Top 25 drugs

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Atorvastatin

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1

Atorvastatin

Brand-Lipitor Class- HMG-CoA reductase inhibitor (Statin) Approved drug uses- Hypercholesterolemia Common adverse rxns-Diarrhea, arthalgia,nasopharyngitis,nausea, UTI, insomnia, limb pain, myalgia, pharyngolaryngeal pain Normal adult dose- 10-80mg po qd Crush- Yes Black Box warning- none

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2

Levothyroxine

Brand-Levoxyl, Levothroid, Synthroid Class- Hormone, thyroid Approved drug uses- hypothyroidism Common adverse rxns- palpitations, nervouseness, tremor,diarrhea, insomnia, fever, alopecia, heat intolerance, nausea, rash, disphoresis Normal adult dose- individualized po qd Crush- Yes Black box warning- not to be used for weight loss

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3

lisinopril

Brand- Prinivil, Zestril Class-Angiotensin converting enzyme inhibitor (ACE) Approved drug uses- Hypertension, heart failure Common adverse rxns- Dizziness, hypotension, hyperkalemia, cough, headache, fatigue, photosensitivity Normal adult dose- 5-40mg po qd Crush- yes Black box warning- Do not use during pregnancy

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4

metformin

Brand- glucophage, glucophage XR, glumetza, fortamet Class-biguanides Approved drug uses- Diabetes type 2 Common adverse rxns- diarrhea, nausea, vomiting, flatulence, abdominal discomfort, dyspepsia, headache, asthenia Normal adult dose- 500-1000mg po BID Crush- ER form- No Black box warning- none

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5

amlodipine

Brand-norvasc Class- Calcium Channel Blocker (CCB) Approved drug uses- Hypertension, heart failure Common adverse rxns- peripheral edema, fatigue,flushing, palpitations,dizziness, nausea, abdominal pain, pruritus Normal adult dose- 5-10mg po qd Crush- Yes Black box warning- none

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6

metoprolol

Brand- lopressor, toprol-XL Class- Selective beta- adrenergic blocker (B1) Approved drug uses- Hypertension, angina, cardiovascular event prevention, migrain Common adverse rxns- hypertension, bradycardia, pruritus, diarrhea, dizziness, depression, bronchospasm Normal adult dose- 50-100 mg po qd; 20-200 mg po qd Crush- ER form- no Black Box warning- Do not stop abruptly- taper dose

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7

albuterol inhaled

Brand- Proventil HFA, Ventolin HFA, ProAir HFA Class-Beta-2 agonists, inhaled short acting (SABAs) Approved drug uses- Bronchospasm Common adverse rxns- Nervousness, tremor, exacerbation of asthma, pharyngitis, tachycardia, dizziness, inc serum glucose, nausea, throat irritation, diarrhea Normal adult dose- 1-2 puffs q4-6hr prn Crush- DNA Black Box Warning- none

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8

Omeprazole

Brand- Prilosec Class-PPI Approved drug uses- GERD, gastric ulcer, H. pylori infection Common adverse rxns- Diarrhea, headache, abdominal pain, nausea, flatulence, dizziness, rash, upper resp infx Normal adult dose- 20mg po qd Crush- No

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9

Losartan

Brand-Cozzar Class-Angiotension receptor blockers (ARB) Approved drug uses- Hypertension, diabetic neurpathy, stroke prevention Common adverse rxns- upper respiratory infx, hypotension, dizziess, nephropathy, cough, headache, vertigo Normal adult dose- 50-100 mg po qd Crush- Yes Black Box Warning- Not to be used during pregnancy

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10

Simvasratin

Brand- Zocor Class-HMG- CoA reductase inhibitors (statins) Approved drug uses- hypercholesterolemia, hypertriglyceridema, Cv event prevent Common adverse rxns- Upper resp. infx, headache, abdominal pain, constipation, gastritis, atrial fibrillation, vertigo Normal adult dose- 5-40mg po qPM Crush- yes Black box warning- none

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11

gabapentin

Brand- neurontin, horizant Class- anticonvulsant Approved drug uses- partial seizures, neualgia Common adverse rxns- dizziness, ataxia, fatigue, nystagmus, tremor, diarrhea, headache, depression, amnesia, asthenia, hostility, amblyopia Normal adult dose- 300-1200 mg po tid Crush- Xr form- no black box warning-none

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12

hydrocodone and acetaminophen

Brand- lortab, norco Class-opiod combinations, narcotic + non-narcotic Approved drug uses- Pain,moderate to severe Common adverse rxns- consipation, nausea, headache, vomiting, anxiety, UTI, insomnia, dizziness, fatigue, diarrhea Normal adult dose- 2.5-10mg hydrocodone po qd q4-6hrs prn Crush- yes Black Box Warning- avoid doses of APAP that are higher than 4000mg per a day

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13

hydrochlorothiazide

Brand- Esidrix, Microzide Class-Thiazide diuretic Approved drug uses- hypertension, peripheral edema Common adverse rxns- hypokalemia, hypochloremia, hyponatremia, hypouricemia, hyperlipidemia, hyperglycemia, dizziness, headache, rash, photosensitivity Normal adult dose- 12.5-50 mg po qd Crush- yes Black box warning- none

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14

Sertraline

Brand-Zoloft Class- Selective serotonin reuptake inhibitor (SSRI) Approved drug uses- Major depressive disorders, obsessive-compulsive disorder, panic disorder Common adverse rxns- nausea, diarrhea, xerotomia, palpitations, fatigue, dizziness, tremor, agitation, constipaion, decreased libido, dec appetite Normal adult dose- 50-200 mg po qd Crush- yes black box warning- may cause suicidal thoughts in young adults and children

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15

montelukast

Brand- singulair Class-leukotriene inhibitor Approved drug uses- bronchospasm, allergic rhinitis Common adverse rxns- headhaches, abdominal pain, cought, diarrhea, dyspepsia, rash, anxiety, tremor Normal adult dose- 10mg po qd Crush- yes black box warning- serious neuropsych events. agitation, aggression, depression, hallucinations, suicidal thoughts

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16

fluticasone inhaled

Brand- flovent diskus, flovent HFA Class- corticosteroid inhaled Approved drug uses- asthma Common adverse rxns- headaches, throat irritation, candidiasis, cough, nausea, arthralgia Normal adult dose- disk- 1-2 puffs BID; HFA 2-4 puffs BID Crush- DNA Black box warning- none

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17

amoxicillin

Brand- Amoxil, Moxatag Class- Penicillin Antibiotic Approved drug uses- Bacterial infections Common adverse rxns- Nausea, vomiting, diarrhea, rash Normal adult dose- 250-500mg po q8h Crush- Er form- no Black box warning- none

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18

furosemide

Brand- Lasix Class- loop diuretics Approved drug uses- edema Common adverse rxns- dizziness, nausea, muscle cramps, hypokalemia, rash, hypomagnesemia Normal adult dose- 40-120 mg po divided qd-BID Crush- yes Black box warning- can cause proufound water and electrolyte depletion

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19

Pantoprazole

Brand- Protonix Class- PPI Approved drug uses- GERD, H. pylori infection Common adverse rxns- diarrhea,headache, abdominal pain, nausea, flatulence, dizziness, vertigo, myalgia Normal adult dose- 20mg po/iv qd Crush- no black box warning- none

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20

Prednisone

Brand-Sterapred, Sterapred DS Class- corticosteroid Approved drug uses- asthma, inflammation, adrenal insufficiency, gout, multiple-sclerosis Common adverse rxns- hirsutism, weight gain, erythema, abdominal discomfort,rash, nausea, vomiting, fluid retention, dizziness, anxiety, depression Normal adult dose- 5-60 mg po qid Crush- DR form- no

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21

escitslopram

Brand-lexapro Class--Selective serotonin reuptake inhibitor (SSRI) Approved drug uses- major depressive disorder, generalized anxiety disorder Common adverse rxns- nausea, headache, ejacuatory dysfxn, insomnia, diarrhea, fatigue, dizziness, constipation, anorexia, abnormal dreams, abdominal pain Normal adult dose- 10mp po qd Crush- yes Black Box warning- May cause suicidal thoughts in children and young adults

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22

fluoxetine

Brand- prozac, prozac weekly, sarafem Class-Selective serotonin reuptake inhibitor (SSRI) Approved drug uses- major depressive disorder, obessive compulsive disorder, panic disorder, premenstrual dysphoric disorder Common adverse rxns- nausea, headache, diarrhea, dizziness, constipation, anorexia, abnormal dreams, nervousness, tremor, anxiety, drowsiness Normal adult dose- 20-80mg po qAM Crush- DR form- No Black Box warning- May cause suicidal thoughts in children and young adults

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23

amphetamine + dextroamphetamine

Brand-Adderall, Adderall XR Class- Noewpinephrine- dopamine reuptake inhibitors (NDRIs), ADHD Approved drug uses- ADHD, narcolepsy Common adverse rxns- anorexia, insomnia, headache, emotional lability, anxiety, agitation, nervousness, diarrhea, tachycardia, visual disturbance, photosensitvity Normal adult dose- 5-40 mg po qd tidEr; 20mg po qAM Crush- ER form NO Black Box Warning- high abuse potential, monitor for signs of abuse or dependence

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24

Tramadol

Brand- ConZip, Qdolo Class-Opiod agonist Approved drug uses-Pain, moderate to moderate-severe Common adverse rxns- Somnolence, constipation, vomiting, dizziness, anxiety, dysphoria, confusion, headache, asthenia Normal adult dose- 50-100mg po q4-6hr Crush- ER form- No Black Box warning- high addiction/misuse risk opioid analgesic REMS Life threatening respiratory depression can occur Concomitant use with BZDP

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25

insulin glargine

Brand- Lantus, basaglar, toujeo Class- Insulin (long acting) Approved drug uses- Diabetes type 1 and 2 Common adverse rxns- Hypoglycemia, inj, site reaction, site lipodystrophy, myalgia, rash Normal adult dose- individualized given SC qd Crush- DNA Black Box warning- none

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