ID Exam 3: Laux STIs TREATMENT/info to memorize only

Herpes Simplex Treatment-Initial Occurence

-____ x 7-10 days

-____ x 7-10 days

-_____ x 7-10 days

acyclovir, famciclovir, valacyclovir

Herpes Simplex Treatment-Recurrent Outbreak

-____ x 3-5 days

-____ x 3-5 days

-_____ x 3-5 days

acyclovir, famciclovir, valacyclovir

Herpes Simplex Treatment-Suppressive Therapy

-____ (no set duration)

-____ (no set duration)

-_____ (no set duration)

acyclovir, famciclovir, valacyclovir

Herpes Simplex Treatment-Suppressive Therapy

-all regimens reduce recurrence by 75%

-all regimens are continued for __ year and then re-evaluated

-treatment for up to 1 years with acyclovir and 6 year with valacyclovir or famcyclovir have been evaluated

1

Herpes Simplex Treatment

-some studies indicate that chronic ___ therapy is preferred over episodic treatment

suppressive

Herpes Simplex Treatment

-suppressive therapy combined with consistent ____ protection (e.g., condoms) significantly reduces transmission risk.

barrier

Gonorrhea Treatment-Memorize

-Uncomplicated: ____ 500mg x once IM (if patient is >150kg, dose is 1g IM)

ceftriaxone

Gonorrhea Treatment-Memorize

-Concomitant Chlamydia: _____ 500mg x once AND _____ x 100mg BID x 7 days

ceftriaxone, doxycycline

Gonorrhea Treatment

-If ceftriaxone not available/oral therapy needed: ____ 800mg PO x once

cefixime

Gonorrhea Treatment

-If cephalosporin allergy: ____ 240mg IM + ____ PO

gentamicin, azithromycin

Gonorrhea Treatment

-regimens for gonorrhea may also include treatment for C. ____ (which is doxycycline)

trachomitis

Gonorrhea Treatment

-If patient was not treated with a cephalosporin, or in pharyngeal cases, repeat testing __-__ weeks after treatment to ensure eradication

1-2

Gonorrhea Treatment

If patient has disseminated opthalmic gonorrhea: ____ 1g IV/IM Q24h x 1-2 days after clinical improvement then PO treatment with ___ 400mg BID x 7 days

ceftriaxone, cefixime

Chlamydia Treatment

-____ 100mg BID x 7

-____ 1gm PO x once

-_____ 500mg QD x 7

doxycycline, azithromycin, levofloxacin

Syphilis-3 phases

-syphilus is ____ in the primary and secondary phases

transmissible

Syphilis Treatment-Memorize

-If primary/secondary phase (<1 year): 2.4 million units ____ ___ x once

benzathine penicillin

Syphilis Treatment-Memorize

-use benzathine penicillin formulation Bicillin L-A, NOT Bicillin __-_

C-R

Syphilis Treatment-Memorize

-If primary/secondary phase (<1 year) + PCN allergy: ___ 100mg q12h x 2 weeks OR ____ 500mg q6h x 2 weeks

doxycycline, erythromycin

Syphilis Treatment-Memorize

-If tertiary phase (<1 year): 2.4 million units ____ ___ weekly for 3 doses

benzathine penicillin

Syphilis Treatment-Memorize

-If tertiary phase (<1 year) + PCN allergy: ____ q12 x 4 weeks

doxycycline

Syphilis Treatment

-If neurosyphilis/Gumma phase: ___ ___x 14 days OR ___ ___ + ____ x 14 days

penicillin G, procaine penicillin, probenecid

Syphilis Treatment

-important to note that neurological damage will not be __

reversed

PID Treatment-Severe Case (based on C&S)

1. ____ or ____ AND ____

cefoxitin, cefotetan, doxycycline

PID Treatment-Severe Case (based on C&S)

2. ____ AND ___

clindamycin, gentamicin

PID Treatment-Severe Case (based on C&S)

3. ___/___ AND ____

ampicillin/sulbactam, doxycycline

PID Treatment-Severe Case

-duration of treatment is __-__ days

7-14

PID Treatment

-If mild case/can be treated outpatient, use _____ PO

moxifloxacin

Bacterial Vaginosis Treatment

-___ PO BID x 7 days

-____ gel x 5 days

-____ cream x 7 days

metronidazole, metronidazole, clindamycin

Trichomoniasis Diagnosis-Memorize

-test for ____ is accurate, but there are many false negatives in ___

females, males

Trichomoniasis Treatment

-____ x 7 days

metronidazole

HPV Vaccine-Memorize

-indicated for females aged __-__

9-45

HPV Vaccine-Memorize

-indicated for males aged __-__ (up to 45 if HIV or if having sex with another man)

9-21

HPV Vaccine-Memorize

-for maximum efficacy, begin HPV vaccine ___ onset of sexual activity

before

HPV Vaccine Frequency-Memorize

-if given age 9-14 → __ dose series (0, 6 months)

2

HPV Vaccine Frequency-Memorize

-if given age 15+ → __ dose series (0, 1, 6 months)

3

Chancroid Treatment (based on C&S)

-___ PO x once

-____ IM x once

-____ PO x 3 days

-____ PO x 7 days

azithromycin, ceftriaxone, ciprofloxacin, erythromycin

Lymphogranuloma venereum Treatment

-Buboe surgical ___

-___ x 21 days

-___ x 21 days

drainage, doxycycline, erythromycin

Mycoplasma genitalium Treatment

-___ followed by ___

doxycycline, azithromycin

Mycoplasma genitalium Treatment

-If macrolide resistance: ___ followed by ___

doxycycline, moxifloxacin

Granuloma inguinale treatment

-___

-___

-___

-___

-___/___

azithromycin, doxycycline, ciprofloxacin, erythromycin, smx/tmp

Shigella Flexneri Treatment-Supportive Therapy is usually sufficient

-___, electrolytes, antinausea meds (not anti-motility meds)

fluids

Shigella Flexneri Treatment-If severe/long lasting, use:

-__ gen cephalosporins

-___

-___

-___

-___

3rd, ampicillin, doxycycline, azithromycin, fluoroquinolones

Pediculosis Pubis Treatment

-_____ (apply and wash off after 10 min)

-____ (apply and wash off after 10 min)

permethrin, pyrethrins