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the main force that causes filtration in the nephron is
glomerular hydrostatic pressure
blood colloid osmotic pressure is generated by
presence of plasma proteins in the blood plasma
Lymphatic fluid is full of
Na, sodium
Bicarbonate ions bind to _____ creating carbonic acid. This is carried to the lungs and splits again into water and ______ which we exhale
H+, CO2
what does not increase the release of renin
increased blood volume
tubular reabsorption involves all the following
-cotransport
-active transport
-facilitated diffusion
-counter transport
The majority of water is reabsorbed by osmosis in the
proximal convoluted tubule
the majority of cotransporters and counter transporters are linked to the reabsorption of what ion
sodium
ICF is only found within
cells of the body
what hormone plays a central role in determine the rate of sodium reabsorption and potassium secretion
aldosterone
the primary role of the carbonic acid bicarbonate buffer system is to
buffer carbonic acid formed by carbon dioxide
Hypoventilation leads to
respiratory acidosis
Fluid balance involves the relationship between _____ and _____
Sodium, water
How does electrolyte balance keep osmolarity stable
By adjusting the fluid in the extracellular compartment
What are the two compartments of body fluids
intracellular fluid and extracellular fluid
what is a buffer
a substance that opposes a change in pH in a solution and can either remove or replace hydrogen ions
a volatile acid and produced from the combination of carbon dioxide and water
carbonic acid
Most of the total fluid in the body is
Intracellular fluid (approx. 63%)
ECF has HIGH concentrations of
sodium, chloride, and bicarbonate ions
ECF has LOW concentrations of
Potassium, magnesium,and phosphate ions
ICF has LOW concentrations of
sodium, chloride, and bicarbonate ions
ICF has HIGH concentrations of
Potassium, magnesium,and phosphate ions
Hydrostatic pressure drivers fluid out of the ______and into the ______
ECF, ICF
osmotic pressure drivers fluid out of the ______and into the ______
ICF, ECF
Dehydration is when
Water loss is greater than water gain... hypertonic
overhydration is when
The fluid flows into the ICF and the cell fills with fluid.... Hypotonic
What is the most abundant cation in the ECF
Na+ (sodium)
What is the most abundant cation in the ICF
K+ (potassium)
if Na+ in ECF increases, what happens to blood osmolarity
It increases
if Na+ in ECF decreases, what happens to blood osmolarity
It decreases
High potassium concentration is called
Hyperkalemia
What factors affect the rate of K+ secretion into urine
Changes in K+ concentration of ECF, aldosterone levels, and pH changes
A low blood pH is
Acidic
What happens when H+ ions are exchanged for Na+ in the DCT instead of K+ ?
It makes us acidic
What factors affect our acidity
H+ and CO2
When plasma pH is <7.3, it is called
Acidosis
When plasma pH is >7.4, it is called
Alkalosis
What systems are important in pH control
Buffer systems, respiratory system, and the urinary system
types of buffering systems
1. Phosphate buffer system
2. Protein buffer system
3. Carbonic acid-bicarbonate bugger system
What is the most important buffer system in the ECF
carbonic acid-bicarbonate buffer system
What is hypercapnia?
elevated carbon dioxide levels
What is metabolic acidosis?
When cells are producing large numbers of metabolic acids... involving H+ ions
Hypercapnia is primarily caused by
Hypoventilation
What is respiratory acidosis?
When the respiratory system cannot correctly eliminate the CO2 generated by tissues... involving PCO2