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Artificial Intelligence
Current Trends 3T25-26
Artificial intelligence coined
The term “artificial intelligence” (AI) was coined in the 1950s
Artificial intelligence definition #1
Idea of building machines capable of performing tasks normally performed by humans
Artificial intelligence definition #2
Machines capable of performing human tasks
Machine learning definition
A subdomain of AI that learns intrinsic statistical patterns in data to cast predictions on unseen data
Deep learning definition
Machine learning technique using multi-layer mathematical operations for learning and inferring on complex data like imagery
Popular ML model
Neural networks (NNs)
Neural networks advantage
Outperform classical ML algorithms on complex data structures such as imagery or language
Main constituent of NN
Artificial neuron
Artificial neuron definition
Mathematical non-linear model inspired by the human neuron
How neural networks are engineered
By stacking and concatenating artificial neurons and connecting layers using mathematical operations
Purpose of engineered neural networks
Solve specific tasks like image classification
Example of image classification
Radiographic image showing a decayed tooth: yes or no
Natural intelligence workflow
Perception → Interpretation → Response
Software 1.0 workflow
Data and rules → Explicit programming → Interpretation and actions of human agents
Software 2.0 machine learning workflow
Data and outcomes → Engineered features → Feature mapping → Interpretation and actions of human agents
Software 2.0 deep learning workflow
Data and outcomes → Feature learning and mapping → Interpretation and actions of human agents
Goals of AI-based applications in dentistry
Streamline care; Relieve workforce from laborious routine tasks; Increase health at lower costs; Facilitate personalized, predictive, preventive, and participatory dentistry
Value of AI applications in dentistry
Improving access to and quality of care
Another value of AI in dentistry
Increasing efficiency and safety of services
Another value of AI in dentistry #2
Empowering and enabling patients
Another value of AI in dentistry #3
Supporting medical research or increasing sustainability
Important ethical considerations in dental AI
Individual privacy, rights, and autonomy
Possible solution to privacy concerns
Shift from centralized to distributed/federated learning
Benefit of federated learning
Improves scalability and robustness
Requirement for dental AI solutions
Trustworthiness and generalizability need to be guaranteed
How trustworthiness is maintained
Continuous human oversight and standards grounded in evidence-based dentistry
Explainable AI definition
Methods to visualize, interpret, and explain the logic behind AI solutions
Main reason AI not routine in dentistry
Limited data availability, accessibility, structure, and comprehensiveness
Another limitation of dental AI
Lacking methodological rigor and standards in development
Another limitation of dental AI #2
Practical questions around value and usefulness
Another limitation of dental AI #3
Ethics and responsibility
AI history milestone #1
1943 – Artificial neuron
AI history milestone #2
1957 – Neural networks
AI history milestone #3
1960s – First AI winter
AI history milestone #4
1980s – Rule-based expert systems
AI history milestone #5
1990s – Second AI winter
AI history milestone #6
2006 – Deep learning
AI history milestone #7
2012 – Computer vision leverages neural networks
AI history milestone #8
2015 – AI-based systems outperform human experts in image classification
AI history milestone #9
2015/16 – AlphaGo defeats world-best Go players
AI history milestone #10
2018 – Sundar Pichai compares impact of AI with disruptiveness of electricity and fire
Machine learning definition in AI history
Learning intrinsic statistical patterns and structures in data allowing predictions for unseen data
Deep learning definition in AI history
Form of machine learning using multi-layered deep neural networks trained to learn features of complex data structures
AI history characterization
Characterized by ups and downs
Current optimism in AI
Optimism is greater today than ever before
Applications of AI in dentistry
Image analysis; Prediction making; Record keeping; Dental research and discovery
Dental education role in AI
Foster digital literacy in future dental workforce
AI in dentistry now sample size
Largely under 2,000 instances/images
AI in dentistry future sample size
Millions of multi-level connected instances
Current AI data sources
Single hospitals; Insurance claims data
Future AI data sources
Federated learning; Data from multiple institutions
Current AI focus
Detection of structures on imagery; Association modelling
Future AI focus
Multi-class detection of pathologies; Predictive modelling; Decision support
Current AI training mode
Supervised learning
Future AI training mode
Unsupervised or semi-supervised learning
Current AI testing mode
Cross-validation
Future AI testing mode
Hold-out test set; Independent datasets
Current AI metrics
Measures of accuracy such as accuracy, area-under-the-curve, F1-score, segment overlap
Future AI metrics
Measures of value including impact on treatment decision, clinical and patient-reported outcomes, cost-effectiveness, and trustworthiness
Current AI study types
Diagnostic accuracy studies on retrospectively collected data
Future AI study types
Randomized controlled trials or large cohort studies collecting data prospectively
Black box AI model example
Deep neural network classifies image as “rooster”
Explain prediction method
Backward redistributing output to input
Correct image classification example #1
Image classified as rooster because of rooster’s comb and wattles
Correct image classification example #2
Image classified as cat because of cat’s ears and nose
Incorrect image classification example
Image classified as horse because of a copyright tag
Reference for AI in dentistry
https://journals.sagepub.com/doi/full/10.1177/0022034520915714