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in negative sense RNA
RNA-dependent RNA polymerase is used to synthesize mRNA transcripts from the viral genome.
What does a subunit vaccine contain?
Specific antigens (proteins) from a pathogen (NOT the whole pathogen)
What is the purpose of a vaccine?
To expose the body to antigens → trigger immune response → create memory
Which cells produce antibodies?
Plasma cells (activated B cells)
Which response most likely occurs in an individual to whom a subunit vaccine has been administered?
Production of antibodies by plasma cells
What is a negative-sense RNA virus?
RNA must be converted to positive-sense RNA before translation
Vaccine →
Antigen → Plasma cells → Antibodies
the site that is cut to introduce the gene to be cloned.
polylinker site
The center of the lumen will contain the
spermatozoan - the most advanced stage
The cells located adjacent to the basement membrane outside of the seminiferous tubule are the
leydig cells
The cells located adjacent to the basement membrane within the seminiferous tubule are
spermatogonia or the Sertoli cells.
what is located within the seminiferous tubules between the basement membrane and the center of the lumen
spermatocytes
Which mature cells always lack Barr bodies?
erythrocytes
Why can peptide hormones NOT cross membranes?
They are polar/water-soluble and are repelled by the hydrophobic membrane interior
Steroid hormone receptor location
Intracellular (cytoplasm or nucleus)
Peptide hormone receptor location
Cell membrane
Steroid hormones usually act as what?
Transcription factors regulating gene expression
Peptide hormones usually use what signaling system?
Second messengers (often cAMP)
Which hormone diffuses through the cell membrane of its target cells to reach its receptor?
aldosterone
Exons =
translated
Introns =
removed before translation
Euchromatin vs heterochromatin
Euchromatin = open, transcriptionally active
Heterochromatin = closed, transcriptionally inactive
Why does histone acetylation open chromatin?
Acetylation neutralizes positive histone charges, weakening histone-DNA interactions
Which chromatin type allows transcription factor access?
eurochromatin
Which chromatin type blocks transcription factors?
heterochromatin
Which process would be the first affected if dividing eukaryotic cells were treated with an inhibitor of spindle fiber elongation?
aster formation
Which cells are the precursors of the cellular fragments that are part of a clot?
megakaryocytes
the largest type of leukocytes in blood and can differentiate into macrophages and monocyte-derived dendritic cells.
monocytes
granulocyte precursors, developing from myeloblasts and developing into myelocytes
progranulocytes
the hypothalamus is a brain structure that originates from the
ectoderm
the trophoderm gives rise to the
placenta
what is required for mitosis to initiate
cyclin + Cdk1
The association of cyclin with Cdk1 controls
entry into mitosis
Since Type I Bartter syndrome is autosomal recessive, an individual needs to possess
two copies of that gene (be homozygous - aa)
The ascending loop of Henle is positioned directly adjacent to the
distal convolated tubule
if there is increased urinary output, that is indicative of
decreased water reabsorption and higher blood pressure
if you see: cAMP / GPCR / membrane receptor, think
Protein hormone made in rough ER
Ribosomes can be:
Free →
Bound (rough ER) →
cytosol proteins, secreted proteins
what do viral loads exhibit
a sharp increase which is followed by a decrease
Glycosides are formed when a carbohydrate covalently binds via its anomeric carbon to another molecule through a hydroxyl. This forms a glycosidic bond, which is functionally classified as an
acetal
bond formed between a carboxylic acid and alcohol.
ester
This is a type of bond formed between two acids.
anhydride
bond that forms between an amine and carboxylic acid
amide
what is the first intermediate of the pentose phosphate pathway
glucose 6-phosphate dehydrogenase
All steroids contain
four hydrocarbon rings and a hydroxyl group
cholesterol is a
steroid
location where action potentials are generated
axon hillock
generates a postsynaptic potential in direct response to neurotransmitters?
dendrites
the location where neurotransmitters are released.
axon terminal
segments along an axon that propagate an action potential
nodes of ranvier
After fertilization, the
corpus luteum is maintained for progesterone production.
Immediately after the sperm enters the oocyte,
meiosis II
meiosis I is completed
prior to ovulation
corpus luteum transforms into ____ in the event that fertilization does not occur.
corpus albicans
required for the maintenance of pregnancy
progesterone secretion
Glioblastomas arise from glial cells, which include
astrocytes
Fibroblasts form
connective tissue
synthesis of insulin and glucagon happens in the
pancreatic islets
transport of digestive enzymes happens in the
pancreatic duct