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bipolar 1
dramatic mood fluctuations cycling from depression to mania
bipolar 2
mood fluctuations from depression to hypomania (less intense)
lithium mood stabilizer
narrow therapeutic index, and toxicity can be fatal, blood draws required
symptoms of lithium toxicity
gi distress, ataxia, sedation, seizures
Lithium considerations
teach client to maintain consistent sodium intake and drink 2-3L/day, starts to work in 1-3 weeks, will use benzos or atypical antipsychotics in meantime
what 3 anticonvulsants are used as mood stabilizers? and their effects?
valproate (hepatotoxicity and pancreatitis), carbamazepine and lamotrigine (monitor for rash stevens johnson syndrome)
Delirium causes THINK
toxins (drugs anticholinergics, sedatives), Hypoxemia, infection (uti, pneumonia), Nonpharm (missing hearing aids or glasses), K or (fluid and electrolyte imbalances)
The 3 S’s of serotonin syndrome
sweating (fever and increased HR), shaking (tremors muscle rigidity), strange behavior (mental status changes, confusion, agitation)
major depressive disorder
depression lasting more than 2 weeks
seasonal affective disorder
depression follows seasonal pattern
anorexia signs
low body weight, decreased HR and BP, dehydration, hypokalemia, decreased cognition and energy, amenorrhea
bulimia signs
normal body weight, dental erosion, scarring and calluses on hands, dehydration, hypokalemia
cluster a disorders
(odd and eccentric), paranoid, schizoid, schizotypal
cluster B personality disorders
(dramatic and erratic) antisocial, borderline, histrionic, narcissistic
cluster c personality disorders
(anxious and fearful) avoidant, dependant, obsessive compulsive
dialectical behavior therapy
teaches emotion regulation, distress tolerance, and interpersonal skills (borderline effective)
what is the primary treatment for personality disorders?
psychotherapy
paranoid personality disorder
suspicious of others, reads hidden meaning to remarks, easily offended, hypervigilant
antisocial personality disorder
disregards societal norms, lies, manipulates, disregards the rights of others, lacks guilt and remorse
borderline personality disorder
high risk for self-injury/suicide, unstable moods and relationships, fears abandonment, impulsive
narcissistic personality disorder
exaggerated self-importance, needs praise and admiration, lacks empathy
dependant personality disorders
struggles to function independently, fears abandonment, clings to others, lacks confidence, needs constant reassurance
positive schizophrenia symptoms
delusions, hallucinations, disorganized thinking
negative schizophrenia symptoms
anhedonia, avolition (lack of motivation), anhedonia, asocial behaviors, anergia, alogia, apathy
which first gen (typical) antipsychotics are used for schizophrenia?
haloperidol, fluphenazine, chlorpromazine
which second gen (atypical) antipsychotics are used for schizophrenia?
risperidone, ziprasidone, clozapine
EPS symptoms
akathisia, dystonia, pseudo parkinsonism, tardive dyskinesia (irreversible)
what two side effects do antipsychotics cause?
anticholinergic and orthostatic hypotension
first gen conventional antipsychotics names
chlorpromazine, fluphenazine, thioridazine, haloperidol
second gen antipsychotic names
aripiprazole, clozapine, olanzapine, quetiapine, risperidone, ziprasidone
cautions with 1st gen antipsychotics
NMS life threatening reaction characterized by fever, muscle rigidity, AMS
considerations with first gen antipsychotics
EPS akathisia, dystonia, pseudoparkinsonism
atypical antipsychotics cautions
agranulocytosis most likely to occur with CLOZAPINE, immediately report signs of infection (fever, sore throat, chills)
considerations atypical antipsychotics
metabolic syndrome teach healthy diet and exercise to manage weight
SSRI names
citalopram, fluoxetine, sertraline
SNRI names
duloxetine, venlafaxine
TCAS names
amitriptyline, imipramine, nortriptyline
MAOIs names
isocarboxazid, phenelzine, selegiline
bupropion antidepressant avoid administering to what clients?
clients with seizure disorder because of increased risk for seizures
mirtazapine antidepressant risk for?
sedation and weight gain
SSRIs considerations
sexual side effects common, take with food and drink to avoid GI effects, do not stop abruptly
SNRIs considerations
obtain baseline BP and monitor throughout treatment
TCA cautions
baseline ECG to assess for dysrhythmias, avoid alert activities, take at bedtime
TCA considerations
orthostatic hypotension, anticholinergic effects, and monitor for urinary retention
MAOI cautions
don’t combine with SSRIs or TCAs, washout period of more than 2 weeks is required to start or stop MAOI, risk for HTN crisis AVOID FOODS WITH TYRAMINE (cured meats, aged cheeses, beer, wine)