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The intake of food into the mouth.
ingestion
What is the function of saliva?
Lubricates food and begins chemical digestion.
What enzyme is found in saliva?
salivary amylase
What does salivary amylase digest?
Starch into smaller carbohydrates
What is the function of the esophagus?
Transport food from the mouth to the stomach.
How does food move through the esophagus?
by peristalsis
Does digestion occur in the esophagus?
no
What are the main functions of the stomach?
Storage, churning of food, and chemical digestion.
What is the pH of the stomach?
Very low (highly acidic)
What is gastric juice?
A mixture of HCl, pepsinogen, and mucus.
What is the function of hydrochloric acid (HCl)?
Denatures proteins and activates pepsin.
A protease that digests proteins.
pepsin
How does the stomach protect itself from digestion?
A thick mucus layer protects the stomach wall.
What is the basic gross structure of the stomach?
Muscular sac with folds called rugae.
Where is the liver located?
upper right abdomen
How is the liver structurally related to the GI system?
Connected via bile ducts to the small intestine.
What does the liver produce for digestion?
bile
What is the liver’s role in blood glucose regulation?
Stores glucose as glycogen and releases glucose when needed.
What is the liver’s role in detoxification?
Metabolizes drugs, alcohol, and toxins.
A digestive fluid that emulsifies fats.
-Breaks large fat droplets into smaller droplets to increase surface area.
bile
Where is bile produced?
liver
Where is bile stored?
gallbladder
What digestive enzymes does the pancreas produce?
Amylase, lipase, proteases (trypsin, chymotrypsin).
How do pancreatic enzymes reach the small intestine?
through the pancreatic duct
does the pancreas have endocrine functions?
yes, insulin and glucagon secretion.
what is the main function of the small intestine?
Absorption of nutrients and water.
What are the three anatomic subdivisions of the small intestine?
Duodenum, jejunum, ileum.
Where does most chemical digestion occur?
duodenum
Increases surface area for absorption.
villi
What do lacteals inside villi absorb?
fats
Does the small intestine produce enzymes?
yes
How is stomach acid neutralized in the small intestine?
By bicarbonate from the pancreas.
What is the main function of the large intestine?
absorption of water and electrolytes.
What is the role of bacterial flora?
Produce vitamins (K, B) and ferment undigested material.
What is the gross structure of the large intestine?
Cecum, colon, rectum.
What is the function of the rectum?
storage and elimination of feces.
Rhythmic muscular contractions that move food through the GI tract.
peristalsis
Is peristalsis voluntary or involuntary?
involuntary
What hormones regulate digestion?
Gastrin, secretin, cholecystokinin (CCK).
What does gastrin stimulate?
HCl secretion in the stomach.
What does secretin stimulate?
Bicarbonate release from pancreas.
What does CCK stimulate?
Pancreatic enzyme release and gallbladder contraction.
A network of neurons that independently controls digestion; part of the autonomic system
enteric nervous system
What processes does the digestive system regulate?
Peristalsis, secretion, and blood flow.
Mouth =
ingestion + amylase
Esophagus =
transport
Stomach =
acid + protein digestion
liver =
bile + detox + glucose regulation
Gallbladder =
bile storage
Pancreas =
digestive enzymes + insulin/glucagon
Small intestine =
digestion + absorption
Villi =
surface area
Large intestine =
water absorption
Rectum =
waste storage
Peristalsis =
movement
Gastrin, secretin, CCK =
hormone control
Enteric nervous system =
automatic digestion control