Barry BMS Histology COMP EXAM QUESTIONS WITH COMPLETE SOLUTION GUIDE (A+ GRADED 100% VERIFIED) LATEST VERSION 2025!!

All 3 types of collagen contain

a)a perichondrium

b)capillaries

c)Type II collagen fibrils

d)cells aligned in rows

e)isolated cells in lacunae

isolated cells in lacunae

The basement membrane

contains:

a)reticular fibers

b)Type III collagen fibrils

c)laminin

d)Type IV collagen fibrils

all the above

Bone grows in length by:

a)differentiation of

chondroblasts from the

perichondrium

b)interstitial growth of

osteoblasts inthe epiphyseal

plate

c)appositional growth of bone

from the periosteum

d)interstitial growth of

chondrocytes in the

epiphyseal plate

e)division of chondrocytes in

the periosteal collar

interstitial growth of osteoblast in the epiphyseal plate

Both mast cells and __________

secrete histamine

a)basophils

b)neutrophils

c)plasma cells

d)eosinophils

e)megakaryocytes

basophils

Capillaries should not be

present in

a)cardiac muscle

b)compact bone

c)pseudostratified epithelium

d)peripheral nerves

e)dense irregular connective

tissue

pseudo stratified epithelium

The cells that secrete

testosterone binding protein

are the:

sertoli cells

A cell that has a euchromatic nucleus

would most likely:

b)have few ribosomes in the cytoplasm

c)have poorly developed nucleolus

d)produce small amounts of proteins

e)be transcribing large amounts of its

genome

be transcribing large amounts of its genome

what forms the nail

nail matrix

The conductive airways contain:

a. basal cells

b. goblet cells

c. ciliated cells

d. seromucous glands

all of the above

Contraction of skeletal muscle begins with

the release of calcium into the cytoplasm.

Which structure stores and releases the

calcium?

a)RER

b)Golgi body

c)mitochondria

d)T-tubules

e)terminal cisternae

terminal citernae

The correct sequence of the sperm progresses from the testicle toward the urethra

straight tubes to rete testis

sperm pathway

seminiferous tubes to straight tubes to rete testis to efferent ducts to ductus epididymis to ductus (vas) deferens to seminal vesicles for addition of nourishing liquid (semen) to prostate gland for addition of neutral fluid to semen which protects sperm from acidic environment of vagina to Cowper's Gland to urethra

During child birth, the smooth muscle cells

of the uterus contract together in strong

waves because they are connected by

a)tight junctions

b)fascia adherens

c)gap junctions

d)intercalated discs

e)zonula occludens

gap junctions

Estrogen is secreted by the

theca externa

Fertilization generally occurs in

oviduct (fallopian tubes)

Fibrocartilage contains:

a)perichondrium

b)extensive capillary network

c)matrix with Type II collagen fibrils

d)cells in lacunae

e)all of the above

cells in lacunae

The filtration structures in the kidney

include all EXCEPT:

a. podocyte slits

b. basement membrane

c. macula densa

d. glomerulus

e. endothelial fenestrae

macula densa (which is an area of closely packed specialized cells lining the wall of the cortical thick ascending limb of the loop of Henle, at the transition to the distal convoluted tubule)

fovea centralis contains:

rods or cones?

cones

the functions of the ductus deferens

During ejaculation, the smooth muscle in the walls of the ductus (vas) deferens contracts reflexively, thus propelling the sperm forward, out of the epididymis; sperm is transferred from the vas deferens into the urethra, collecting secretions from the male accessory sex glands such as the seminal vesicles, prostate gland and the bulbourethral glands, which form the bulk of semen

the gall bladder is lined with

simple columnar epithelium

A gland is classified as "mixed" if it has

a)tubular and acinar secretory units

b)aprocrine and holocrine secreting

cells

c)serous and mucous cells

d)branched and unbranched ducts

e)endocrine and exocrine cel

serous and mucous cells

the hormone that causes the formation of the corpus lute is the

progesterone

immediately BEFORE the inhaled air enters a respiratory bronchiole the air is in what structure

terminal bronchiole

implantation and development of the fetus inside the uterus is called the ____ pregnancy

normal

An increase in cell size and organelles

in response to external stimuli is

defined as:

a)hypertrophy

b)hyperplasia

c)metastasis

d)necrosis

e)metaplasia

hypertrophy

In CROSS SECTION, cardiac muscle can be best differentiated from skeletal

muscle by the presence of:

a)intercalated discs

b)centrally located nuclei

c)acidophilic cytoplasm

d)myofibrils

e)striations

centrally located nuclei

The inner surface of the urinary bladder is lined with

transitional epithelium

In the epidermis the majority of keratohyalin granule containing cells are located

stratum granulosum

In the later stages of red blood cell development, the

a)nucleolus becomes larger and more visible

b)cell diameter increases

c)specific granules become visible

d)nucleus becomes smaller and more heterochromatic

e)nucleus become more lobulated

nucleus becomes smaller and more heterochromatic

In the liver, nutrients from blood enter the space of Disse through

sinusoidal wall

In the sublingual gland, the cell that secretes mucus into the oral cavity has a:

a)well developed rough ER

b)basophilic, grainy cytoplasm

c)cytoplasm filled with lysosomes

d)clear or lightly staining cytoplasm

e)round euchromatic nucleus

clear or lightly staining cytoplasm

In which type of epithelium are all the cells attached to the basal lamina?

a)stratified squamous epithelium,

keratinized

b)transitional epithelium

c)stratified squamous epithelium, nonkeratinized

d)stratified columnar epithelium

e)pseudostratified epithelium

pseudostratified epithelium

In which type of epithelium do the surface cells lack nuclei?

a)transitional epithelium

b)stratified squamous epithelium, keratinized

c)stratified squamous epithelium, nonkeratinized

d)stratified cuboidal epithelium

e)psuedostratified epithelium

stratified squamous epithelium, keratinized

The ________ is the predominant cell

within the epidermis, whereas the _____

predominates in the dermis

keratinocyte,

fibroblast

dermal macrophages are referred to as:

Langerhans cells

The large multi-nucleated cell lying against bone matrix is most likely

secreting _______ into the extracellular space

a)osteonectin and osteocalcin

b)acid

c)osteoid

d)calcium phosphate crystals

e)collagen fibers

acid

Loose connective tissue can contain:

a)large number of cells

b)very few cells

c)many capillaries

d)large amounts of ground substance

all of the above

Macrophages in the liver are referred to as:

Kupffer cells

The majority of secretory cells in the sublingual gland:

a)have a light, poorly stained cytoplasm

b)have a round, euchromatic nucleus

c)contain large amounts of smooth ER

d)have basophilic granules in the cytoplasm

e)secrete a water, protein rich secretion

have a light, poorly stained cytoplasm

The medullary rays contain all EXCEPT:

a. loop of henle

b. proximal straight tubule

c. papillary duct

d. distal straight tubule

e. collecting duct

papillary duct

Melanocytes produce what material in a membrane bound granule?

melanin

Menstruation is the result of an increase in

Contraction

of coiled

arteries

Mitochondria

a)are motile

b)stain with eosin

c)contain small amounts of DNA

d)consists of two unit membranes

all of the above

The oral cavity is lined by a stratified squamous epithelium. A biopsy of the

epithelium showed a disorganized arrangement and maturation of cells. The

shape and size of the cells was altered from

normal. Which term best describes this change?

a)dysplasia

b)hyperplasia

c)metastasis

d)metaplasia

e)hypertrophy

dysplasia

Osteoblasts can develop from cells located in the

a)marrow cavity

b)periosteum

c)Volkmann's canal

d)Haversian canal

all of the above

Osteoblasts have a basophilic cytoplasm

when stained with H&E. Which structure is

most responsible for this staining?

a)smooth ER

b)heterochromatin

c)rough ER

d)free or polyribosomes

e)mitochondria

rough ER

Osteoprogenitor cells are present in the

a)periosteum

b)Volkmann's canals

c)endosteum

d)Haversian canals

all of the above

Oxygenated blood will be in this vessel before entering the liver

hepatic artery

The pancreas contains:

a)demilunes

b)striated ducts

c)fenestrated capillaries

d)mucous cells

e)all of the above

fenestrated capillaries

The penile urethra is surrounded by

corpus spongiosum

The portal triad contains branches of all EXCEPT:

a. portal vein

b. hepatic vein

c. bile duct

d. hepatic artery

e. lymphatics

hepatic vein

The prostate gland has:

a. corpora amylacea

b. thick fibrolactic capsule

c. many small glands

d. smooth muscle in the stroma

e. all of the above

all of the above

The 'red eye' on flash photography is the result of dialated pupil showing the dense vascular network of the

retina

The renal corpuscle contains all EXCEPT

a. glomerular endothelium

b. parietal layer of bowmans capsule

c. basement membrane

d. visceral layer of bowman's capsule

e. macula densa

macula densa

The renal corpuscle does NOT contain

vasa recta

The sebaceous gland usually empties into the _____

hair follicle

Select the best match of epithelium and function

a)simple columnar epithelium - ion exchange

b)transitional epithelium — secretion

c)stratified squamous epithelium - movement of gases and solutes

d)simple cuboidal epithelium - absorption

e)pseudostratified epithelium - protection

simple cuboidal epithelium - absorption

what is the function and location of simple cuboidal epithelium

Function: secretion and absorption

Location: Kidney tubules; ducts and secretory portions of small glands, ovary surface.

what is the function and location of simple columnar epithelium

Function: Absorption; secretion; ciliated type propels mucus (or reproductive cells) by ciliated action.

Location: nonciliated type lines most of the digestive tract (stomach to anal canal), gallbladder and excretory ducts of some glands; ciliated variety lines small bronchi, uterine tubes, and some regions of the uterus.

what is the function and location of transitional epithelium

function: stretches readily and permits distension of urinary organ by contained urine

Location: lines the ureters, urinary bladder, and part of the urethra

what is the function and location of stratified squamous epithelium

Function: protects underlying tissues in areas subject to abrasion

Location: nonkeratinized type forms the moist lining of the esophagus, mouth, and vagina; keratinized type forms the epidermis of the skin, a dry membrane.

what is the function and location of psuedostratified epithelium

Function: Secretion, particularly of mucus; propulsion of mucus bu ciliary action.

Location: nonciliated type in male's sperm-carrying ducts and ducts of large glands; ciliated variety lines the trachea, most of the upper respiratory tract.

what is the function and locations of simple squamous epithelium

function: Allows passage of materials by diffusion and filtration in sites where protection is not important; secretes lubricating substances in serosae.

location: Kidney glomeruli, air sacs of lungs, lining of heart, blood vessels, and lymphatic vessels; lining of ventral body cavity(serosae)

what is the function and location of stratified cuboidal epithelium

Function: protection

Location: Largest ducts of sweat glands, mammary glands, and salivary glands.

what is the function and location of stratified columnar epithelium

Function: protection and secretion

Location: rare in the body; small amounts in male urethra and in large ducts of some glands

Select the BEST match of phase and cell

activity:

a)M phase - duplication of chromosome

b)S-secretion of proteins

c)G1-DNA syntheis

d)G0-sister chromatids separate

e)G2-assembly of mitotic spindle

G2-assembly of mitotic spindle

Serous cells:

a)contain large amounts of smooth ER

b)have acidophilic cytoplasm

c)have a round, euchromatic nucleus

d)have a poorly developed nucleolus

e)produce a thick, viscous glycoprotein

rich secretion

C.) have a round, euchromatic nucleus

Serous cells are found in the:

a)mammary gland

b)pancreas

c)adrenal gland

d)parathyroid gland

e)all of the above

pancreas

Spermiogenesis is the

transformation

of a spermatid to

a sperm

Stimulus for the completion of the second meiotic division of the egg is

fertilization

Stria vascularis is found in the

cochlear duct

The submandibular gland is classified as a compound gland because it has:

a)tubular and aveolar shaped secretory

units

b)ducts that branch

c)exocrine and endocrine cells

d)merocrine and holocrine cells

e)mucous and serous cells

ducts that branch

The submandibular gland is classified as:

a)mixed gland

b)simple gland

c)apocrine gland

d)endocrine gland

e) all of the above

mixed gland

The testicular cells that form the blood testes barrier are the

sertoli cells

The tissue best describing the lamina propria:

loos connective tissue

To enter the blood, in the air/blood barrier, oxygen passes from the type I cell directly into the

capillary lumen

Trabecular or cancellous bone contains

a)interstitial lamellae

b)Haversian canals

c)Volkmann's canal

d)canalicula

e)all of the abov

canalicula

Unlike compact bone, spongy bone lacks:

a)collagen fibers

b)endosteum

c)cells linked by canaliculi

d)matrix arranged into lamellae

e)osteons

osteons

The vagina is lined by a thick protective epithelium. Which junction would keep the cells strongly attached to each other?

a)zonula adherens

b)gap junction

c)intermediate junction

d)desmosome

e)zonula occludens

desmosome

The visceral peritoneum of the surface of the urethra is called

Perimetrium

What is the main criterion for the classification of loose connective tissue?

a)wide variety of cells present

b)small number of fibers in the matrix

c)many capillaries

d)disorganized arrangement of fibers

e)large number of cells

small number of fibers in the matrix

What nourishes the lactobacillus microflora in the female reproductive system?

Glycogen in

the vaginal

epithelium

Which cell can replicate?

a)cardiac muscle cell

b)osteoblast

c)fibroblast

d)skeletal muscle fiber

fibroblast

Which cell contains the most lysosomes?

a)macrophage

b)megakaryocyte

c)osteocyte

d)monocyte

e)basophil

macrophage

Which cell is attached to the surrounding connective tissue by a basal lamina?

a)cementocyte

b)osteocyte

c)macrophage

d)adipocyte

e)fibroblast

adipocyte

Which cell produces surfactant?

type II pneumocyte

Which cells are the major secretory cells in the liver?

Hepatocytes

Which developing cell has slightly indented nucleus and faint, azurophilic granules in its cytoplasm?

a)basophilic erythroblast

b)basophilic myelocyte

c)monocyte

d)eosinophilic band

e)neutrophilic metamyelocyte

neutrophilic metamyelocyte

Which epidermal layer is characterized by cells that are linked by monofilaments

stratus spinosum

Which is not derived from monocytes?

a)osteocytes

b)foreign body giant cells

c)Kupffer cells

d)macrophages

e)microglia

osteocytes

Which junction would completely block the passage of molecules between neighboring epithelial cells?

a)zonula occludens

b)macula adherens

c)intermediate junction

d)gap junction

e)zonula adherens

zonula occludens

Which migrating cell in the connective tissue has acidophilic granules and a

bilobed nucleus?

a)mast cell

b)plasma cell

c)eosinophil

d)macrophage

e)neutrophil

eosinophil

Which of the eye structures secretes the aqueous humor

ciliary body

Which of the following epithelia would best allow the movement of gases and small molecules from the lumen into the underlying connective tissue?

b)simple columnar epithelium

c)pseudostratified epithelium

d)stratified squamous epithelium

e)simple squamous epithelium

simple squamous epithelium

What is the juxtaglomerular apparatus?

formed by the distal convoluted tubule and the glomerular afferent arteriole. It is located near the vascular pole of the glomerulus and its main function is to regulate blood pressure and the filtration rate of the glomerulus.

Which of the following is present in both intramembranous and

endochondral ossification?

a)mesenchyme

b)perichondrium

c)epiphyseal plate

d)periosteal bone collar

e)cartilage mode

mesenchyme

Which of the following is the layer of the retina closest to the choroid?

Simple cuboidal pigmented epithelium

Which of the following regions of the nephron is MOST likely to be found in the renal medulla?

Loop of Henle

Which of the following statements describes the histology of the ureter

Contatins a mucosa, and muscularis layers

Which of the following structures in the lungs has a ciliated epithelium and cartilage?

Bronchus