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Biological Bases of Behavior
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neurons
a nerve cell - the fundamental unit of the brain and nervous system
multiple sclerosis
a chronic, often disabling disease that impacts the brain (when the immune system mistakenly attacks the myelin sheath)
neural transmission
the process by which neurons communicate with other parts of the body through a chemical message called neurotransmitters
resting potential
the, stable, negatively charged state of a neuron when it is inactive (-70 mV)… the cell is ready but not firing yet
threshold
the amount of stimulus required to trigger a neural impulse
depolarization
the process during the action potential when the cell’s charge turns from negative to positive (since positive ions flood the membrane)
action potential
a brief electrical charge that travels down the axon of a neuron (the actual firing part of the process)
excitatory
a signal that makes the neuron more likely to fire an action potential
inhibitory
a signal that makes the neuron less likely to fire an action potential
dopamine
a neurotransmitter involved in the reward process, motivation, motor control, and executive function
a low or high amount of dopamine is associated with…
schizophrenia and/or Parkinson’s disease
glutamate
a type of neurotransmitter that is the primary exciter of neurons (excitatory), too much can create overstimulation in the brain, leading to seizures and headaches
GABA
a type of neurotransmitter that is the primary inhibitor of neurons (inhibitory), too much can lead to fatigue while too little can lead to tremors, insomnia, seizures, etc (after all it does help you relax)
endorphines
a neurotransmitter that controls pain and is linked to reward (think “morphine” when you see the word), creates runner’s high
substance P
a neurotransmitter involved in transmitting pain messages to the brain
acetylcholine (ACh)
involved in memory and learning (the two go hand in hand), and very randomly, muscle movement
what two diseases are linked to a problem with acetylcholine
1) Alzheimer’s: Linked to the deterioration of neurons that produce ACh
2) Myasthenia Gravis: A disease of severe muscle weakness linked to antibodies that BLOCK ACh receptor sites in the brain
sensory neurons (afferent)
neurons that transmit messages from the body to the brain and spinal cord
motor neurons (efferent)
carry messages from the brain to the body (make you move after thinking)
interneurons
neurons in the brain and spinal cord that communicate with other neurons in the brain and spinal cord (thus the word inter)
reflex arcs
a simple, automatic response to a sensory stimulus that skips sending a message to the brain and is processed in the spinal cord for speed (think knee jerk)
central nervous system
brain + spinal cord
peripheral nervous system
everything besides the brain + spinal cord
somatic
controls voluntary movements of skeletal muscles
autonomic
controls life-essential, unconscious actions like heart rate and breathing
what two systems are within the autonomic part of the nervous system
sympathetic and parasympathetic
sympathetic nervous system
arouses the body and mobilizes energy in stressful situations (fight or flight)
parasympathetic
calms the body down, conserves energy (rest and repair)
endocrine system
system of hormones that cause different responses in the body
epinephrine
a hormone that increases heart rate, blood pressure, etc (adrenaline)
leptin
a hormone secreted by fat cells that tell you you’re full
ghrelin
secreted by an empty stomach, tells the brain you’re hungry (grrr in ghrelin = equal growling stomach)
melatonin
a hormone secreted by the pineal gland that regulates the sleep cycle
oxytocin
the cuddle hormone that helps humans bond
lesioning
the destruction of part of the brain
electroencephalogram
helps scientists examine the brain by looking at electrical brain waves, good for sleep studies
functional MRI (fMRI)
shows areas of the brain AND brain activity, it does so by looking at blood flow
medulla
part of the hindbrain and located at the base of the brainstem, controls heartbeat and breathing
cerebellum
part of the hindbrain, controls sensory input and coordinates movement + balance, looks like a little brain
pons
part of the hindbrain, focuses on facial recognition
reticular formation
a nerve network that travels through the brainstem and the thalamus
thalamus
part of the forebrain, the brain’s sensory control center - directs messages to the sensory receiving areas of the cortex so you can see, touch, hear, etc (doesn’t control smell though)
hypothalamus
directs several life maintenance functions (eating, drinking, body temperature), and has the pituitary gland (the master gland that controls the endocrine system)
amygdala
two lima bean sized neural clusters in the forebrain (specifically the limbic system), governs emotion (particularly anger and fear)
hippocampus
a processing center for long term (explicit memories), but is NOT where long-term memories are ultimately stored, think of it like a librarian
brainstem
focused on the survival of the person and life-sustaining functions (includes medulla, pons, and midbrain), slightly different from the hindbrain because the hindbrain is separate from the midbrain, and also includes the cerebellum
limbic system
a donut shaped system associated with drive and emotions (contains the hypothalamus, amygdala, and hippocampus)
hemispheric organization
the brain is split into two hemispheres that have different purposes and parts
brain lateralization
the idea that the brain’s two hemispheres have different specialties
contralateral control/organization
lateralization "contradicts” or “crosses” over—in other words, one side of the brain controls the opposite side of the body
corpus callosum
the bridge that connects the two hemispheres (basically a large band of neurons that carries messages between the two sides)
split brain patients
patients who exhibit and prove brain lateralization because their corpus callosum has been severed (so the two sides of their brain can no longer communicate)
cerebral cortex
the outer skin of the brain that is divided into four lobes
temporal lobe (the “ears”)
linguistic processing (the brain’s ability to process language)
Wernicke’s Area: located in the left temporal lobe, involved in language comprehension
wernicke’s aphasia
when Wernicke’s Area is damaged, people speak fluent words that make no sense (word salad) and can’t comprehend the words of others
occipital lobes (the “eyes”)
located at the back of the head, includes areas that receive and process visual information
the parietal lobes (the “navigator”)
located on top of the temporal lobe near the rear of the brain
Includes:
somatosensory cortex: area that registers and processes body touch and movement sensations
phantom limb syndrome
a condition where someone experiences pain or sensations in a limb that is no longer there (usually caused by mistakenly interpreted neural impulses by the somatosensory cortex)
frontal lobes (the “Executive”)
the front of the cerebral cortex that participates in conducting planning, muscle movements, and speech
prefrontal cortex
located in the very front of the frontal lobe, is the executive function of the brain and manages things like decision making, planning, impulse control, and personality
motor cortex
located at the rear of the frontal lobe, an area that controls voluntary movements
Broca’s Area
located in the frontal lobe and directs the muscle movements required to create coherent speech
Broca’s Aphasia
damage to the Broca’s Area that allows you to understand words but not be able to speak them
association areas
areas in the cerebral cortex not associated with primary motor or sensory understanding but rather higher mental functions like thinking, remembering, and speaking
priming
an implicit memory effect where seeing one stimulus influences you to respond more efficiently to another (for example, seeing the color yellow might make it faster for you to recognize the word banana)
consciousness
our subjective awareness of ourselves, others, and our environment
includes various states such as alertness, sleep, and altered states influenced by drugs and hypnosis
blindsight
a neurological condition where people with visual impairment can respond to stimuli in their “blind field”, despite not actively seeing that stimuli
reuptake
the process by which neurotransmitters are reabsorbed by their sending neuron
this recycles the chemicals and regulates signals
agonists
Direct: resemble neurotransmitters and bind to receptor sites in their place
Indirect: block the reuptake of neurotransmitters, skyrocketing their levels and increasing their effects
antagonists
molecules/chemicals that completely block the receptor sites of the dendrite, making it so neurotransmitters aren’t effective
psychoactive drugs
chemical substances that alter your psyche - your emotions, moods, perceptions, or consciousness by acting on your nervous system
tolerance
the diminishing of the effect of a drug taken in the same doses, requiring the user to take larger and larger amounts
withdrawal
the discomfort/distress that follows discontinuing a drug or behavior
what are the four major drug classifications
depressants, stimulants, opiates, hallucinogens
depressant
a drug that reduces neural activity and slows body functions
what is the classification of alcohol
depressant - lowers inhibitions, slows neural processing, and disrupts memory formation by repressing REM sleep
stimulants
drugs that excite neural activity and speed up body functions
the world’s most widely consumed psychoactive substance
caffeine
what classification is caffeine
stimulant - it increases alertness by blocking a neurotransmitter that makes you sleepy (adenosine)
what classification is cocaine
stimulant - powerful stimulant that blocks the reuptake of dopamine, norepinephrine and serotonin, spiking levels of alertness and euphoria
hallucinogens
drugs that evoke sensory images and distort perceptions in the absence of sensory input (hallucinations)
LSD
a powerful synthetic drug that causes a “trip” and evokes a sense of euphoria or panic
closely resembles a prototype of serotonin
what is the classification of marijuana
hallucinogen - marijuana is often classified as a mild one, it amplifies sensitivity to colors, sounds, and tastes
however it also has some depressant-like effects (like relaxation)
what is the classification of ecstasy
considered both a stimulant and mild hallucinogen - major impact is causing the release of serotonin and blocking its reuptake
opiates (narcotics)
mimic the body’s painkillers and suppress neural activity
what is the mechanism of opiates
agonists: they flood the brain and mimic endorphins, causing the brain to stop producing natural ones, which leads to agonizing withdrawal
what classification is heroin
opiate
circadian rhythm
the biological clock - regulates bodily rhythms like temperature and wakefulness on a 24-hour schedule
sleep onset
the period when we are falling asleep (in between wakefulness and sleep), periods of being drowsy while awake
alpha waves
the waves our brains produce when we are drowsy yet awake
NREM 1
the transition from wakefulness to sleep, characterized by theta waves (high frequency, low amplitude waves)
NREM 2
the stage of sleep where you spend the most time
characterized by theta waves and sleep spindles (short bursts of rapid brain waves)
NREM 3
deep sleep or slow wave sleep, characterized by slow, large “delta” waves
this stage of sleep is difficult to wake from and is when the body repairs itself
NREM 4
also a stage of deep sleep characterized by delta waves (slow waves = slow, low frequency)
what is a way to encourage an increase in NREM 3 and 4
exercise
what happens after NREM stage 3 and 4?
we start to reverse and go through stages NREM 2 and 1
REM sleep (paradoxical sleep)
the stage of sleep characterized by a paralyzed body (though sometimes with slightly twitching muscles) and rapid eye movement, also the stage where dreams are most likely to occur
known as paradoxical sleep because our brain waves appear as active and intense as when we are awake
REM rebound
what you experience after being deprived or REM sleep, longer periods of REM sleep than normal the next day after being deprived
how long does a stage of sleep last
90 to 120 minutes
insomnia
a sleep disorder that creates persistent problems of getting to sleep or staying asleep