Sedation Meds

What are Benzodiazepines used for?

Anxiolysis, amnesia, anti-convulsive, skeletal muscle relaxation, sedative

What is the initial IV dose for Midazolam (Versed)?

1-2 mg

How long does it take for Midazolam (Versed) to start working in the body?

1-2 min

How long does it take for IV Midazolam (Versed) to reach peak effect?

3-5 min

How long do the effects of IV Midazolam (Versed) last?

10-30 min

What are the effects of Ketamine?

Dissociative anesthetic, analgesic, amnestic

What is ketamine used for?

short term procedures requiring intense analgesia

What are contraindications Ketamine?

increased ICP, corneal laceration (increases ICP)

What is the recommended dosage for Ketamine?

0.25-0.5 mg/kg IV or 1-2 mg/kg IM

How long does it take IV Ketamine to work in the body?

less than 60 sec

How long does it take for IV Ketamine to reach peak effect?

5-10 min

How long does IV Ketamine effects last?

5-15 min

How long does it take for the effects of IM Ketamine to kick in?

3-8 min

How long does it take for IM Ketamine to reach peak effect?

5-20 min

How long do the effects of IM Ketamine last?

12-25 min

How long does it take IV Propofol (Diprivan) to kick in?

less than 40 sec

How long does it take for IV Propofol to reach peak effect?

1 min

How long does IV Propofol’s effects last in the body?

5-10 min

What is the appropriate IV Propofol dosage for an adult?

25-50 mg (0.5-1 mg/kg) IV, administered in 10 mg increments over several minutes. Pain on injection is decreased with IV lidocaine (0.1 mg/kg added to the diprivan emulsion)

What are the adverse reactions of Ketamine?

Respiratory - resp depression, apnea, hiccup, bronchospasm, laryngospasm

Cardiovascular fx - hotn, arrhythmia, tachycardia, bradycardia, htn

CNS fx - headache, dizziness, euphoria, myoclonic/clonic movement, seizures, sexual illusions