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what does the lymphatic system do?
transports, filters and cleans body fluids of pathogens, toxins and other unwanted substances
what does the extracellular body fluids include?
plasma in the bloodstream, interstitial fluid in tissues, lymph in lymphatic vessels and nodes
microscopic _________ _________ are very permeable
lymphatic capillaries
what does microscopic lymphatic capillaries feed into?
larger and larger lymphatic vessels and ducts
what are 3 functions of the microscopic lymphatic capillaries?
pick up excess interstitial fluid, route it through lymph nodes for filtering, and return it to the blood stream
what is the pathway of the lymph?
lymph always moves toward the heart and is eventually returned to the venous system through ducts
what does the right lymphatic duct do?
drains lymph from the upper, right side of the body
_________ ____ receives lymph from the rest of the body
thoracic duct
how does lymph move through the body?
contraction of skeletal muscles, pressure changes in the thoracic cavity, smooth muscle contractions in vessel walls
what is the function of the lymph nodes?
filter unwanted substances such as pathogens and cancer cells from the lymph
where is the primary site of lymphocyte production during an immune response
lymph nodes
what type of fiber acts as a net to catch debris?
reticular fibers
_________ live on the fibers
macrophages
_________ live within the spaces of reticular fibers
lymphocytes
what are the two types of white blood cells in lymph nodes
macrophages and lymphocytes
where do macrophages develop?
monocytes
what do macrophages do?
engulf and destroy bacteria and other foreign substances
what are two functions of lymphocytes?
monitor fluid for presence of antigens and can trigger an immune response
how do you know when an infection is present?
lymph nodes may swell and become tender
how are swollen lymph nodes caused?
by large numbers of trapped bacteria or viruses
how does metastasis occur?
cancer spreads to a new location in the body away from its original site
why does metastasis often happen through the lymphatic system?
the extreme permeability of lymphatic vessels
what is the function of the tonsils?
trap pathogens entering the throat
what is the function of the thymus?
involved in producing lymphocytes in children
what is the function of Peyer’s Patches?
capture and destroy bacteria in the small intestine
what is the function of the spleen?
filters pathogens and debris from blood
(1)
right lymphatic duct
(2)
thymus gland
(3)
axillary lymph node
(4)
peyer’s patches
(5)
appendix
(6)
red bone marrow
(7)
tonsils
(8)
cervical lymph node
(9)
entrance of thoracic duct subclavian vein
(10)
spleen
(11)
thoracic duct
(12)
cisterna chyli
(13)
lumbar lymph node
(14)
inguinal lymph node
(15)
pelvic lymph node
(1)
arteriole
(2)
endothelial cells
(3)
blood vessel capillaries
(4)
closed valves prevent backflow
(5)
venule
(6)
lymph flows through open valves
(7)
interstitial fluid
(8)
tissue cells
(9)
lymphatic capillaries