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5-HTT gene
important in production and use of seratonin
Aim of Caspi et al
to investigate why stressful life events seem to lead to depression in some people and not others
Amount of participants
847
Procedure
researchers measure stressful life events between the 21st birthday to the 26th birthday. Researcher counted the severity and number of stressful events. This was compared to depression outcomes
Conclusion
long alleles seem to protect against depression, a person need a specific gene and a stressful life events
Strengths of Caspi et al
generalisability due to large sample, standardized procedure
Weaknesses of Caspi et al
Genes are complex and actions of other genes cannot be controlled, symptoms of depression were self reported