Gestational Trophoblastic Disease

hydatiform mole

presence chorionic villi

types hydatiform moles

• complete (abnormal chorionic villi) or partial (abnormal villi + fetal tissue) (benign)

• invasive (malignant)

non-molar trophopblastic neoplasms - types

• choriocarcinoma

• placental site trophoblastic tumour

• epitheliod trophoblastic tumour

symptoms hydatiform mole

1-2 months amenorrhea

vaginal bleed

ovarian theca-lutein cysts

increased fT4, decreased TSH

pre/eclampsia

dg hydatiform mole

increased b HCG

US

management hydatiform mole

molar evacuation by suction curettage

blood banking support

monitoring hcg levels

________ are clinically characterized by their aggressive invasion into the myometrium and propensity to metastasize

gestational trophoblastic neoplasia

gestational trophoblastic neoplasia always develop after what

pregnancy (molar/abortion/ectopic/normal delivery)

clinical gestational trophoblastic neoplasia

irregular bleeding

uterine subinvolution

Unusually persistent bleeding after any type of pregnancy should prompt what

bhcg level measurement

dg curettage

ttt gestational trophoblastic neoplasia

MTX if low risk

high risk - combo chemo (EMA-CO)