Pollev

The glycocalyx on the outer surface of the plasma membrane:

can mediate cell-to-cell and cell-substratum interactions

Which of the following statements about integrins is true?

They anchor cells to the substrate

Evidence strongly suggests that the bent conformation of an integrin is _______ and unable to bind its ligand.

inactive

Which structure is NOT part of the endomembrane system?

chloroplast

A protein is transported in a secretory vesicle and discharges into the extracellular space in a continuous fashion. What type of secretion is this?

constitutive

The signal sequence is found at the N-terminus of:

secretory proteins

To be imported into a mitochondrion or chloroplast, proteins must be

unfolded or extended

Where are misfolded secretory proteins eventually destroyed? Select answer from the options below

in the cytosol (cytoplasm)

The smooth endoplasmic reticulum is responsible for all of the following EXCEPT:

protein modifications

How do integral membrane proteins enter the lipid bilayer?

The aqueous translocon channel has a gate that continuously opens and closes, giving each nascent polypeptide segment a chance to partition itself into the lipid bilayer's hydrophobic core.

Molecular chaperones in the rough ER:

bind to misfolded proteins and help them to fold into their correct three-dimensional shape

What determines the sequence of sugar addition to glycoproteins traveling through the Golgi complex?

the spatial arrangement of specific glycosyltransferases that contact proteins as they pass through the Golgi

Vesicles that move through the Golgi complex from a trans-donor to a cis-acceptor membrane are said to move in a(n) direction.

retrograde

Which of the following processes does NOT take place in the Golgi complex? Select answer from the options below

digestion of misfolded proteins

Which coated vesicles move materials in an anterograde direction from the ER toward the ERGIC and Golgi stack?

COPII-coated vesicles

Which of the following statements about lysosomes is FALSE?

Each different lysosome contains a single unique lysosomal enzyme.

Which of the following statements about autophagy is FALSE?

It increases the incidence of cancer and the rate of aging.