cAMP Signaling Pathway (Topic 6)

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Goal: glycogen breakdown in response to epinephrine or glucagon binding

Last updated 5:02 PM on 4/11/26
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5 Terms

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1.

Epinephrine binds to its GPCR

<p>Epinephrine binds to its GPCR</p>
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2.

G protein (Gs) is stimulated

<p>G protein (Gs) is stimulated</p>
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3.

Adenylyl cyclase enzyme is activated by the binding of Gsa-GTP

  • ATP is converted to cAMP

<p>Adenylyl cyclase enzyme is activated by the binding of Gsa-GTP</p><ul><li><p>ATP is converted to cAMP</p></li></ul><p></p>
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4.

cAMP binds to and activates Protein Kinase A (PKA)

<p>cAMP binds to and activates Protein Kinase A (PKA)</p>
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5.

PKA phosphorylates downstream targets related to the specific cellular event

<p>PKA phosphorylates downstream targets related to the specific cellular event</p>