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What are the 6 bacterial skin infections?
Acne
Dermatitis(psuedomonas)
impetigo, folliculitis, cellulitis, necrotizing fascitis( staph aureous, group A strep)
MRSA skin infections
toxemias caused by staph aureus (SSS and TSS)
cutaneous anthrax
What bacteria causes acne?
Proprionibacterium acne
what are the key identifiers of acne
Teenagers▪
Pustule▪
Opportunistic pathogen (normal flora that overgrows)
what disease does Pseudomonas aeruginosa cause
dermatitis(hot tub rash)
otitis externa(swimmers ear)
burn wound infections
what are key identifiers of Pseudomonas aeruginosa
Green
Naturally resistant to antibiotics
In soil/water
what are the diseases of Staphylococcus aureus
Skin (impetigo, folliculitis, cellulitis, necrotizing fasciitis)
Sepsis
Upper respiratory infections
Toxic shock syndrome (toxemia)
Scalded skin syndrome (toxemia)
what are the key identifiers of Staphylococcus aureus
THINK MRSA (if it's staph aureus, it might be about MRSA)
CA vs HA MRSA: look for PVL gene or susceptibilities1)
Catalase +
Normal flora
Protein A
TSST-1 (toxic shock syndrome)
Exfoliative toxin (scalded skin syndrome)
what are the diseases for Streptococcus pyogenes (group A strep GAS)
Skin (impetigo, folliculitis, cellulitis, necrotizing fasciitis)
Sepsis
Strep throat (pharyngitis)
Rheumatic fever (autoimmune)
Scarlet fever (toxemia)
what are the key indicators of Streptococcus pyogenes (group A strep GAS)
Catalase -
M protein (rheumatic fever)
SPE A and SLO
Erythrogenic toxin
MUST treat with antibiotics to prevent rheumatic fever
what disease does Bacillus anthracis
cutaneous anthrax
what are the key identifiers of Bacillus anthracis
Endospores
Black lesions
Bioterrorism
What are the 8 viral infection?
Measles
2. Rubella
3. Roseola
4. Chickenpox/shingles
5. Fifth Disease
6. Cold sores and skin herpes
7. Hand, foot, and mouth disease
8. Warts
which viral infections are exanthems?
1. Measles
2. Rubella
3. Roseola
4. Chickenpox/shingles
5. Fifth Disease
what disease does measles virus cause
Measles
Immune amnesia
Subacute sclerosing panencephalitis (SSPE)
what are the key identifiers of the measles virus
Exanthem
Koplik spots
Very contagious
what diseases does rubella virus cause
Rubella (German measles)
Congenital rubella syndrome (birth defects)
what are key indicators of rubella virus
Exanthem
Pregnancy
what are the diseases of Human herpesvirus 6 (HHV-6)
roseola
what are the key indicators of Human herpesvirus 6 (HHV-6)
Exanthem
Common, mild, no big deal
what are the diseases of Varicella-zoster virus
Chickenpox (varicella)
Shingles (Zoster)
what are the key indicators for Varicella-zoster virus
Exanthem
Latency
Spread of shingles vs chickenpox
what are the diseases of parovirus B19
fifth disease
what are the key indicators of parovirus B19
Exanthem
Slapped cheek rash
what are the diseases of HSV-1
Cold sores
Cutaneous herpes
Keratitis
Encephalitis
what are the key identifiers of HSV-1
Latency
Vesicular rash
what are the diseases of Coxsackievirus 16
Hand, Foot, and Mouth Disease (HFMD)
what are the key indicators of Coxsackievirus 16
Children, daycare
Enterovirus
what disease does Human Papillomavirus (HPV) cause
warts
what are the key indicators of Human Papillomavirus (HPV)
Rough papules
what are the two fungal skin diseases
1. Ringworm (Tinea)
2. Candidiasis
what disease does Dermatophytes cause
Ringworm
Athlete's foot
Jock itch
Other tinea
what are key indicators of Dermatophytes
Fungi on skin
what disease does Candida albicans cause
Candidiasis (yeast infections)
what are the key identifiers of Candida albicans
Immunocompromised or AIDS
After antibiotic use
what are the 4 parasitic infections of the skin?
1. Leishmaniasis
2. Hookworm
3. Scabies
4. Lice
which 2 parasitic infections are technically caused by insects
3. Scabies
4. Lice
what disease does Leishmania sp. cause
Leishmaniasis
what are the key indicators of Leishmania sp.
Protozoa
Spread by vector
Volcanic ulcers
what disease does Helminth (Ancylostoma duodenale) cause
Hookworm
what are the key indicators of Helminth (Ancylostoma duodenale)
Barefoot/contaminated soil
Southern U.S.
what disease does Mites (Sarcoptes scabiei) cause
scabies
what are the key indicators of Mites (Sarcoptes scabiei)
Insects
Eggs laid under skin
what disease does Lice (pediculus humanus capitis) cause
lice
what are the key identifiers of Lice (pediculus humanus capitis)
Itchy scalp
Insects
Resistance to insecticides
what are the 5 disease of the eye
1. Conjunctivitis (pink eye)
2. Ophthalmia neonatorum
3. Trachoma
4. Keratitis
5. Ocular histoplasmosis
what is the microbial cause of conjunctivitis
Bacterial
Viral
what are the key indicators of conjunctivitis
Clear or purulent discharge
what are the microbial causes of Ophthalmia neonatorum (newborn conjunctivitis)
Bacteria: Neisseria gonorrhoeae
Bacteria: Chlamydia trachomatis
what are the key indicators of Ophthalmia neonatorum (newborn conjunctivitis)
Infected during vaginal delivery
Mother has STI
Eyedrops for newborns
what is the microbial cause for trachoma
Bacteria: Chlamydia trachomatis
what are the key indicators of trachoma
infection of conjunctiva, but damage to cornea
Blindness
Obligate intracellular bacteria
what are is the microbial cause of Keratitis
Virus: HSV-1 (cause of encephalitis, skin infections)
what are the key indicators of keratitis
Latency
Cornea infection
what is the microbial cause of Ocular histoplasmosis
Fungal: Histoplasmosis capsulatum (also seen in AIDS related complex)
what are the key indicators of Ocular histoplasmosis
Immunocompromised
Contaminated soil
Blindness
what are the three diseases of the ears
1. Otitis externa (swimmer’s ear)
2. Otitis media (ear infection)
3. Otitis interna (labyrinthitis)
what is the microbial cause of Otitis externa (Swimmer's ear)
Bacteria: Pseudomonas aeruginosa (also seen in dermatitis, burn wounds)
Fungal: Aspergillus
Viral
what are the key indicators of Otitis externa (Swimmer's ear)
Outer ear
Itchy, red
what is the microbial cause of Otitis media (ear infection)
Bacterial: Streptococcus pneumoniae (also in meningitis)
Bacterial: Haemophilus influenzae (also in meningitis)
what are the key indicators of Otitis media (ear infection)
Associated with respiratory infections
Eustachian tubes and middle ear
Pressure in ear
what is the microbial cause for Otitis Interna (labyrinthitis)
virus
what are the key indicators for Otitis Interna (labyrinthitis)
Dizziness, vertigo
Inner ear
what are the 3 diseases of wounds
1. Burn wound infections
2. Surgical site infections
3. Gas gangrene
what is the microbial cause for burn wound infections
Bacteria: Pseudomonas aeruginosa (also in dermatitis, outer ear infection)
what are the key indicators of burn wound infections
Green
Burn wound
what is the micorbial cause for Surgical site infections (SSIs)
Patient's normal flora!
what is the key indicator for Surgical site infections (SSIs)
Infection/inflammation after surgery
what is the microbial cause of gas gangrene
Bacteria: Clostridium perfringens
what are the key indicators of gas gangrene
Deep tissue wound
Gas buildup in tissues
Diabetes
Reduced blood flow
what are the 6 cardio/lymph diseases
1. Bacteremia
2. Lymphangitis
3. Septicemia (sepsis)
4. Severe sepsis
5. Septic shock
6. Endocarditis
what are the diseases of Staphylococcus aureus
Sepsis
Endocarditis
Skin infections
Toxemias
what are the key indicators of Staphylococcus aureus
THINK MRSA (if it's staph aureus, it might be about MRSA)
CA vs HA MRSA: look for PVL gene or susceptibilities1)
Catalase +
Normal flora
Protein A
what are the diseases Staphylococcus epidermidis causes
Sepsis
what are the key indicators of Staphylococcus epidermidis
Normal flora
IVs and catheters
what are the diseases Viridans streptococci cause
endocarditis
what are the key indicators of Viridans streptococci
Dental work
Normal flora
what are the diseases of Enterococcus sp
Sepsis
Endocarditis
what are the key indicators of Enterococcus sp
Prosthetic heart valves
Normal gut flora
what are the diseases of Streptococcus pyogenes (GAS)
Sepsis
Skin (cellulitis, necrotizing fasciitis)
Upper respiratory infections
Toxemias
what are the key indicators of Streptococcus pyogenes (GAS)
Catalase -
M protein (rheumatic fever)
Must treat with antibiotics
Rheumatic fever (a predisposition for endocarditis!!!)
Lemierre's syndrome
what are the diseases of Streptococcus agalactiae (Group B strep)
Sepsis (newborns)
Neonatal meningitis
what are the key indicators of Streptococcus agalactiae (Group B strep)
Catalase -
Newborns
Vaginal birth
Mother is infected
what are the diseases of Yersinia pestis
Plague
Sepsis
what are the key indicators of Yersinia pestis
Zoonotic
Vector (fleas)
what are the diseases of Brucella sp
Brucellosis
Sepsis
what are the key indicators of Brucella sp
Zoonotic
Food infection (meat and dairy processing)
Farmers and vets
what are the diseases of Francisella tularensis
Tularemia
Sepsis
what are the key indicators of Francisella tularensis
Rabbits
Inhaling aerosols
Landscapers and vets
what are the diseases of Borrelia burgdorferi
Lyme disease
Sepsis
what are the key indicators of Borrelia burgdorferi
Zoonotic
Vector: ticks
Bullseye rash
what are the diseases of Rickettsia ricketsii
Rocky mountain spotted fever
Sepsis
what are the key indicators of Rickettsia ricketsii
Zoonotic
Vector: ticks
Socks and gloves rash
what are the bacterial cardio and lymph diseases
1. Staphylococcus aureus
2. Staphylococcus epidermidis
3. Viridans streptococci
4. Enterococcus sp.
5. Streptococcus pyogenes
6. Streptococcus agalactiae
7. Endotoxic shock
• Gram-negative
• Gram-positive
what are the zoonotic bacterial diseases of the cardio/lymph system
8. Plague
9. Brucellosis
10.Tularemia
11. Lyme disease
12.Rocky Mountain
Spotted Fever
what are the viral diseases of the cardio/lymph system
1. Infectious mononucleosis
• Burkitt’s lymphoma
2. Hemorrhagic fever
3. Acute retroviral syndrome and AIDS
what diseases are from Epstein-Barr virus (EBV)
Mononucleosis (mono)
Burkitt lymphoma
what are the key indicators of Epstein-Barr virus (EBV)
Infects B cells and makes them atypical
Monospot test
Young adults/teens
what are the microbial cause of hemorrhagic fever
Ebola virus
Yellow fever virus
Dengue virus
what are the key indicators of hemorrhagic fever
Patients blood vessels are leaking
U.S. citizen went on vacation
Mosquito vector
what are the diseases of Human immunodeficiency virus (HIV)
Acute retroviral syndrome
Acquired immunodeficiency syndrome (AIDS)
AIDS-related complex