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The Chain of Infection
Infectious Agent: Bacteria, viruses, fungi, or protozoa.
Reservoir: Where pathogens survive (e.g., food, water, oxygen, or human hands).
Portal of Exit: How the pathogen leaves (e.g., skin, respiratory tract, urinary tract, blood).
Mode of Transmission: Often the hands of healthcare workers. Routes include contact, droplet, or airborne.
Portal of Entry: Same routes as exiting.
Susceptible Host: Patients with invasive procedures (IVs, surgery) or who are immunocompromised (transplant patients, newborns, or premature infants).
Identification & Testing
Specimens: Collected from sputum, blood, drainage, or urine (Urinalysis).
Sensitivity Testing: Once the culture is grown, clinicians find which antimicrobials the organism is sensitive to for precise medication selection.
Airborne
Measles, Varicella, Herpes Zoster (Shingles)
private room; negative-pressure airflow.
N95 Respirator.
Droplet
Influenza (Flu), Pertussis, RSV
Private room or cohort patients
Mask or respirator.
Contact
MRSA, VRE, C. diff, Scabies
Private room or cohort patients.
Gloves and Gown.
Contact (+)
C. diff
Must use soap and water for hand hygiene (Standard knowledge; sources specify "contact +").
Gloves and Gown.
Infectious Disease
AIDS, COVID-19, STIs, Pneumonia
Standard/Transmission precautions as indicated by symptoms.
Standard/Transmission precautions as indicated by symptoms.
Standard Precautions
used with every patient
hand hygiene
no artifical nails
gloves when touching body fuilds or contaminayed items/surfaces
ppe as needed for procedures
WHO’s Five Moments
1) Before touching a patient,
2) Before clean/aseptic procedures,
3) After body fluid exposure risk,
4) After touching a patient
5) After touching patient surroundings.
Isolation Considerations
Psychological Impact: Isolation can cause loneliness, depression, and anxiety. Nurses must provide emotional support.
Documentation: Infection status and required PPE must be documented and posted outside the room.
Patient Transport: If an isolation patient must leave their room, the patient must wear appropriate PPE (e.g., a mask for droplet).
Absorption:
The passage of medication molecules into the blood.
NURSING SCHOOL MUST KNOW: IV is the fastest route, followed by IM/SQ; skin and oral (PO) routes are the slowest.
Patient Example: Factors like low blood pressure or Congestive Heart Failure (CHF) can impair circulation and slow down absorption.
Distribution
How the drug reaches tissues and organs
Protein Binding: Low albumin levels in a patient can lead to medication toxicity because there is less protein for the drug to bind to.
membrane permeability
Metabolism
Primarily occurs in the liver
NURSING SCHOOL MUST KNOW: Patients with liver failure have impaired metabolism, leading to a high risk of toxicity; they often require lower doses
Excretion
Medications exit the body through the kidneys, liver, bowel, lungs, and exocrine glands.
Need to Know: Impaired kidney function significantly increases the risk for medication toxicity.
Therapeutic Effect
The expected or predicted physiological response.
Adverse Effects:
Unintended and undesirable responses.
Toxic Effect vs side effect
Toxic Effect - Accumulation of medication in the blood
Side Effect - Predictable and unavoidable (e.g., vomiting).
Idiosyncratic Reaction
An unpredictable overreaction or underreaction.
Example: Giving Adderall to help a patient focus, but it causes the opposite effect, such as agitation
Timing of Responses: peak, trough, therapeutic range
Peak: Highest level of the drug in the blood.
Trough: Lowest level of the drug in the blood.
Therapeutic Range: The goal is to keep the plasma drug concentration between the minimum effective concentration (MEC) and the toxic concentration.
The Seven Rights:
1. Medication, 2. Dose, 3. Patient (use two verifiers like name and DOB), 4. Route, 5. Time, 6. Documentation, 7. Indication.
Types of Orders: stat, now, prn
STAT: Give immediately (usually a 30-minute window).
Now: Needed quickly (up to a 90-minute window).
PRN: Given "as needed" based on patient symptoms.
Topical/Skin Applications:
NURSING SCHOOL MUST KNOW: Always wear clean gloves when removing or applying transdermal patches to prevent medication from absorbing into your own skin.
Patient Safety: Always ask if the patient has an existing patch and remove the old patch before applying a new one to prevent a potential overdose.
Documentation: Note the location of the patch on the Medication Administration Record (MAR) and document the removal of the old one.
Nasal Instillation:
Need to Know: Caution patients about the rebound effect—excessive use of decongestant sprays can actually worsen congestion.
Patient Example: In children, serious systemic effects can occur if excess decongestant solution is swallowed.
Ophthalmic (Eye) Instillation:
Safety: Avoid touching the cornea and do not touch the eye or eyelid with the dropper to prevent infection.
Patient Teaching: If using an intraocular disk (which resembles a contact lens), teach the patient how to insert and remove it and monitor for adverse effects.
Otic (Ear) Instillation:
NURSING SCHOOL MUST KNOW: Instill eardrops at room temperature; cold drops can cause vertigo (dizziness) or nausea.
Safety: Use sterile solutions in case the eardrum is ruptured, and never occlude the ear canal with the dropper.
Vaginal and Rectal Instillation:
Vaginal: Inserted with a gloved hand (suppositories) or an applicator (foams/jellies/creams).
Rectal: Rectal suppositories are bullet-shaped to prevent anal trauma.
Patient Example: Use lubrication and place the patient in the left side-lying position for rectal administration.
Inhalation
pMDIs (Pressurized metered-dose inhalers): Require hand-breath coordination.
Need to Know: These are often used with a spacer to help deliver more medication to the lungs, especially for patients with poor coordination.
Equipment Basics - Syringes:
Luer-Lok syringes have threading that allows a needle to be "locked" on, while Non-Luer-Lok syringes use a plain tip.
Preparing Injections - Ampules
NURSING SCHOOL MUST KNOW: You must use a filter needle when withdrawing medication from an ampule to prevent glass shards from being drawn into the syringe.
Preparing Injections - Vials
You must inject air into the vial equal to the amount of medication you intend to withdraw to create the necessary pressure.
mixing insulin
NURSING SCHOOL MUST KNOW: Never mix long-acting insulins (Glargine/Lantus or Detemir/Levemir) with any other types of insulin.
"Clear before Cloudy": When mixing rapid/short-acting (clear) with intermediate (NPH/cloudy), draw the clear insulin into the syringe first.
Intradermal (ID):
Used for skin testing (TB, allergies). Use a 5 to 15-degree angle with the bevel up; a small bleb (bump) should form under the skin.
Subcutaneous (SQ)
Placed into loose connective tissue under the dermis (e.g., insulin). Inject at a 45 to 90-degree angle depending on the patient's weight and the amount of subcutaneous tissue.
Intramuscular (IM):
Faster absorption than SQ. Always inject at a 90-degree angle.
Amounts:
adults: 2 to 5mL
children, other adults, and thin patients: up to 2mL
small children and older infants: up to 1mL
smaller infants: up to 0.5mL
IM Sites:
Ventrogluteal: The safest and preferred site for all adults, children, and infants.
Vastus Lateralis: Frequently used for infants and toddlers.
Deltoid: Used for small volumes (less than 2 mL). It is not well-developed in many adults and is close to major nerves.
Factors Influencing Hygiene Practices
Social & Cultural: Social practices (frequency of bathing), personal preferences (shower vs. bath), and cultural variables.
Socioeconomic Status: Availability of products and facilities.
Body Image: A patient’s subjective view of their own appearance.
Physical Condition:
Arthritis: Affects dexterity, making grooming difficult.
Stroke: Can leave patients with significant physical impairments.
COPD: Patients may experience Shortness of Breath (SOB) during hygiene activities.
Casts: Cannot get wet, requiring specialized care.
Developmental Considerations
Skin: As patients age, the skin starts to thin and becomes easy to break, leading to an increased risk of infection.
Mouth: Considerations for teeth and the presence of dentures.
Nursing School "Must-Knows" & Safety Guidelines
identifiers before beginning care.
Clean to Dirty: Always move from the cleanest areas to the less clean areas to prevent cross-contamination.
Infection Control: Use clean gloves when in contact with non-intact skin, mucous membranes, blood, or any bodily secretions/excretions.
Temperature Safety: Always test the temperature of the water or cleaning solutions before they touch the patient.
Body Mechanics: Use proper body mechanics and safe patient-handling techniques to prevent injury to yourself and the patient.
Delegation: Provide clear and proper direction when delegating hygiene tasks to Nursing Assistive Personnel (NAP).
Patient Room Environment
Bed Making: Do not bring extra linens into the room; keep the environment clean and organized to decrease the risk of falls.
Comfort: Maintain a comfortable room temperature and minimize noise to promote rest.
Health Promotion: Adapt your instructions based on the patient’s knowledge and motivation. Teach them how to avoid injury and reinforce infection control practices they can use at home.
Enteral Nutrition (EN) – Feeding via Tube
Must-Know: Used when a patient has a functional GI tract but cannot swallow (e.g., head/neck cancer, anorexia).
Tube Types: Nasogastric (NG), Gastric, or Jejunal.
Safety & Nursing Care:
Aspiration Risk: Keep the Head of Bed (HOB) at 30° minimum, preferably 45°.
Verification: Check gastric residuals to see how much formula is being absorbed.
Equipment: Use aseptic technique, label all equipment (patient name, formula, rate, time), and always use an infusion pump for continuous feedings.
ENFit: Ensure appropriate ENFit connectors are used to prevent tubing misconnections.
Parenteral Nutrition (PN) – Intravenous Feeding
Must-Know: Provided intravenously for patients unable to digest or absorb enteral nutrition (e.g., severe IBD, fistulas, or when GI rest is required).
Access: Can be delivered via peripheral or central lines.
Complications: Nurses must monitor for occlusion and infection.
Nursing Requirements:
Placement must be confirmed by X-ray before use.
Always use a sterile technique and an infusion pump.
Nursing School "Must-Know" Safety Summary
Standardized Practice: Follow the "right patient, right formula, right tube, right ENFit adapter".
Tubing Safety: Trace all lines back to the patient to ensure enteral-to-enteral connections only.
No Dyes: Do not add food coloring or dye to enteral feedings.
Advancing Diets: Patients in acute care should experience a gradual progression of dietary intake (e.g., clear liquid to full liquid to solid) to manage illness recovery
Nutritional Needs Across the Lifespan
Infants/Children: Focus on breastfeeding, formula, and the gradual introduction of solid foods.
Pregnancy/Lactation:
Folic acid intake is critical for development.
Lactating women require an additional 500 kcal/day above their usual intake.
Older Adults:
Metabolic rate slows with age.
Diminished sensations: Thirst, taste, and smell often decrease, which can lead to poor intake.
Barriers: Fixed income, limited transportation, and general health changes.
Vegetarian Diets: Nurses must monitor for potential deficiencies in protein and Vitamin B12.
pressure injuries
damage to the skin due to unrelieved pressure
found on the bony proviences (butt, heel, elbows, etc)
could be found on those with spinsl cord injuries, diabetes, stroke pt (all due to lack of mobilitiy)
risk factors pressure injuries
impaired sensation or mobility
alteration in LOC
dec awareness and communication skill
shear - opposing force (ex: pts gravity is pulling down, bed is pulling up)
friction - rubbing force
moisture
ischemia
dec blood supply to an area
hyperemia (or erythema)
redness
blanchable
color lightens when pressure applied
non blanchable
stays red (hyperemia) despite pressure application
Non-blanchable erythema is a stage 1 pressure ulcer
PU Classification
stage 1 - non balchable erthmea of intact skin
stage 2 - partial thickness skin loss w exposed dermis
no visble fat (only pink or red)
stage 3 - full thickness skin loss
exposed fat (yellow)
could see sloth (greenish, yellow discharge or black dead eschar)
stage 4 - pressure injury: full thickness skin and tissue loss
to muscle, bone, ligament, tendon
DTPI (deep tissure pressure injury)
granulation tissue - new tissue (pink/red)
slough
eschar
excudate drainage
wound classifications
partial thickness wounds (epidermis, superficial layers)
full thickness wounds (epidermis and dermis)
primary intention - clean, approx/closed edges, edges of wound line up nicely, lower risk of infection (surgical wound, sutured, etc)
secondary intention - edges not approx or line up nicely (ex: road rash, pressure ulcer, wound that got infected)
complications of wound healing
hemorrhage - bleeding
infection - pain, fever, heat to area, yellow pus (purulent), inc redness, odor
dehiscence - opening/seperation of wound layers (intervention: cover it with wet gauze)
evisceration - opens w something coming out
drainage terms (serous, purulent, sanguineous, serosanguinous)
serous - clear, watery, thin fluid
purulent - yellow, thick
sanguineous - blood
serosanguinous - watery, pink or red
prevention injury considerations
prediction and prevention (reposition q2h)
economic consequences (we don’t get paid and it costs money to treat them)
factors influencing pressure injury formation and wound healing
nutrition
tissue perfusion (DM (high bp slow wound healing, PVD (dec circulation)
infection
age (dec function macrophages)
psychosocial impact of wounds
differences between ventilation, perfusion, diffusion
ventilation - movement of gasses into and out od lungs (inhale/exhale)
perfusion - cv system pumps oxygenated bloos to tissues and returns deoxygenated blood to lungs
diffusion - process of exchange of repiratoy gasses in avleoli
alterations in respiratory functining
hypoventilation - RR less than 12
hyperventilation - RR greater than 20
hypoxia - low O2, under 95% room air
modes of O2 delivery (NEED KNOW: CANNULA VS MASK, FLOW RATES)
nasal cannula (1-6L/min, if greater than 4 then humidify
can still eat/talk
hook up to sterile water or saline if greater than 4
6L/min MAX for nasal cannula
high flow nasal cannula - provides heated and humidified O2 via NC
oxygen mask (6-12L/min, want greater than 6 to avoid rebreathing exhaled CO2 in the mask)
partial rebreather and nonrebreather have reservior bags (10-15L/min)
venturi high flow (4-12L/min, usually for COPD)
Physiology of pain
transduction - stimuli
transmission - movement, communication
perception - awareness: brain intercepts/processes
modulation - inhibition of pain impluse
pain scales: numerical rating scale
pt rates pain from 0-10
best used for adults/older children who understand numbers
pain scales: verbal descriptive scale
pt chooses words to describe pain such as no pain, mild, moderate, severe, very severe, worst possible pain
best for pt who have diffficulty using numbers but can describe pain
pain scales: visual analog scale
pt marks their pain on a straight line, usually from “no pain” to “worst pain”. The nurse measures where they marked
pt who can understand visual/spartial concepts
wong baker faces pain rating
pt choose a face that matches their pain lvl, ranging from happy to crying
best for children, patients w language barriers, or pt who respond better to pictures
acute care: pharacological pain therapies
patient controlled analgesia
topical and transdermal analgesics
local anesthesia via injection
lock anesthetic infusion
epidural
analgesics
nonopiods
opiods
adjuvants
WHO 3 step ladder
step 1 - mild pain - non opiod
step 2 - moderate pain - weak opiod
step 3 - severe pain - strong opiod
benner’s stages of nursing proficiency
novice - student, new grad
advanced beginner
competent - 2 to 3 years in setting
proficient - greater than 2 to 3 years
expert - diverse experience
professional responsibilities and roles
autonomy and accountability
care giver - maintain and regain health
advocate - advocate for pt safety
educator
communciator
Manager - established environment
florance nightingale
established first nursing philosophy based on health maintenance and restoration
organized the first school of nursing
First practising epidemiologist
reduced mortality rates
clara barton
red cross
cared for soilders in the civil war