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Inhibition of cell wall synthesis (BCPV)
Penicillins
Cephalosporins
Bacitracin
Vancomycin
Inhibition of protein synthesis (CETS)
Chloramphenicol
Erythromycin
Tetracyclines
Streptomycin
Inhibition of nucleic acid replication and transcription (1)
Rifampin
Injury to plasma membrane (1)
Polymyxin B
Inhibition of essential metabolite synthesis (1)
Sulfanilamide
Mechanisms of Bacterial Drug Resistance (5)
Blocking drug entry into the cell
Inactivation of the drug by enzymes
Alteration of the drug’s target site
Efflux/ejection of the drug from the cell
Alteration of the metabolic pathways of the host
Occurs naturally through mutations