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Regulatory genes
produce proteins that bind to operator
Promoter
BRE,TATA, BRE, Inr, MTE, DPE
Operator
genetic switch
Structural genes
DNA segment that codes for protein
Inducible
Usually off
Repressible
Usually on
Oc
Constitutive expression
Is
repressor stays on operator forever
I-
repressor cannot bind to operator
Z-
Always no
DNMT
no gene expression
Unmethylated DNA
Gene expression
HATS
Gene expression
HDAC
no gene expression
TBP binds to
TATA box
TFIIB binds to
BRE
RNA pol II binds to
Inr
processes that provide steady state level of RNA
Rate of transcription and mRNA degradation rates
mRNA stability mechanisms
deadenylation, decapping, and endoribonuclease
Causes of cancer
Mutations and abnormally expressed genes