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mutation definition
changes in sequence of nucleotides in DNA
insertion/deletion mutation
when one or more nucleotide are inserted/deleted from sequence
frameshift: alters the sequence after insertion/deletion.
point mutation
one base pair replaced by another
nonsense mutation
adds a stop codon, translation stops
missense mutation
nucleotide change alters codon = codes for a diff AA.
alters tertiary structure
silent mutation
codon change that doesn't affect AA
could be due to degenerate nature
leaves primary structure unchanged