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What does ANS stand for?
Autonomic nervous system
Main divisions of ANS?
Sympathetic and parasympathetic
What does the somatic nervous system innervate?
Skeletal muscle
How many neurons connect CNS to effector in ANS?
Two neurons
First ANS neuron called?
Preganglionic neuron
Second ANS neuron called?
Postganglionic neuron
Where is the postganglionic neuron cell body located?
Ganglion
Does somatic motor neuron synapse in ganglion?
No
Main neurotransmitter of parasympathetic system?
Acetylcholine
Main neurotransmitter of sympathetic system?
Norepinephrine
Other sympathetic neurotransmitters?
Epinephrine and dopamine
Main role of sympathetic system?
Fight or flight
Main role of parasympathetic system?
Rest and digest
Sympathetic system prepares body for?
Stress and emergencies
Parasympathetic system promotes?
Storage and conservation
Effect of sympathetic stimulation on heart rate?
Increases
Effect of sympathetic stimulation on contractility?
Increases
Effect of sympathetic stimulation on skeletal muscle blood flow?
Increases
Effect of sympathetic stimulation on skin blood flow?
Decreases
Effect of sympathetic stimulation on GI activity?
Decreases
Effect of sympathetic stimulation on GI sphincters?
Contracts
Effect of sympathetic stimulation on bronchi?
Bronchodilation
Effect of sympathetic stimulation on pupils?
Dilation
Effect of sympathetic stimulation on urinary bladder sphincter?
Contraction
Effect of sympathetic stimulation on anal sphincter?
Contraction
Male genital sympathetic function?
Ejaculation
Male genital parasympathetic function?
Erection
Effect of sympathetic stimulation on glycogen?
Breakdown
Effect of sympathetic stimulation on blood glucose?
Increases
Effect of sympathetic stimulation on adipose tissue?
Lipolysis
Effect of parasympathetic system during digestion?
Activates GI tract
What pupil change aids near vision?
Constriction
Which ANS division dominates during rest?
Parasympathetic
Three major sites of PNS neurotransmission?
Ganglia neuroeffector junctions NMJ
Neurotransmitter at all autonomic ganglia?
Acetylcholine
Neurotransmitter at skeletal NMJ?
Acetylcholine
Major neurotransmitter at sympathetic neuroeffector junctions?
Norepinephrine
Neurons releasing acetylcholine are called?
Cholinergic neurons
Neurons releasing norepinephrine are called?
Adrenergic neurons
Are all sympathetic postganglionic neurons adrenergic?
No
Sympathetic fibers to sweat glands release?
Acetylcholine
Sympathetic fibers to some skeletal muscle vessels release?
Acetylcholine
Drugs mimicking acetylcholine are called?
Cholinomimetics
Other name for cholinomimetics?
Parasympathomimetics
Drugs mimicking norepinephrine are called?
Adrenomimetics
Other name for adrenomimetics?
Sympathomimetics
Receptors for acetylcholine are called?
Cholinoceptors
Receptors for norepinephrine are called?
Adrenoceptors
Drugs blocking acetylcholine are called?
Cholinoceptor antagonists
Drugs blocking norepinephrine are called?
Adrenoceptor antagonists
Most visceral organs receive what type of innervation?
Dual innervation
How do sympathetic and parasympathetic systems usually act?
Oppositely
Example of organ with opposing same-cell effects?
SA node
Example of organ with opposing different-cell effects?
Iris muscles
Most blood vessels are innervated by which system?
Sympathetic
Exceptions with dual vessel innervation?
Face tongue urogenital tract
Primary neural control of TPR?
Sympathetic nerves
What controls vascular caliber tonically?
Noradrenergic neurons
Heart is innervated by?
Both ANS divisions
Sympathetic effect on heart rate?
Positive chronotropic
Sympathetic effect on contractility?
Positive inotropic
Sympathetic effect on AV conduction?
Positive dromotropic
Parasympathetic effect on heart rate?
Negative chronotropic
Parasympathetic effect on AV conduction?
Negative dromotropic
Parasympathetic effect on atrial contractility?
Decreases
Parasympathetic effect on ventricular contractility?
Minimal
Heart at rest is mainly under?
Vagal tone
Effect of ganglionic blockers at rest?
Increase heart rate
Effect of ganglionic blockers during exercise?
Decrease heart rate
What do ganglionic blockers inhibit?
Both autonomic ganglia
What controls pupil size?
ANS
Muscle causing mydriasis?
Dilator pupillae
Innervation of dilator pupillae?
Sympathetic
What is mydriasis?
Pupil dilation
Muscle causing miosis?
Constrictor pupillae
Innervation of constrictor pupillae?
Parasympathetic
What is miosis?
Pupil constriction
Which ANS division dominates the eye?
Parasympathetic
Effect of atropine on pupil?
Mydriasis
Effect of atropine on accommodation?
Loss
What drug blocks parasympathetic activity in eye?
Atropine
Effect of parasympathetic stimulation on accommodation?
Near vision
What type of muscle controls pupil diameter?
Smooth muscle
What are radial iris muscles called?
Dilator pupillae
What are circular iris muscles called?
Constrictor pupillae
Effect of sympathetic stimulation on respiratory tract?
Bronchodilation
Effect of parasympathetic stimulation on GI tract?
Increased activity
Which ANS division contracts sphincters?
Sympathetic
What neurotransmitter is released at all preganglionic fibers?
Acetylcholine
Most postganglionic parasympathetic fibers release?
Acetylcholine
Most postganglionic sympathetic fibers release?
Norepinephrine
What is positive chronotropy?
Increased heart rate
What is positive inotropy?
Increased contractility
What is positive dromotropy?
Increased conduction
What is negative chronotropy?
Decreased heart rate
What is negative dromotropy?
Decreased conduction
Sympathetic response to stress?
Resource mobilization
Parasympathetic activity predominates during?
Minimal stress
Which ANS division increases blood fatty acids?
Sympathetic
Which ANS division increases blood sugar?
Sympathetic