Quality Control Lecture Notes

Vocabulary flashcards covering the introductory concepts of Quality Control, types of errors, accuracy/precision, and pharmaceutical analysis methods based on the lecture notes.

Quality Control

A part of Good Manufacturing Practice concerned with sampling, specifications, and testing, and with the organization, documentation, and release procedures which ensure that necessary tests are carried out and materials are not released until their quality has been judged satisfactory.

Determinate Errors

Also known as constant errors; these recur in a constant manner in a series of determinations, are usually detectable, and may be eliminated to a large extent.

Indeterminate Errors

Also known as accidental errors; these are slight variations in a series of observations made by the same observer under identical conditions due to unknown and intangible causes.

Accuracy

The closeness of a result to the true value.

Precision

The closeness of results with one another.

Absolute error

The difference between the mean and the true value.

Relative error

The value found by dividing the absolute error by the true value.

Gravimetric Analysis

The measurement of the weight of a substance in a sample or the calculation of the weight of a substance from the weight of a chemically equivalent amount of another substance.

Dried to constant weight

A state where two consecutive weighings do not differ by more than $0.5\,mg/g$ of the substance when the second weighing is made after an additional hour of drying.

Volumetric Analysis

One of the three general methods used in official pharmaceutical analyses alongside Gravimetric and Gasometric analysis.

Gasometric Analysis

One of the quantitative pharmaceutical analysis methods used in official pharmaceutical analyses.