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3 requirements for natural selection
inheritance of traits, variation, and variation in characteristics (reproductive advantage)
A change in the allele frequency of a population as a result of chance events rather than natural selection- important in small populations (bottleneck and founder effect)
genetic drift
tested and confirmed explanation of observations or phenomena
scientific theory
what happens during crossover?
happens during Prophase 1 of meiosis, when homologous chromosomes pair up and exchange genetic material at points called chiasmata. leads to genetic recombination, increasing variation in gametes
Differences between Active transport and Passive transport
passive transport requires no energy and moves substances down their concentration gradient. active transport requires ATP and moves substances against their concentration gradient
DNA structure
double helix built out of nucleotides.
nucleotides have 3 parts, phosphate group, deoxyribose sugar and 4 nitrogenous bases (A, T , C, G).
bases are connected by hydrogen bonds.
antiparallel strands 5'-3' and 3'-5'
DNA located in nucleus of eukaryotic cells
monomers and polymers
carbohydrates-monosaccharides
proteins- amino acids
nucleic acids-nucleotides
lipids-glycerol and fatty acids
Meiosis 1
Homologous chromosomes separate
prophase 1 - pair up and crossing over
metaphase 1- pairs align randomly at metaphase plate
anaphase 1- chromosomes pulled to opposite poles. sister chromatids stay together
telophase 1 and cytokinesis- 2 haploid cells form. each chromosome still has 2 sister chromatids
Meiosis 2
sister chromatids separate
prophase 2- spindles reform in both haploid cells
metaphase 2- chromosomes align at the center
anaphase 2- sister chromatids pulled apart
telophase 2 and cytokinesis- 4 genetically unique haploid daughter cells result and each contains a set of chromosomes
stores DNA and controls cells activities
nucleus
make proteins
ribosomes
synthesizes proteins (covered in ribosomes)
rough endoplasmic reticulum
Synthesizes lipids and detoxifies chemicals
smooth ER
Modifies, sorts, and packages proteins/lipids for transport ("post office")
golgi apparatus
Produces ATP through cellular respiration ("powerhouse")
mitochondria
Perform photosynthesis (convert sunlight to glucose)
chloroplasts (plants only)
Break down waste, damaged organelles, and pathogens ("cleanup crew")
lysosomes
Break down fatty acids and toxins
peroxisomes
Stores water, nutrients, and waste (large in plants)
vacuole
Gives shape, support, and helps with movement (made of microtubules, etc.)
cytoskeleton
controls what enters/exits the cell; maintains homeostasis
cell membrane
Provides structure and protection outside the membrane
cell wall (plants only)
Help organize cell division (part of centrosome)
centrioles ( animal cells)
transcription
process of making an RNA copy of a gene's DNA sequence.
starts with DNA in nucleus and ends with mRNA.
key molecules involved -DNA, RNA polymerase, RNA nucleotides
translation
second step of gene expression, where the mRNA made during transcription is used to build a protein.
starts with mRNA in cytoplasm and ends with protein.
key molecules involved -mRNA, ribosome, tRNA, amino acids
isotope
An atom with the same number of protons and a different number of neutrons from other atoms of the same element.
3 parts of nucleotide
phosphate group, 5 carbon sugar, nitrogenous base
binary fission
how bacteria (prokaryote) divide
1- singular circular DNA chromosome copies itself
2-bacterium gets larger as prepares to divide
3-2 DNA copies move to opposite sides of cell
4-cytokinesis (cell membrane pinches inward, dividing cytoplasm)
5- 2 genetically identical daughter cells result
what is made/ released during photosynthesis?
glucose is made and oxygen is released as a byproduct.
ATP ( temporary energy source) and NADPH (provides electrons for glucose production) are intermediate molecules
codon
found in mRNA and specifies the amino acid
anticodon
found on tRNA and matches codon + delivers right amino acid during translation
codons and anticodons interaction
1-Ribosome reads the mRNA codon
2-A tRNA with the complementary anticodon binds to the codon
3-The tRNA carries the correct amino acid
4-The amino acid is added to the growing polypeptide chain
endosymbiosis theory
proposes that mitochondria and chloroplasts originated as free-living prokaryotes that were engulfed by a host cell and evolved into organelles.
peppered moth story
Before Industrial Revolution:
-Light-colored moths blended into clean, lichen-covered trees
-Dark moths were rare (eaten more often)
After Industrial Revolution:
-Trees darkened from soot
-Dark moths were camouflaged
-Light moths were eaten more
Result:
-Dark moths became more common
-Shows natural selection based on environmental change
rubisco
Most important enzyme in photosynthesis.
Catalyzes carbon fixation in the Calvin cycle (adds CO₂ to RuBP).
Found in chloroplasts.
ATP synthase
Makes ATP during the light-dependent reactions
Uses energy from the proton gradient (chemiosmosis)
NADP⁺ Reductase
Final step in light reactions
Transfers electrons to NADP⁺ → forms NADPH (used in Calvin cycle)
the process of converting inorganic CO₂ into organic molecules (like sugars) during photosynthesis. occurs in Calvin Cycle + catalyzed by rubisco
carbon fixation
eukaryote
nucleus, DNA is linear, has membrane bound organelles
ex: plants, fungi, animals, protists
prokaryote
no nucleus, DNA is circular in cytoplasm, no membrane bound organelles, smaller size
ex: bacteria, archaea
directional selection
Definition: Favors one extreme trait
Bell curve: Shifts left or right
Example: Dark-colored moths become more common after pollution
stabilizing selection
Definition: Favors the average trait, not extremes
Bell curve: Narrows around the middle
Example: Human birth weight — too low or too high is risky
disruptive selection
Definition: Favors both extremes, not the average
Bell curve: Splits into two peaks
Example: Birds with small or large beaks survive better than medium
increases H+ concentration
ph< 7
acid
increases OH- concentration
ph>7
base
how atomic mass is determined
The weight of an atom is called its atomic mass (or atomic weight), and it is determined by: Protons and Neutrons
Electrons are so small they barely contribute to mass
atomic number
number of protons in nucleus of atom
A pair of chromosomes — one from each parent — that are similar in size, shape, and gene content.
They carry the same genes, but possibly different versions (alleles).
homologous chromosome
Body parts in different species that have a similar structure and shared evolutionary origin, even if their functions differ.
homologous structures
It stores and transports energy for nearly all cellular processes
Energy is released when one of its phosphate bonds is broken (→ becomes ADP)
ATP (adenosine triphosphate)
1 division, 2 cells produced, no chromosome number change, makes body cells (somatic)
purpose: growth, repair, and asexual reproduction
mitosis
2 divisions, 4 cells produced, chromosome number changed by half, makes sex cells (gametes)
purpose: produce gametes (sperm or egg) for sexual reproduction
how does a enzyme catalyst affect a reaction?
lowers activation energy by reducing the amount of energy needed to start the reaction, so reaction is faster and more efficient.
increases reaction rate by lowering activation energy enzymes allow more reactions to occur in less time, so rxn completion is faster than it would be without the enzyme catalyst.
Forms of active transport (require energy), Types of endocytosis, Involve the cell membrane folding in to form vesicles. cell eating, large particles taken in, large vesicle, common white blood cells, and purpose is to defense, remove invaders and eat solids
phagocytosis
Forms of active transport (require energy), Types of endocytosis, Involve the cell membrane folding in to form vesicles. cell drinking, fluids + small dissolved molecules take in, small vesicle, most cells are common, and the purpose is to absorb nutrients, sample surroundings
pinocytosis
Parts of the Cell Cycle
Interphase (G1, S, and G2), Mitosis, Cytokinesis
triglyceride structure + function
glycerol + 3 fatty acids
energy storage
phospholipid structure + function
glycerol + 2 fatty acids + phosphate group
forms cell membranes
light-dependent reactions + where
part of photosynthesis that absorbs energy from sunlight and transfers energy into chemical energy.
happens in thylakoid membrane of a chlorplast (plant cell)
light independent reactions
set of reactions in photosynthesis that do not require light; energy from ATP and NADPH is used to fix CO2 into glucose.
happens in stroma of chloroplast (fluid-filled space outside thylakoid)
where is most ATP made?
cellular respiration- electron transport chain in inner mitochondrial membrane
Enzymes Truth
nondisjunction
Error in meiosis in which homologous chromosomes fail to separate. leads to aneuploidy
aneuploidy
Abnormal number of chromosomes.
homozygous
An organism that has two identical alleles for a trait
heterozygous
An organism that has two different alleles for a trait
hemizygous
only one copy of a gene
dominant
allele that masks the other; expressed if present
recessive
only expressed if both alleles are recessive
genotype
genetic makeup of an individual
phenotype
the physical trait expressed
allele
a version of a gene
nature of the cell membrane
Has a hydrophobic head (phosphoric acid-glycerol) and hydrophilic tail (two fatty acid chains-one kinked).
"fluid mosiac model"
the central dogma
genetic information flows in living organisms:
DNA stores it
RNA carries it
Proteins express it
exergonic
Releases energy (e.g., cellular respiration)
Products have less free energy than reactants
negative ΔG
endergonic
Requires energy input (e.g., photosynthesis)
Products have more free energy than reactants
positive ΔG
activation energy
the minimum amount of energy required to start a chemical reaction
free energy
energy that is available to do work
reactants
elements or compounds that enter into a chemical reaction
products
The elements or compounds produced by a chemical reaction.
anabolism
builds molecules
catabolism
breaks molecules down
cell to cell junctions
tight junction, desmosomes, gap junctions, and plasmodesmata
stages of mitosis
prophase, prometaphase, metaphase, anaphase, telophase
prophase
Chromosomes become visable, nuclear envelop dissolves, spindle forms
Prometaphase (Mitosis)
The nuclear membrane disintegrates. Spindle microtubules attach to chromatids.
metaphase
Chromosomes line up in the middle of the cell
anaphase
sister chromatids are pulled apart
telophase
2 nuclei form, chromosomes decondense
cytokinesis
division of the cytoplasm to form two separate daughter cells
major polysaccharides
starch, glycogen, cellulose, and chitin
starch
long chains of glucose branched and unbranched in plant cells their function is energy storage in plants
glycogen
Highly branched chains of α-glucose in animal cells
their function is short term energy storage in animals
cellulose
Straight, rigid chains of β-glucose in plant cells.
its function is structural support in plant cell walls
chitin
Chains of β-glucose + nitrogen-containing side groups in fungi and arthropods
its function is structural- forms of exoskeletons and fungal cell walls
hierarchy of organization for living cells
atom, molecule, organelle, cell, tissue, organ, organ system, organism, population, community, ecosystem, biosphere
hydrophobic
"Water-fearing" — does not dissolve in water
hydrophillic
"Water-loving" — dissolves easily in water
sodium potassium pump
a carrier protein that uses/requires ATP to actively transport 3 sodium ions out of a cell and 2 potassium ions into the cell.
Maintains electrochemical gradient
Found in animal cells, crucial for nerve and muscle function
photosynthesis
in chloroplasts (plants). converts light to glucose