Lecture 19: Basic Principles of Stem Cell and Cellular Therapies
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22 Terms
G0 phase
In differentiation, the cell exits the cell cycle and remains in what phase?
proliferate
process of dividing cells in two
differentiation
process where a cell becomes specialized
hemophilia
inability of liver cells to produce clotting factors
embryonic stem cells, adult stem cells, fetal stem cells, umbilical cord stem cells
types of stem cells in developmental stage
somatic cell nuclear stem cells, induced pluripotent stem cells, parthenogenetic stem cells
types of stem cells derived in a laboratory
pluripotent
potency of embryonic stem cells (ES cells)
multipotent or unipotent
potency of adult stem cells
multipotent
potency of fetal stem cells
multipotent
potency of umbilical cord stem cells
pluripotent
potency of somatic cell nuclear (SCNT) stem cells
pluripotent
potency of induced pluripotent stem cells (iPS cells)
pluripotent
potency of parthenogenetic stem cells
pluripotent
can give rise to all cells in body
multipotent
can give rise to multiple cell types in body
unipotent
can give rise to one cell type
totipotent
can give rise to all cell types in body (including extraembryonic tissue)
multipotent
potency of most adult stem cells
gastrula
comes from cells in inner cell mass (ICM) of blastocyst
endoderm
forms soft tissues (liver,pancreas)
mesoderm
muscle, blood, bone
ectoderm
forms skin, nerve cells