Antibody-Drug Conjugates 2

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Last updated 2:31 PM on 5/6/26
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9 Terms

1
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Overview of ADCs for cancer treatment

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2
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Conjugation (addition of payload) strategies: Lys coupling

Ideally the conjugation stie will not be in the variable region as it can and probably will affect binding

<p>Ideally the conjugation stie will not be in the variable region as it can and probably will affect binding</p>
3
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Lys coupling methods

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Conjugation strategies: Cys coupling

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Cys coupling methods

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Conjugation Strategies: Unnatural Amino Acid Incorporation

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Cleavable vs non-cleavable linkers

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Payload release graph and linker stability

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Drug delivery to the brain: methods

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