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Where is cerebral white matter located?
Internal to gray matter

What is the main function of cerebral white matter?
Communication within the CNS
“communication railway”
What is cerebral white matter composed of?
Myelinated axons organised into tracts
What do tracts in cerebral white matter do?
conduct information between the two cerebral hemispheres
conduct information between cortical areas in the same hemisphere
conduct information between the cerebral cortex and lower parts of the CNS (e.g., thalamus, spinal cord)
Where are the cerebral basal nuclei located?
Embedded deep within the white matter
Islands of gray matter deep within the white matter

What is the main function of the basal nuclei?
Facilitate smooth skeletal muscle movements
Communicate with the motor areas of the cerebral cortex to facilitate smooth skeletal muscle movements
What regulates the activity of the basal nuclei?
Dopamine
What happens when dopamine is lost?
Basal nuclei become overactive, leading to Parkinson’s disease