Module 1 - Names in History

Pen Tsao

Earliest compilation

of drugs, which was

written by Emperor

Shengnung in about

2,700 B.C.

Pen Tsao

describe penalties

for malpractices of

practitioner

Code of Hammurabi 

describe penalties

for malpractices of

practitioner

Kahun papyrus 

oldest record of

Egyptian drugs

Ebers papyrus 

compilation of ds.

conditions and

prescriptions

Ashurbanipal

assembled the

library of clay

tablets in Sumeria

Hippocrates 

 “father of medicine”

- greatest teacher of

medicine

Vis medicatrix nature

concept of the healing power of

nature

Aristotle

formed the

scientific basis of

medicine

Theophrastus

systemically

classifies medicinal

plants

Carolus Linnaeus 

established the

modern scientific

method of naming

plants or animals

Carolus Linnaeus 

Father of Taxonomy.

Dioscorides 

complied the 1st

materia medica

(old subject of

pharmacology),

study of plants, how

it is extracted and its

uses.

Galen

deals with

physiology and

material medica

Publius Vegetius 

compiled a treatise

that included

prescriptions for

farm animals

Geber Ibn Hjar 

classified drugs and

poison

Valerius cordus 

compiled the 1st

pharmacopeia

William Harvey 

discovered the

circulation of blood

and indicated that drug were

distributed to

various parts of the

body by this means

Christopher Wren 

1630, make the 1st

I.V. injection of

drugs into a dog

Alexander Wood

1850, devised the 1st

hypodermic needle

and syringe

Theoprastus Bombastus Von Hohenheim

introduced the

clinical use of

opium or laudanum

Theoprastus Bombastus Von Hohenheim

Also called himself

Philippus Aureolus

Paracelsus

Fredrich Serturner 

isolated the narcotic substance of opium and called it morphine after the Roman God of Dream, Morpheus

Edward Jenner 

Discovered the

vaccine against

Small pox

Francois Magendie

established the foundation for modern pharmacology (drug action, D-R. relationship, drug disposition)

Williiam Withering 

observed the use of foxglove in the Tx of dropsy

Claude Bernard 

showed the active ingredient of foxglove (for anasarca edema), called digitalis

Rudolph Buchheim 

“father of Pharmacology”

Rudolph Buchheim 

• established the 1st independent laboratory devoted exclusively to the study of pharmacology

John Abel 

“Father of Pharmacology in U.S”

Paul Ehrlich 

“Father of chemotherapy”

Paul Ehrlich 

• 1910, reported the synthesis of arsphenamine which in an anti- syphilitic drug, for STD. 3-2024|3rd Semester

• anti-trypanosomal drug, for blood parasite)

• 1st antibacterial drug processing specific for invading pathogens

Alexander Fleming

1928, isolated Penicillin

Gerhard Domagk

1935, isolated sulfonamides

Doisy and Butenandt 

isolated estrone/estrogen from female urine

Butenandt

isolated aldosterone from male urine

Slotta

discovered the steroid structure of progesterone

Kendall

isolated Thyroxine

Harrington

established the chemical structure of thyroxine

Banting & Best 

1922, isolated and purify insulin

John Abel 

isolated adrenaline

Ignaz Semmelweis

antiseptic effect of chlorine in the effect of chlorine in the form of chlorinated lime

Joseph Lister 

use antiseptic in the field of surgery, use carbolic lotion

Adolph von Baeyer 

synthesized barbituric acid

Felix Hoffman 

introduced the use of aspirin