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Last updated 1:32 AM on 6/11/26
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74 Terms

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The Chain of Infection

  • Infectious Agent: Bacteria, viruses, fungi, or protozoa.

  • Reservoir: Where pathogens survive (e.g., food, water, oxygen, or human hands).

  • Portal of Exit: How the pathogen leaves (e.g., skin, respiratory tract, urinary tract, blood).

  • Mode of Transmission: Often the hands of healthcare workers. Routes include contact, droplet, or airborne.

  • Portal of Entry: Same routes as exiting.

  • Susceptible Host: Patients with invasive procedures (IVs, surgery) or who are immunocompromised (transplant patients, newborns, or premature infants).

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Identification & Testing

  • Specimens: Collected from sputum, blood, drainage, or urine (Urinalysis).

  • Sensitivity Testing: Once the culture is grown, clinicians find which antimicrobials the organism is sensitive to for precise medication selection.

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Airborne

  • Measles, Varicella, Herpes Zoster (Shingles)

  • private room; negative-pressure airflow.

  • N95 Respirator.

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Droplet

  • Influenza (Flu), Pertussis, RSV

  • Private room or cohort patients

  • Mask or respirator.

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Contact

  • MRSA, VRE, C. diff, Scabies

  • Private room or cohort patients.

  • Gloves and Gown.

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Contact (+)

  • C. diff

  • Must use soap and water for hand hygiene (Standard knowledge; sources specify "contact +").

  • Gloves and Gown.

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Infectious Disease

  • AIDS, COVID-19, STIs, Pneumonia

  • Standard/Transmission precautions as indicated by symptoms.

  • Standard/Transmission precautions as indicated by symptoms.

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Standard Precautions

used with every patient

  • hand hygiene

  • no artifical nails

  • gloves when touching body fuilds or contaminayed items/surfaces

  • ppe as needed for procedures

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WHO’s Five Moments

1) Before touching a patient,

2) Before clean/aseptic procedures,

3) After body fluid exposure risk,

4) After touching a patient

5) After touching patient surroundings.

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Isolation Considerations

  • Psychological Impact: Isolation can cause loneliness, depression, and anxiety. Nurses must provide emotional support.

  • Documentation: Infection status and required PPE must be documented and posted outside the room.

  • Patient Transport: If an isolation patient must leave their room, the patient must wear appropriate PPE (e.g., a mask for droplet).

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Absorption:

The passage of medication molecules into the blood.

  • NURSING SCHOOL MUST KNOW: IV is the fastest route, followed by IM/SQ; skin and oral (PO) routes are the slowest.

  • Patient Example: Factors like low blood pressure or Congestive Heart Failure (CHF) can impair circulation and slow down absorption.

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Distribution

How the drug reaches tissues and organs

  • Protein Binding: Low albumin levels in a patient can lead to medication toxicity because there is less protein for the drug to bind to.

  • membrane permeability

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Metabolism

Primarily occurs in the liver

  • NURSING SCHOOL MUST KNOW: Patients with liver failure have impaired metabolism, leading to a high risk of toxicity; they often require lower doses

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Excretion

Medications exit the body through the kidneys, liver, bowel, lungs, and exocrine glands.

  • Need to Know: Impaired kidney function significantly increases the risk for medication toxicity.

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Therapeutic Effect

The expected or predicted physiological response.

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Adverse Effects:

Unintended and undesirable responses.

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Toxic Effect vs side effect

Toxic Effect - Accumulation of medication in the blood

Side Effect - Predictable and unavoidable (e.g., vomiting).

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Idiosyncratic Reaction

An unpredictable overreaction or underreaction.

Example: Giving Adderall to help a patient focus, but it causes the opposite effect, such as agitation

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Timing of Responses: peak, trough, therapeutic range

  • Peak: Highest level of the drug in the blood.

  • Trough: Lowest level of the drug in the blood.

  • Therapeutic Range: The goal is to keep the plasma drug concentration between the minimum effective concentration (MEC) and the toxic concentration.

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The Seven Rights:

1. Medication, 2. Dose, 3. Patient (use two verifiers like name and DOB), 4. Route, 5. Time, 6. Documentation, 7. Indication.

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Types of Orders: stat, now, prn

  • STAT: Give immediately (usually a 30-minute window).

  • Now: Needed quickly (up to a 90-minute window).

  • PRN: Given "as needed" based on patient symptoms.

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Topical/Skin Applications:

  • NURSING SCHOOL MUST KNOW: Always wear clean gloves when removing or applying transdermal patches to prevent medication from absorbing into your own skin.

  • Patient Safety: Always ask if the patient has an existing patch and remove the old patch before applying a new one to prevent a potential overdose.

  • Documentation: Note the location of the patch on the Medication Administration Record (MAR) and document the removal of the old one.

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Nasal Instillation:

  • Need to Know: Caution patients about the rebound effect—excessive use of decongestant sprays can actually worsen congestion.

  • Patient Example: In children, serious systemic effects can occur if excess decongestant solution is swallowed.

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Ophthalmic (Eye) Instillation:

  • Safety: Avoid touching the cornea and do not touch the eye or eyelid with the dropper to prevent infection.

  • Patient Teaching: If using an intraocular disk (which resembles a contact lens), teach the patient how to insert and remove it and monitor for adverse effects.

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Otic (Ear) Instillation:

  • NURSING SCHOOL MUST KNOW: Instill eardrops at room temperature; cold drops can cause vertigo (dizziness) or nausea.

  • Safety: Use sterile solutions in case the eardrum is ruptured, and never occlude the ear canal with the dropper.

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Vaginal and Rectal Instillation:

  • Vaginal: Inserted with a gloved hand (suppositories) or an applicator (foams/jellies/creams).

  • Rectal: Rectal suppositories are bullet-shaped to prevent anal trauma.

  • Patient Example: Use lubrication and place the patient in the left side-lying position for rectal administration.

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Inhalation

pMDIs (Pressurized metered-dose inhalers): Require hand-breath coordination.

Need to Know: These are often used with a spacer to help deliver more medication to the lungs, especially for patients with poor coordination.

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Equipment Basics - Syringes:

Luer-Lok syringes have threading that allows a needle to be "locked" on, while Non-Luer-Lok syringes use a plain tip.

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Preparing Injections - Ampules

NURSING SCHOOL MUST KNOW: You must use a filter needle when withdrawing medication from an ampule to prevent glass shards from being drawn into the syringe.

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Preparing Injections - Vials

You must inject air into the vial equal to the amount of medication you intend to withdraw to create the necessary pressure.

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mixing insulin

  • NURSING SCHOOL MUST KNOW: Never mix long-acting insulins (Glargine/Lantus or Detemir/Levemir) with any other types of insulin.

  • "Clear before Cloudy": When mixing rapid/short-acting (clear) with intermediate (NPH/cloudy), draw the clear insulin into the syringe first.

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Intradermal (ID):

Used for skin testing (TB, allergies). Use a 5 to 15-degree angle with the bevel up; a small bleb (bump) should form under the skin.

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Subcutaneous (SQ)

Placed into loose connective tissue under the dermis (e.g., insulin). Inject at a 45 to 90-degree angle depending on the patient's weight and the amount of subcutaneous tissue.

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Intramuscular (IM):

Faster absorption than SQ. Always inject at a 90-degree angle.

  • Amounts:

    • adults: 2 to 5mL

    • children, other adults, and thin patients: up to 2mL

    • small children and older infants: up to 1mL

    • smaller infants: up to 0.5mL

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IM Sites:

  • Ventrogluteal: The safest and preferred site for all adults, children, and infants.

  • Vastus Lateralis: Frequently used for infants and toddlers.

  • Deltoid: Used for small volumes (less than 2 mL). It is not well-developed in many adults and is close to major nerves.

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Factors Influencing Hygiene Practices

  • Social & Cultural: Social practices (frequency of bathing), personal preferences (shower vs. bath), and cultural variables.

  • Socioeconomic Status: Availability of products and facilities.

  • Body Image: A patient’s subjective view of their own appearance.

  • Physical Condition:

    • Arthritis: Affects dexterity, making grooming difficult.

    • Stroke: Can leave patients with significant physical impairments.

    • COPD: Patients may experience Shortness of Breath (SOB) during hygiene activities.

    • Casts: Cannot get wet, requiring specialized care.

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Developmental Considerations

  • Skin: As patients age, the skin starts to thin and becomes easy to break, leading to an increased risk of infection.

  • Mouth: Considerations for teeth and the presence of dentures.

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Nursing School "Must-Knows" & Safety Guidelines

  1. identifiers before beginning care.

  2. Clean to Dirty: Always move from the cleanest areas to the less clean areas to prevent cross-contamination.

  3. Infection Control: Use clean gloves when in contact with non-intact skin, mucous membranes, blood, or any bodily secretions/excretions.

  4. Temperature Safety: Always test the temperature of the water or cleaning solutions before they touch the patient.

  5. Body Mechanics: Use proper body mechanics and safe patient-handling techniques to prevent injury to yourself and the patient.

  6. Delegation: Provide clear and proper direction when delegating hygiene tasks to Nursing Assistive Personnel (NAP).

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Patient Room Environment

  • Bed Making: Do not bring extra linens into the room; keep the environment clean and organized to decrease the risk of falls.

  • Comfort: Maintain a comfortable room temperature and minimize noise to promote rest.

  • Health Promotion: Adapt your instructions based on the patient’s knowledge and motivation. Teach them how to avoid injury and reinforce infection control practices they can use at home.

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Enteral Nutrition (EN) – Feeding via Tube

Must-Know: Used when a patient has a functional GI tract but cannot swallow (e.g., head/neck cancer, anorexia).

  • Tube Types: Nasogastric (NG), Gastric, or Jejunal.

  • Safety & Nursing Care:

    • Aspiration Risk: Keep the Head of Bed (HOB) at 30° minimum, preferably 45°.

    • Verification: Check gastric residuals to see how much formula is being absorbed.

    • Equipment: Use aseptic technique, label all equipment (patient name, formula, rate, time), and always use an infusion pump for continuous feedings.

    • ENFit: Ensure appropriate ENFit connectors are used to prevent tubing misconnections.

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Parenteral Nutrition (PN) – Intravenous Feeding

Must-Know: Provided intravenously for patients unable to digest or absorb enteral nutrition (e.g., severe IBD, fistulas, or when GI rest is required).

  • Access: Can be delivered via peripheral or central lines.

  • Complications: Nurses must monitor for occlusion and infection.

  • Nursing Requirements:

    • Placement must be confirmed by X-ray before use.

    • Always use a sterile technique and an infusion pump.

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Nursing School "Must-Know" Safety Summary

  • Standardized Practice: Follow the "right patient, right formula, right tube, right ENFit adapter".

  • Tubing Safety: Trace all lines back to the patient to ensure enteral-to-enteral connections only.

  • No Dyes: Do not add food coloring or dye to enteral feedings.

  • Advancing Diets: Patients in acute care should experience a gradual progression of dietary intake (e.g., clear liquid to full liquid to solid) to manage illness recovery

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Nutritional Needs Across the Lifespan

  • Infants/Children: Focus on breastfeeding, formula, and the gradual introduction of solid foods.

  • Pregnancy/Lactation:

    • Folic acid intake is critical for development.

    • Lactating women require an additional 500 kcal/day above their usual intake.

  • Older Adults:

    • Metabolic rate slows with age.

    • Diminished sensations: Thirst, taste, and smell often decrease, which can lead to poor intake.

    • Barriers: Fixed income, limited transportation, and general health changes.

  • Vegetarian Diets: Nurses must monitor for potential deficiencies in protein and Vitamin B12.

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pressure injuries

  • damage to the skin due to unrelieved pressure

  • found on the bony proviences (butt, heel, elbows, etc)

  • could be found on those with spinsl cord injuries, diabetes, stroke pt (all due to lack of mobilitiy)

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risk factors pressure injuries

  • impaired sensation or mobility

  • alteration in LOC

    • dec awareness and communication skill

  • shear - opposing force (ex: pts gravity is pulling down, bed is pulling up)

  • friction - rubbing force

  • moisture

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ischemia

dec blood supply to an area

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hyperemia (or erythema)

redness

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blanchable

color lightens when pressure applied

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non blanchable

stays red (hyperemia) despite pressure application

  • Non-blanchable erythema is a stage 1 pressure ulcer

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PU Classification

stage 1 - non balchable erthmea of intact skin

stage 2 - partial thickness skin loss w exposed dermis

  • no visble fat (only pink or red)

stage 3 - full thickness skin loss

  • exposed fat (yellow)

  • could see sloth (greenish, yellow discharge or black dead eschar)

stage 4 - pressure injury: full thickness skin and tissue loss

  • to muscle, bone, ligament, tendon

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DTPI (deep tissure pressure injury)

  • granulation tissue - new tissue (pink/red)

  • slough

  • eschar

  • excudate drainage

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wound classifications

  • partial thickness wounds (epidermis, superficial layers)

  • full thickness wounds (epidermis and dermis)

  • primary intention - clean, approx/closed edges, edges of wound line up nicely, lower risk of infection (surgical wound, sutured, etc)

  • secondary intention - edges not approx or line up nicely (ex: road rash, pressure ulcer, wound that got infected)

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complications of wound healing

hemorrhage - bleeding

infection - pain, fever, heat to area, yellow pus (purulent), inc redness, odor

dehiscence - opening/seperation of wound layers (intervention: cover it with wet gauze)

evisceration - opens w something coming out

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drainage terms (serous, purulent, sanguineous, serosanguinous)

serous - clear, watery, thin fluid

purulent - yellow, thick

sanguineous - blood

serosanguinous - watery, pink or red

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prevention injury considerations

  • prediction and prevention (reposition q2h)

  • economic consequences (we don’t get paid and it costs money to treat them)

  • factors influencing pressure injury formation and wound healing

    • nutrition

    • tissue perfusion (DM (high bp slow wound healing, PVD (dec circulation)

    • infection

    • age (dec function macrophages)

    • psychosocial impact of wounds

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differences between ventilation, perfusion, diffusion

ventilation - movement of gasses into and out od lungs (inhale/exhale)

perfusion - cv system pumps oxygenated bloos to tissues and returns deoxygenated blood to lungs

diffusion - process of exchange of repiratoy gasses in avleoli

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alterations in respiratory functining

hypoventilation - RR less than 12

hyperventilation - RR greater than 20

hypoxia - low O2, under 95% room air

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modes of O2 delivery (NEED KNOW: CANNULA VS MASK, FLOW RATES)

nasal cannula (1-6L/min, if greater than 4 then humidify

  • can still eat/talk

  • hook up to sterile water or saline if greater than 4

  • 6L/min MAX for nasal cannula

high flow nasal cannula - provides heated and humidified O2 via NC

oxygen mask (6-12L/min, want greater than 6 to avoid rebreathing exhaled CO2 in the mask)

  • partial rebreather and nonrebreather have reservior bags (10-15L/min)

  • venturi high flow (4-12L/min, usually for COPD)

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Physiology of pain

  • transduction - stimuli

  • transmission - movement, communication

  • perception - awareness: brain intercepts/processes

  • modulation - inhibition of pain impluse

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pain scales: numerical rating scale

  • pt rates pain from 0-10

  • best used for adults/older children who understand numbers

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pain scales: verbal descriptive scale

  • pt chooses words to describe pain such as no pain, mild, moderate, severe, very severe, worst possible pain

  • best for pt who have diffficulty using numbers but can describe pain

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pain scales: visual analog scale

  • pt marks their pain on a straight line, usually from “no pain” to “worst pain”. The nurse measures where they marked

  • pt who can understand visual/spartial concepts

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wong baker faces pain rating

  • pt choose a face that matches their pain lvl, ranging from happy to crying

  • best for children, patients w language barriers, or pt who respond better to pictures

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acute care: pharacological pain therapies

  • patient controlled analgesia

  • topical and transdermal analgesics

  • local anesthesia via injection

  • lock anesthetic infusion

  • epidural

analgesics

  • nonopiods

  • opiods

  • adjuvants

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WHO 3 step ladder

step 1 - mild pain - non opiod

step 2 - moderate pain - weak opiod

step 3 - severe pain - strong opiod

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benner’s stages of nursing proficiency

  • novice - student, new grad

  • advanced beginner

  • competent - 2 to 3 years in setting

  • proficient - greater than 2 to 3 years

  • expert - diverse experience

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professional responsibilities and roles

  • autonomy and accountability

  • care giver - maintain and regain health

  • advocate - advocate for pt safety

  • educator

  • communciator

  • Manager - established environment

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florance nightingale

  • established first nursing philosophy based on health maintenance and restoration

  • organized the first school of nursing

  • First practising epidemiologist

  • reduced mortality rates

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clara barton

  • red cross

  • cared for soilders in the civil war

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