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What is a key concept about neurons in synaptic transmission n
Neurons dont touch each other
Electrical message will not cross synapse as gap acts as a break in circuit
How is the message sent
Neurotransmitters released from vesicles and diffuses across synapse between 2 neurons
Presynaptic neuron release these
Once reach other side - bind to receptors on dendrite of postsynaptic neuron
If neuron gets enough excitation from n.t like dopamine attaching to its dendrites - action potential triggered - excitation passes a threshold and sends message of excitation along whole cell
What HAPPENS after message is sent on
The nt are released by receptor and re absorbed by presynpatic neuron
What is seretonin an example of
Inhibitory nt
Blocks negative impulses
What is an example of excitatory nt
Neroadrenaline
When neuron is not sending a signal what is it described as and why
Rest (inside s negatively charged relative to outside)
Higher conc of NA outside
What happens when neurons receive a go message from excitatory nt?
Gates in cell wall open and NA enters
Increases postoperative charge inside neuron
What happens when enough sodium has entered neuron
Threshold is passed and neuron fires
Action potential travels down axon - jumping from node ranvier to node ranvier
What does action potential trigger
Trigger vesicles in axon terminal to move to cell wall and rupture - release nt into next synapse
Nt bind to receptors on dendrites - cause excitatory effect or an inhibitory
If enough excitatory effect - new action potential
What is the term used to describe how action potentials cant be stopped
Ballisitic
What does excitation in a neuron mean
Increased in electrical activity
More likely to start action potential
Noradrenaline is e.g (cause next neuron to increase in excitation)
What does inhibition mean
Decreases in its electrical activity
Less likely to start action potential
Inhibitory nt - cause next neuron to become more inhibited
E.g seretonin
What is dopamine an example of
Both excitatory and inhibitory
What is summation
Process of adding things together
One neuron gets lots of presynaptic Nuerons firing at it (excitatory/inhibitory)
If excitatory input outweigh the inhibitory input - makes postysanptic neuron fire which triggers a new action potential
What are the 2 types of summation
Temporal - same presynaptic neuron fires at post until it becomes greater (fires repeatedly)
Spatial - multiple psn fir at same post s.n at moderate level but together they add up to enough excitation to trigger post s.n to fire