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Validity
The instrument/method that accurately measures what the researcher intends to measure
Reliability
Instrument/method used to measure that produces consistent data
YPPL
Means years per life lost (if someone dies at 50 and the life expectancy is 75 years lost is 25)
DALY
Disability adjusted life year (add years of life lost and years with disability)
Communicable disease
Illnesses that spread through germs and bacteria (flu)
Non-communicable diseases
health conditions (cancer or heart disease)
Determinant vs Cause
Determinant is something that influences your health (where you live) and a cause is something that directly causes a health issue (smoking)
Factor
Anything that influences peoples health
Confounding Factor
Another factor that makes it harder to find out what is causing an issue within a population
Dose-Response
āmore is moreā āless is lessā refers to the relationship between the amount of exposure to a substance or intervention and the resulting effect on an organism.
Cost-benefit
deciding if something is worth it by comparing the benefits with the costs
Significance Test
If the difference between two groups or a result is due to chance or not
Normal Distribution
A bell shaped curve, average is in the middle. Extremes have lowest values in distribution
Nosology
classification of disease, helps group diseases based on symptoms and causes
Disease
We know the cause and how to treat it
Syndrome
The cause is unknown, a cluster of symptoms that people deal with (SIDS)
Cost-effectiveness
Getting the most bang for your buck- comparing costs of different programs to see which one gives the most health benefits with least amount spent
Opportunity Cost
The value that you could have done with those resources if you have chosen a different option/opportunity
Age pyramid
a picture that shows you how many people there are in different age groups
Ecological Fallacy
Assuming something is true for every person just because it is true for the group. (not everyone is poor in a pr neighborhood necessarily)
Epidemiological Shift
Perri Class- changes in the patterns of diseases and health conditions within a population over time
Phase 1 of drug testing
Evaluate safety of drug on small group of people
Phase 2 of drug testing
Test the efficacy and test the safety in a larger group
Phase 3 of drug testing
Monitor side effects, confirm efficacy
Reportable disease
illnesses that healthcare providers and labs must report them by law to public health authorities
Descriptive
Summarizing/describing data to understand whats happening in a population
Analyzing
using data to test hypothesis find out causes or risks
Prospective Study
Participants do not have the outcome (diseases) and are followed to see if they develop it in order to view the causes
Advantages- clear time sequence, better data quality, good for studying new cases
Disadvantages- Takes a long time, expensive, people may drop out, wait for results
Retrospective study
Participants already have the health issue and researchers look back in time to see what may have caused it
Advantages: Quick and cheap, good for rare conditions, gives an idea about causes
Disadvantages: People may not remember, limited info, no cause and effect
Garbage Code
Nonspecific code for cause of death. Can distort statistics by not saying direct cause of death (someone may smoke and actually die in a car accident)
Crude rate
Measures an occurrence overtime for the entire population
Specific rate
Measures an occurrence overtime for the subgroup of the population (ex: children)
Meta-Analysis
Take a whole bunch of different studies and data about one subject to compare to one another (forest graphs)
How are causes of non-communicable diseases established?
Cohort studies, case-control studies, studying cellular processes, physiological responses, population-level trends
Koch established an association between a potential cause and a disease outcome
Saracciās criteria for evaluating health claims
Trust new findings only if replicated
It isnāt always black and white
Trust findings only if placed in context
Donāt trust findings based on advertisements (only used to make money)
Take time to cross-check info
Three frameworks for measuring health
Social determinants of health, County health rankings, Social Ecological Model
Social determinants of health
Food, education, economy, healthcare, housing, and employment
Bradford Hills Criteria for causation
Strength of association
consistency
specificity
Temporality
Biological Gradient (dose response)
Plausibility
Coherence
Experimental Evidence
Analogy
Kochās Postulates
Microorganism must be found in abundance- not in healthy organisms
Must be isolated from a diseased organism and grown in a pure culture
Microorganism should cause a disease in a healthy individual
Microorganism should be reisolated and identified as identical to the original causing agent
Impact of epidemiology
Clinical medicine
Public health policy
Individual behavior
Aetiological Epidemiology
Looking for links between health and disease
descriptive epidemiology
The prevalence of the disease and details
Evaluative epidemiology
Estimates risks and evaluates interventions of health issues
Health Services Epidemiology
Studies health systems and their impacts on health in populations
Clinical Epidemiology
Studies the course of a disease in a population overtime
Randomized Control Trials
The test of the effectiveness of a drug on someone in an experiment (control and testing groups)
Cohort study
An observational study that measures the correlation between exposure and outcome of a disease
Case Control Study
An observational study that tracks characteristics and events over time
Confidence interval
A way to show how sure we our about out estimate by providing a range of values (forest plot)
Significance test
Check to be sure how likely a result is due to chance
Selection bias
When a population is not representative of the poopulation
Summary of GBD (Global Burden of Disease)
450 full time professionals in seattle
30+ full time faculty
scientific council
statisticians, data, and modeling professionals
outreach and training professionals
3,700 international collaborators
What does the GBD do?
Quantifies health loss from disease, injury, and risk factors and covers 195 countries
EPIC
European Prospective Investigation
cancer studies on how diet and nutrition effecting cancer
ICD
International Classification of Diseases
SIDS
Sudden Infant Death Syndrome
Health USA
National Health Database in the US talking about disease prevalence and mortality
Advantages- access to a wealth of data, monitor population health
Disadvantages- data might not be perfect or cover every health issue