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Opinion on Prolonging Human Life
Overall Controversy, Arguments in Favour, Arguments Against (Brenner's Critique), Artifactual Data, Human Data Limitations
What is the Overall Controversy
Whether this combination is likely to prolong human life remains highly controversial and lacks definitive clinical proof.
Arguments in Favour
the fundamental biology of aging is highly conserved from yeast to humans, and because these compounds improve healthspan and metabolic markers in mammals, they likely provide a similar "defense" mechanism in humans.
what does Professor Charles Brenner argue
that the sirtuin longevity hypothesis is a "mixture of framing bias, confirmation bias and hype."
what does Professor Charles Brenner argue point out about yeast
RLS is not a selected trait and that in chronological aging (CLS), which yeast actually faces in nature, deleting the SIR2 gene actually extends lifespa