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Diethylsilbisterol (DES)
Anti-abortion
DES pathogenesis
Abnormal Mullerian Tract differentiation
DES in mom and daughter
Daughter- increases risk for vaginal and/or cervical cancer (glial cell adenocarcinoma)
Mom- Increased risk for breast carcinoma
Vinyl Chloride (PVC)
causes Hepatic angiosarcoma
Asbestos
Causes Malignant Mesothelioma
Nitrites
Causes Gastric carcinoma (Asia)
Alfatoxin B1
causes Hepatocellular carcinoma
Naturally occurring in Aspergillus