anti ulcer, gout., asthma, nsaid

• H2 Blockers

• PPIs

• Antacids

• Sucralfate

• Bismuth

• Misoprostol

What are the anti ulcer drugs

• Cimetidine (Tagamet)

• Ranitidine (Zantac)

• Famotidine (Pepsid AC)

• Nizatidine (Axid)

What are the H2 Blockers

Antacids

This drug class is used to neutralize stomach acid for quick relief

• Bismuth subsalicylate

• Tetracycline

• Metronidazole

Components of Helidac

Nabumetone

All NSAIDs are acidic except

• Propionic acid derivatives

• Pyrrolealkanoic acid dervivative

• Phenylaanoic acid derivatives

• Indole derivative

• Pyrazolone derivative

• Phenylacetic acid derivative

• Fenamate

• Oxicam

• Naphthylacetic acid derivative

• Salicylate

NSAIDs classifications

Ibuprofen

NSAID with the shortest half life and tolerable side effects

• Ibuprofen

• Ketoprofen

• Naproxen

Propionic acid derivatives

Tolmetin

Pyrrolealkanoic acid derivative

Flubiprofen

Phenylalkanoic acid derivative

Indomethacin

Indole derivative

Indomethacin

NSAID that is also used for gout and PDA as an anti inflammatory

Phenylbutazone

• Pyrazolone derivative

• Withdrawn; causes aplastic anemia

Diclofenac

Phenylacetic acid

Meclofenamate

Fenamate

• Mefenamic acid

• Meclofenamate

Oxicam (enolic acid)

Nabumetone

Napthyhlacetic acid produrg

• Aspirin

• Diflunisal

• Salsalate

Salicylate

• Anti inflammatory

• Analgesic

• Anti pyretic

• Anti thrombotic

What are the 4As of ASA

Reye's syndrome

ASA SE when ad to <16 year olds

• Allopurinol/Febuxostat (XO inhibitor)

• Colchicine (Microtubule inhibitor)

• Oxaprozin (DMARD)

• Indomethacin (NSAID)

• Uricosuric agents (Probenecid, Sulfinpyrazone, Pegloticase)

Drugs used for Gout

• Allopurinol

• Febuxostat

Identify the XO Inhibitor

• Purine analog

• Non purine analog

• Albuteorl

• Levalbuterol

SABA

• Arformoterol

• Formoteol

• Indacaterol

• Salemterol

• Olodaterol

LABA

• Betamethasone

• Budesonide

• Ciclesonide

• Fluticasone

• Mometasone

• Triamcinolone

ICS

• Formoterol/Budesonide

• Formoterol/mometasone

• Salmeterol/Fluticasone

• Vilanterol/Fluticasone

LABA/ICS

• Ipratropium

SA Anticholinergic

• Aclidinium

• Tiotropium

• Umeclidinium

• Glycopyrrolate

LA Anticholinergic

• Bronchodilators

• Anti inflammatory agents

• Mast cell stabilizers

Anti asthma drugs classifications

• B2 agonists

• Methylxanthines

• Anticholinergics

bronchodilators

• Theophylline

• Theobromine

• Caffeine

• 1,3 dimethylxanthine -

• 3,7 dimethylxanthine -

• 1,3,7, trimethylxanthine

• Leukotriene modifiers (Zileuton 5lox inhibitor, zafir/montelukast lt inhibitors)

• Corticosteroids (glucocorticoids)

Anti inflammatory agents (anti asthma drugs)

• Nedocromil

• Cromolyn

Mast cell stabilizers