17: Pharynx: Nasopharynx cancer

0.0(0)
Studied by 0 people
call kaiCall Kai
learnLearn
examPractice Test
spaced repetitionSpaced Repetition
heart puzzleMatch
flashcardsFlashcards
GameKnowt Play
Card Sorting

1/16

encourage image

There's no tags or description

Looks like no tags are added yet.

Last updated 9:25 PM on 11/9/25
Name
Mastery
Learn
Test
Matching
Spaced
Call with Kai

No analytics yet

Send a link to your students to track their progress

17 Terms

1
New cards

the area below the base of brain, posterior to the nasal cavity and above the soft palate

nasopharynx

<p>nasopharynx </p>
2
New cards

The nasopharynx includes the following structure

adenoids

<p>adenoids </p>
3
New cards

the nasopharynx extends on a line from the ___ to the ___

zygomatic arch to EAM

<p>zygomatic arch to EAM</p>
4
New cards

The ___ drains into the nasopharynx

nasal cavity

<p>nasal cavity</p>
5
New cards

Nasopharynx epidemiology

highest incidence in China + Middle Eastern Countries

<p>highest incidence in China + Middle Eastern Countries </p>
6
New cards

Nasopharynx cancer etiology 

  1. one of the few H&N cancers NOT associated with tobacco use

  2. EBV

7
New cards

Nasopharynx cancer pathology

squamous cell carcinoma (most)

8
New cards

Nasopharynx presentation (symptoms) , bold the most common one

  1. painless neck mass

  2. nasal obstruction & bleeding

  3. Ear pain and hearing loss (fyi: cuz Eustachian tube gets blocked)

  4. Sore throat

  5. headache

  6. facial pain

  7. cranial nerve abnormalities (in advanced disease)

PENS CFhey

9
New cards

Nasopharynx patterns of spread

  1. aggressive local invasion: along lateral pharyngeal walls into oropharynx and/or into base of skull and sphenoid sinus

  2. blood borne mets  

  3. lymphatics: most patients have it at the time of diagnosis

10
New cards

The vast majority of nasopharynx patients have positive ___ nodes at diagnosis

cervical

11
New cards

What are the 1st station nodes for nasopharynx cancer?

  1. jugulodigastric

  2. posterior cervical

  3. lateral retropharyngeal aka Rouvier’s Node

<ol><li><p>jugulodigastric</p></li><li><p>posterior cervical</p></li><li><p>lateral retropharyngeal aka Rouvier’s Node</p></li></ol><p></p>
12
New cards

Treatment for Nasopharyngeal

Surgery: NPC not accessible to surgery

RTT: Most common modality

Chemo: concomitant with RTT for stages II & IV

 

<p>Surgery: NPC not accessible to surgery</p><p>RTT: Most common modality</p><p>Chemo: concomitant with RTT for stages II &amp; IV</p><p>&nbsp;</p>
13
New cards

NPC RTT fields

Large POP fields encompassing:

  1. nasopharynx

  2. all surrounding structures

Supraclavicular field:

  1. bilateral neck nodes to clavicles

Fields must include Rouvier’s node

14
New cards

NPC doses

+65 Gy (high dose)

70 Gy- if there are + nodes OR bulky disease

15
New cards

NPC RTT borders

Superior

Inferior

Anterior

Posterior

Superior: 2 cm beyond tumor- to include Base of Skull + Sphenoid sinuses

Inferior: thyroid notch- to spare larynx

Anterior: include posterior 1/3 of maxillary sinus + nasal cavity. More anterior tumors need 2cm margin.

Posterior: 2 cm margin beyond mastoid process OR posterior margin may extend further 1.5 cm margin on enlarged nodes

<p>Superior: 2 cm beyond tumor- to include Base of Skull + Sphenoid sinuses</p><p>Inferior: thyroid notch- to spare larynx</p><p>Anterior: include posterior 1/3 of maxillary sinus + nasal cavity. More anterior tumors need 2cm margin.</p><p>Posterior: 2 cm margin beyond mastoid process OR posterior margin may extend further 1.5 cm margin on enlarged nodes </p><p></p>
16
New cards

How should local failures of NPC be treated?

external beam followed by brachy

17
New cards

NPC 5 year

45%

(N45al)