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Ischemia
an interference with the blood supply to an organ or part of an organ, depriving the organ’s cells and tissues of oxygen and nutrients
Infarction
a localized area of ischemic necrosis within a tissue or organ produced by occlusion of either its arterial supply or its venous drainage
Hemorrhage
the rupture of a blood vessel
Malignant
neoplasms that invade and destroy adjacent structures and spread to distant sites
Hypertrophy
an increase in the size of the cells of a tissue or organ in response to a demand for increased function
Edema
the accumulation of abnormal amounts of fluid in the intercellular tissue spaces or body cavities
Hyperplasia
an increase in the number of cells in a tissue or organ
Atrophy
a reduction in the size or number of cells in an organ or tissue, with a corresponding decrease in function
Neoplasia
an abnormal proliferation of cells that are no longer controlled by the factors that govern the growth of normal cells.
Benign
tumors that closely resemble their cells of origin in structure and function and remain localized
Atelectasis
a condition in which there is diminished air within the lung associated with reduced lung volume
Pleural Effusion
the accumulation of fluid in the pleural space
Pneumothorax
the presence of air in the pleural cavity, results in a partial or complete collapse of the lung
Chronic Obstructive Pulmonary Disease (COPD)
includes several conditions in which chronic obstruction of the airways leads to an ineffective exchange of respiratory gases and makes breathing difficult
Pneumonia
an inflammation of the lung that can be caused by a variety of organisms, most commonly bacteria and viruses
Dissection of the Aorta
A potentially life-threatening condition in which disruption of the intima (the inner layer) permits blood to enter the wall of the aorta and separate its layers
Thrombus
an intravascular clot
Embolism
a thrombus that becomes detached from the vessel wall and enters the bloodstream
Aneurysm
a localized dilation of an artery that most commonly involves the aorta, especially its abdominal portion
Congestive Heart Failure
the inability of the heart to propel blood at a rate and volume sufficient to provide an adequate supply to the tissues
Hypertension
high blood pressure
Arteriosclerosis
occurs when arteries become marked by thickening, hardening, and loss of elasticity in the arterial wall
Pericardial Effusion
the accumulation of fluid within the pericardial space surrounding the heart
Deep Venous Thrombosis
primarily involves the lower extremities and is the major source of potentially fatal pulmonary embolism
Atherosclerosis
Plaque that develops in the intima of the artery
Osteoporosis
a generalized or localized deficiency of bone matrix in which the mass of bone per unit volume is decreased in amount but normal in composition
Spina bifida
a posterior defect of the spinal canal resulting from failure of the posterior elements to fuse properly
Bursitis
an inflammation of the bursae
Osteomalacia
too insufficient mineralization of the adult skeleton
Osteoarthritis
loss of joint cartilage and reactive new bone formation
Chondrosarcoma
a malignant tumor of cartilaginous origin
Enchondroma
a slow-growing, benign, cartilaginous tumor arising in the medullary canal
Gout
a disorder in the metabolism of purine in which an increase in the blood level of uric acid leads to the deposition of uric acid crystals in the joints, cartilage, and kidney
Paget disease
Destruction of bone, followed by a reparative process, results in weakened, deformed, and thickened bony structures that tend to fracture easily
Osteochondroma
a benign projection of bone with a cartilaginous cap that arises in childhood or the teen years