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Name 3 indications for oxygen therapy
-Treat hypoxemia
-Decrease work of breathing
-reduce myocardial workload
name 3 ways to assess oxygen levels?
-PaO2
-SpO2
-SaO2
name 4 major hazards of oxygen delivery
-O2 toxicity
-Oxygen Induced hypoventilation (hypoxic drive)
-Retinopathy of Prematurity
-Absorption atelectasis (nitrogen washout)
If a patient is confused, tachypneic, and tachycardic could we suspect hypoxemia?
yes
Refers to cellular injury of lung parenchyma & airway epithelium
Oxygen Toxicity
to prevent O2 toxicity, extended exposure to FiO2 > _________% should be avoided
60%
O2 toxicity may lead to...
ARDS
True or False: In oxygen therapy, we aim to use as little oxygen as possible
True
what patients are at risk of oxygen induced hypoventilation?
COPD patients
give the desired PaO2 and SpO2 ranges for COPD
PaO2= 55-65, SpO2= 88-92
Retinopathy of Prematurity is caused by PaO2 > _______ mmHg in premature infants
80 mmHg
What is the desired PaO2 range for premature infants?
50-80 mmHg
alveolar collapse due to nitrogen washout is called...
Absorption atelectasis
Absorption atelectasis is caused by reduced ____________ in the lung
Nitrogen
why does reduced nitrogen in the lung cause atelectasis?
It reduces production of surfactant
True or False: Oxygen is flammable
FALSE: Oxygen is NOT a flammable gas but it does support combustion
How does excessive oxygen affect ciliary activity?
Decreases ciliary movement
Name 3 basic oxygen delivery design systems
-Low-flow systems
-High-flow systems
-Reservoir systems
O2 DEL system with fixed flow rates and provides only a portion of the patient's ventilatory requirements
Low-flow systems
O2 DEL system with fixed performance and provides ALL of the patients inspiratory requirements at a specific FiO2, regardless of the flow rate or patients ventilatory pattern
High-flow systems
which O2 DEL system will have variable results in performance based on the patients inspiratory effort, tidal volume, respiratory rate
Low-flow systems
O2 DEL system designed to conserve oxygen
Reservoir system
Give the LPM and FiO2 range for nasal cannula
1-6 LPM; 24-44% FiO2
True or False: on a nasal cannula, the FiO2 depends on how much room air the patient inhales in addition to the supplied O2
True
device surgically placed in the neck by a physician; clogs easily and must be cleaned with a cleaning rod
Trantracheal Catheter
what is the LPM and FiO2 range for a simple mask?
5-10 LPM; 40%-60% FiO2
give the LPM and FiO2 range for nonrebreathers
10-15 LPM; 80-100% FiO2
give the LPM and FiO2 range for partial rebreathers
10-15 LPM; 60-80% FiO2
these devices supply oxygen at flows equaling or exceeding the patient's peak inspiratory flow
high flow devices
O2 DEL system most suitable for patients requiring a precise FiO2 or with a variable minute ventilation
High-flow systems
a patient has a variable minute ventilation and requires a precise FiO2. Reccomend a specific O2 DEL device.
Venturi Mask
True or False: Increasing the flow on a high flow device WILL increase the FiO2
FALSE: Increasing the flow on a high flow device WILL NOT affect the FiO2
what 2 factors determine the FiO2 on a Venturi Mask?
-Jet Size
-Entrainment Port size
the larger the air entrainment port, the ______________ (higher, lower) the FiO2
lower
the smaller the air entrainment port, the ______________ (higher, lower) the FiO2
higher
the larger the jet size, the ___________ (more/less) air entrained, thus _____________ (higher/lower) FiO2
less, higher
the smaller the jet size, the ___________ (more/less) air entrained, thus _____________ (higher/lower) FiO2
more, lower
if the air entrainment port became occluded (by the patients hand) how would the FiO2 be affected?
FiO2 would increase (because less air is entrained)
what is the air to oxygen ratio formula?
100-X/X-20* (21 if FiO2 is less than 40%)
O2 DEL device that provides high FiO2, high relative humidity, and positive pressure (i.e optiflow, airvo)
high flow nasal cannula
supplemental oxygen is indicated when __________ is suspected
hypoxemia
the higher the FiO2, the _________ (higher/lower) the air:oxygen ratio
lower
O2 DEL device that delivers 100% FiO2 often during emergencies
bag-mask device
what is the second lightest gas?
helium
helium mixed with oxygen is called...
heliox
what is the main benefit of heliox?
lower density thus the gas can pass through obstructions more easily
what color is a heliox cylinder?
brown and green
give the 2 heliox:oxygen ratios and their correction factors
80:20, 1.8
70:30, 1.6
why must we multiply the heliox flow rate by a correction factor?
because heliox is less dense than oxygen
you're running an 80:20 heliox mixture through an O2 flow meter at 10 L/min. calculate the true flow rate
10 x 1.8= 18 L/min
you're running a 70:30 heliox mixture through an O2 flow meter at 10 L/min. Calculate the true flow rate.
10 x 1.6= 16 L/min
Heliox mixtures must be delivered through a tightly closed system. Name 3 devices suitable for heliox mixtures.
-Nonrebreather
-ET tube
-Trach tube
selective pulmonary vasodilator indicated for ARDS and PPHN
inhaled nitric oxide
what does the X stand for in the air:O2 formula?
FiO2%
fluid that regulates body temperature and maintains the pH of bodily fluids
blood
how many g/dL of reduced hemoglobin will cause cyanosis?
at least 5 g/dL
the point at which 50% of hemoglobin is saturated with oxygen
p50
what is the approximate p50?
27 mmHg
what are the 2 ways oxygen is carried in blood?
-dissolved in plasma
-attached to hemoglobin
formula for oxygen bound to hemoglobin
1.34 x Hb x SaO2
formula for hemoglobin dissolved in plasma
0.003 x PaO2
name the 4 types of hypoxia
-hypoxemic hypoxia
-anemic hypoxia
-stagnant (circulatory) hypoxia
-histotoxic hypoxia
hypoxia caused by lack of O2 in the blood as a result of alveolar hypoventilation, inadequate O2 in inspired air, diffusion defects, V/Q mismatch, and anatomic right to left shunt
hypoxemic hypoxia
when the bloods capacity to carry O2 is reduced as a result of decreased hemoglobin level or CO poisoning
Anemic hypoxia
what kind of hypoxia is CO poisoning?
anemic hypoxia
what diagnostic tool should be recommended for suspected CO poisoning?
ABG with co-oximetry
when the O2 content and carrying capacity is normal, but capillary perfusion is diminished as a result of decreased heart rate, decreased cardiac output, shock, or embolism
Stagnant (circulatory) hypoxia
what kind of hypoxia is caused by cyanide/alcohol poisoning?
histotoxic hypoxia
name 2 conditions for which hyperbaric oxygen therapy is indicated
-cyanide poisoning
-air embolism
name the 2 kinds of O2 analyzers
-Galvanic O2 analyzers
-Polargraphic O2 analyzers
what are the 3 functions of the nose?
warming, filtering, and humidifying inspired air
at what anatomical point is inspired air 100% saturated with water?
the carina
at the carina, what temperature is inspired air warmed to?
37 C (body temperature)
suspension of water in a particle form in gas
aerosol
what is the ideal particle size range of aerosols?
1-5 microns