcuate veins → interlobar veins → renal vein.
renal plexus
The nerve supply of the kidneys is derived from the _____.
Nephrons
______ are the structural and functional units of the kidneys.
glomerulus , glomerular capsule , renal tubule
Each nephron consists of a ______ , a ________, and a ______ that is continuous with the capsule.
proximal convoluted tubule , nephron loop , distal convoluted tubule
Subdivisions of the renal tubule are the _______, ______, and ________.
renal tubule
A second capillary bed, the low-pressure peritubular capillary bed, is closely associated with the ____ of each nephron.
numerous cortical
The more ______ nephrons are located almost entirely in the cortex.
medulla
only a small part of their nephron loop penetrates into the _____.
cortex-medulla junction
Glomeruli of juxtamedullary nephrons are located near the ______, and their nephron loops dip deeply into the medulla.
straight vessels , vasa recta
Instead of directly forming peritubular capillaries, the efferent arterioles of many juxtamedullary nephrons form unique bundles of _____, called _____, that serve tubule segments in the medulla.
medullary osmotic gradient.
Juxtamedullary nephrons and the vasa recta play an important role in establishing the _______.
concentrate urine , medullary pyramids.
Collecting ducts receive urine from many nephrons and help ______. They form the ______.
afferent arteriole , distal part , ascending limb of the nephron loop.
The juxtaglomerular complex is at the point of contact between the ______ and the most _____ of the _______.
granular cells , macula densa , extraglomerular mesangial cells
The juxtaglomerular complex consists of the _____, the _____, and _________.
Filtration , absorption , secretion
______, ______, and ______ are the key processes of urine formation
glomerular filtration , tubular reabsorption , tubular secretion
Functions of the nephrons include _____, ______, and _____.
Kidneys
_____ regulate the volume, composition, and pH of the blood, and eliminate nitrogenous metabolic wastes.