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Gas Exchange
→ Movement of O₂ into blood and CO₂ out of blood at the alveoli
Normal SpO₂
→ 95-100%
Normal PaO₂
→ 80-100 mmHg
Diffusion
→ Movement of gases from high to low concentration
Hypoxia
→ Low oxygen in tissues
Signs of Hypoxia
→ Dyspnea, restlessness, confusion, cyanosis (late), tachycardia
Hypercapnia
→ Excess CO₂ in bloodstream
Signs of Hypercapnia
→ Headache, drowsiness, confusion
COPD
→ Chronic obstructive disease causing airflow limitation
Common Causes of Impaired Gas Exchange
→ COPD, asthma, pneumonia, PE, atelectasis, pneumothorax
Incentive Spirometer Purpose
→ Prevent atelectasis & improve lung expansion
Asthma Rescue Medication
→ Short-acting bronchodilator (albuterol)
Status Asthmaticus
→ Severe asthma attack not relieved by meds (emergency)
Pulmonary Fibrosis
→ Stiff lungs causing decreased oxygenation (restrictive)
Cystic Fibrosis
→ Genetic disease causing thick mucus in lungs
CF Diagnostic Test
→ Sweat chloride test
Ventilation
→ Movement of air in/out of lungs
Perfusion
→ Blood flow to lungs
Diffusion (V/Q relationship)
→ Gas exchange between alveoli & capillaries
Respiratory Acidosis Cause
→ Hypoventilation → CO₂ retention
Restrictive Lung Disease
→ Decreased lung expansion
Obstructive Lung Disease
→ Difficulty exhaling air
Fluid Balance
→ Balance between intake and output
Normal Sodium
→ 135-145 mEq/L
Normal Potassium
→ 3.5-5.3 mEq/L
Normal Calcium
→ 8.2-10.2 mg/dL
Normal Magnesium
→ 1.6-2.2 mg/dL
Isotonic Solution
→ Same concentration as blood (0.9% NS)
Hypotonic Solution
→ Moves fluid INTO cells
Hypertonic Solution
→ Moves fluid OUT of cells
Fluid Volume Deficit Causes
→ Vomiting, diarrhea, burns, hemorrhage
Fluid Volume Excess Causes
→ CHF, kidney failure, excess IV fluids
Hypokalemia
→ Low potassium
Hypokalemia Symptoms
→ Weakness, arrhythmias, ↓ GI motility
Hyperkalemia
→ High potassium
Hyperkalemia Symptoms
→ Arrhythmias, muscle weakness, peaked T waves
Dehydration Signs
→ Dry skin, low BP, tachycardia
Fluid Overload Signs
→ Edema, high BP, bounding pulse
Albumin Function
→ Maintains oncotic pressure, keeps fluid in vessels
Daily Weight Importance
→ Best indicator of fluid status
Diuretics Effect
→ Increase fluid loss and potassium loss
Hypertonic IV Risks
→ Pulmonary edema, fluid overload
Normal pH
→ 7.35-7.45
Acidosis
→ pH < 7.35
Alkalosis
→ pH > 7.45
Respiratory Acidosis
→ CO₂ retention (hypoventilation)
Respiratory Alkalosis
→ CO₂ loss (hyperventilation)
Metabolic Acidosis
→ Low HCO₃ (ex: DKA, diarrhea)
Metabolic Alkalosis
→ High HCO₃ (ex: vomiting)
Compensation
→ Body correcting pH imbalance
Lungs Role
→ Control CO₂ (fast compensation)
Kidneys Role
→ Control HCO₃ (slow compensation)
Kussmaul Respirations
→ Deep, rapid breathing to remove CO₂ (DKA)
ABG Interpretation Step 1
→ Check pH
ABG Interpretation Step 2
→ Check CO₂
ABG Interpretation Step 3
→ Check HCO₃
ABG Interpretation Step 4
→ Determine compensation
pH & CO₂ Relationship
→ Opposite directions
pH & HCO₃ Relationship
→ Same direction
Vomiting Effect on pH
→ Causes metabolic alkalosis
Hypoventilation Effect
→ Causes respiratory acidosis
Priority for Low SpO₂
→ Administer oxygen first
High-Risk Respiratory Patient
→ Elderly with chronic lung disease
Hyponatremia Intervention
→ Restrict water
Hypokalemia Priority
→ Risk for cardiac arrhythmias
DKA ABG Result
→ Metabolic acidosis
Prolonged Vomiting Result
→ Metabolic alkalosis
COPD patient is drowsy with SpO₂ 88%. What’s happening?
CO₂ retention → respiratory acidosis
First action for pneumonia pt w/ PaO2 60 mmhg?
Admin O2 due to impaired gas exchange
Tonsillectomy pt swallowing repeatedly- priority?
Suspect hemorrhage because frequent swallowing means bleeding
Asthma attack along with silent chest means?
Status asthamticus→ airway closing
CF child w/ thick mucus, what is the best intervention ?
Nebulized hypertonic saline or mucolytic
COPD pt on high O2 become confused, why?
Hypoventilation → CO2 retention/narcosis
Child w/ RSV is retracting and fatigued, what is priority?
Suction airway due to secretions causing obstruction
Post‑bronchoscopy patient wants water — what must you check first?
Gag reflex
Patient with pleural effusion has absent breath sounds — next step?
Prepare for thoracentesis (removes fluid)
DKA patient breathing deep and rapid — what is this?
Kussmaul respirations
Child with TEF is coughing, choking, cyanotic — priority?
Stop feeds + suction
Patient with pulmonary fibrosis — what type of disorder?
Restrictive
Pneumothorax patient suddenly has tracheal deviation — priority?
Prepare for needle decompression
Child with bronchiolitis has nasal flaring + retractions — what’s failing?
Airway patency
Patient with pleural effusion has dyspnea + dull percussion. What’s the intervention?
Thoracentesis to remove fluid
Child with croup has inspiratory stridor. What’s the priority?
Humidified oxygen + airway support
TB patient starting isoniazid reports numb hands. What do you give?
Vitamin B6
RSV infant with nasal congestion + retractions — first action?
Suction nose/mouth
Patient with empyema has fever + pus in pleural space. What’s needed?
Chest tube drainage
Post‑thoracentesis patient suddenly has absent breath sounds. What’s happening?
Pneumothorax
Child with tracheoesophageal fistula has abdominal distention. Why?
Air entering stomach through fistula
CF patient with recurrent infections — priority teaching?
Airway clearance (CPT, mucolytics)
Patient with pulmonary edema has crackles + pink frothy sputum. First action?
High‑Fowler’s + oxygen
Patient with pneumonia has fever + productive cough. What confirms diagnosis?
Chest X‑ray
Patient with suspected TB — what isolation?
Airborne (N95, negative pressure)
Patient with DKA has fruity breath + dehydration. What’s the FIRST priority?
IV fluids
Patient with metabolic acidosis from DKA — what compensatory sign?
Kussmaul respirations
COPD patient on bronchodilators still wheezing — next step?
Add corticosteroids
Main causes of hyponatremia?
Diuretics, GI suction, diarrhea, vomiting, excess water, SIADH.
Key symptoms of hyponatremia?
SALT LOSS: lethargy, confusion, seizures, limp muscles.
Main causes of hypernatremia?
Water loss, fever, sweating, diarrhea, diabetes insipidus.
Symptoms of hypernatremia?
YOU ARE FRIED: fever, restlessness, edema, ↓ urine.
Priority care for hypernatremia?
Give hypotonic fluids (0.45% NS), monitor neuro, restrict sodium