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Last updated 1:02 PM on 5/19/26
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Gray 2011

mtHTT inhibit histone modification enzymes e.g histone deacetylases leading to dysregulation of transcription

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Cleveland 2012

ASO for huntingtons disease via spinal infusion in rodent models shown to reduce HTT levels

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Halliday 2025

Diagnosis of Parkinson’s disease through symptomatic progression

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Li-Hau 2023

DJ-1 mutation impair respiration in mouse models shown to

Neuroinflammation damage in post mortem tissue

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Vitorica 2021

impaired phagocytosis of amyloid beta plaques and dystrophic neurons by astrocytes in Alzheimer’s