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Medication standards of safety
Legislation and pharmacological concepts
Legislation
FDA regulations, state and local regulations, health care organizations/institutions, professional organizations
FDA regulations
All medications on the market undergo vigorous testing for safety
State and local regulations
Additional controls, including alcohol and tobacco
Healthcare organizations/institutions
Policies and procedures on medication administration
Professional organizations
Defining the scope of practice for nurses
Pharmacological concepts
Medication names, classification, forms, medication actions
Medication names
Chemical vs. generic vs. proprietary
Medication classification
Effect on body system, symptoms it relieves, desired effect
Medication route in body
Absorption, distribution, metabolism, excretion
Medication forms
Solid, liquid, powder, ointment, cream, paste, powder, patch, gum, suppository, parenteral
Medication actions
Therapeutic effect, adverse effect, side effect, toxic effect, idiosyncratic effect, allergic reactions, interactions, tolerance, dependence
Therapeutic effect
Expected or predicted physiological effect
Adverse effect
Undesired, unpredicted & unpredictable responses
Side effects
Predictable and unavoidable effects
Toxic effects
Impaired metabolism or excretion
Idiosyncratic effects
Under/overreaction
Allergic reactions
Unpredictable immune response
Medication interactions
When one medication modifies the action of another (antidote vs. synergistic effect)
Medication tolerance
Body's decreased response to a medication after prolonged use
Medication dependence
When a person experiences withdrawal symptoms when a medication is stopped abruptly
Routes of drug administration
Enteral, topical, inhalations, parenteral, other routes
Enteral routes
Oral, sublingual, buccal, NG tube, orogastric tube, gastrostomy tube, jejunostomy tube, rectal
Topical routes
Skin preps, transdermal patches, mucous membranes
Inhalation routes
Aerosol therapy, metered dose inhalers
Parenteral
Intradermal, subcutaneous, intramuscular, intravenous
Other routes
Intrathecal, epidural, intraperitoneal, intrapleural, intraosseous
Prescribers
NPs, physicians, physician’s assistants, nurses do not prescribe
Orders
Written (hand or electronic), verbal, telephone
Types of HCP orders
Standing/routine, PRN, single, now, STAT, prescriptions
Standing/routine orders
Administered until dosage is changed or another med is prescribed
PRN orders
Given when patient requires it
Single (one-time) orders
Given one time only for a specific reason
STAT orders
Given immediately in an emergency
Now orders
When a medication is needed right away, but not STAT
Prescription orders
Medications to be taken outside of the hospital
Seven rights of medication
Right medication, dose, patient, route, time, documentation, reason
Right documentation (5 W’s)
When, why, what, where, was
Safety for all meds
Two patient identifiers, check allergies and 7 rights, avoid distractions, use clinical judgement, right assessment, right evaluation
Nursing diagnoses
Impaired health maintenance, knowledge deficit related to medication, non adherence to medication regimen, adverse reaction or adverse interaction, complex medication regimen (Polypharmacy)
Oral, sublingual, and buccal route
Easiest and most desirable route, taken with fluid, food sometimes affects absorption
Buccal medication administration
Placed between the cheek and the gum
Sublingual medication administration
Placed under the tongue
Topical medication application
Use gloves and applicators, clean skin first, use sterile technique if the patient has an open wound, apply evenly, cover as ordered
Transdermal patch medication administration
Remove old patch before applying new, wash skin, document location of new patch, apply a label to patch if it is difficult to see, write date/time of placement, document removal of patch
Types of topical medications
Creams, ointments, pastes, lotions, transdermal patches
Small-bore feed medication administration
Verify tube location is compatible with medication absorption, use elixirs/liquid when possible, crush/dissolve other tablets, DO NOT open extended release capsules, 30ml water flush before and after, prepare each med in separate cup, if medication is to be given on empty stomach, allow 30 minutes before or after feeding, risk of drug-drug interactions is higher
Types of inhalation medication administration
Metered dose inhalers, dry powder inhalers
Ophthalmic medication administration
Wash hands/wear gloves, let drops warm up to room temperature, position patient semi fowlers or supine, clean eyelid margins as needed, roll bottle between palms, do not lay cap down, drop into conjunctival sac
Ear medication instillation
Instill at room temperature, use sterile solutions, check for eardrum rupture if patient has ear drainage, never occlude ear canal with dropper or syringe, instill 1cm above ear canal, apply gentle massage to tragus, remain side lying for 2 min, document drainage or pain
Rectal instillation medication instillation
Place on anal-rectal ridge so body can absorb
Preparing an injection from an ampule
Snap off ampule “neck” with an alcohol pad, aspirate medication into syringe using filter needle, replace filter needle with appropriate size needle, administer injection
Preparing an injection from a vial (closed system)
If dry, reconstitute with solvent or diluent as needed, calculate correct volume to withdraw, remove cap, pull back plunger to fill with air (same as medication amount), push needle tip into cap, inject air into vial, invert vial and allow air pressure to fill syringe gradually, tap barrel to get rid of bubbles once needed amount is reached (eject remaining air into vial if needed), cover needle with safety sheath or cap
Intradermal route
Medicine introduced in the dermis, 10-15 degree angle, <0.5 ml, forms a bleb or wheal, used for TB or allergy testing
Subcutaneous route
Medicine administered to the fat, 45-90 degree angle, 1 ml max, give slowly
Intramuscular injection sites
Deltoid, ventrogluteal, vastus lateralis, dorsogluteal
Z-track method
Prevents medication from tracking back along needle path
Intramuscular injections
Identify appropriate landmarks, cleanse area with alcohol swab, make skin taunt with nondominant hand, inject at appropriate angle with dominant hand, aspirate (not for immunizations), continue with injection, remove needle, activate needle safety, apply bandage, document
Medication safety
Keep narcotics locked in place, return cloudy liquids to pharmacy, nurse who prepares med administers it, do not leave medication at the bedside, prepare medications for one patient at a time, do not label meds by patient room or bed number
Sharps safety
Never recap used needles, dispose of sharps in marked containers, use puncture- and leak-proof containers, never force needles into receptacle or place used needles into wastebaskets, pockets, or patient’s tray or bedside
Medication errors
Report all errors, patient safety is top priority, documentation required, nurse is responsible for preparing a written occurrence or incident report (accurate, factual description of what occurred and what was done)
Nurse’s role in medication administration
Determining if medications ordered are correct, assessing patient’s ability to self-administer, determining if patient should receive medications at a given time, administering medications correctly, closely monitoring effects and side effects, communication with healthcare team/advocacy, cannot be delegated, includes patient/family teaching