Check Your Understanding- Ch. 10, 11, 13, 14, 15

For quiz 2

When systemic vascular resistance is decreased, blood flow \n a. moves to the extremities \n b. increases \n c. stays the same \n d. decreases

decreases

The anemia resulting from a deficiency of either Vitamin B12 (cobalamin) or folate is caused by a disruption in DNA synthesis of the blast cells in the bone marrow that produces very large abnormal marrow cells called megaloblasts. \n a. true \n b. false

a. true

RhoGAM (an Rh antibody) would be appropriate in an Rh-___________ woman with an Rh-___________ antibody titer carrying an Rh-__________ fetus. \n a. negative, negative; positive \n b. negative; negative; negative \n c. positive; negative; negative \n d. negative; positive; positive

a. negative; negative; positive

Patients who experience anemic episodes when exposed to certain drugs most like have \n a. sickle cell anemia \n b. glucose-6-phosphate dehydrogenase deficiency \n c. thalassemia \n d. spherocytosis

b. glucose-6-phosphate dehydrogenase deficiency

The patient is a 12-year-old boy diagnosed with acute lymphoid leukemia (ALL). As part of treatment, the patient must undergo several weeks of chemotherapy. The most serious complication of chemotherapy is \n a. alopecia \n b. vomiting \n c. infection \n d. anemia

c. infection

A diagnostic laboratory finding in myeloma is \n a. Bence Jones proteins in the urine. \n b. elevated blood glucose levels. \n c. increased IgM antibody titer. \n d. decreased platelet count.

a. Bence Jones proteins in the urine

When a patient is struck in the eye by a baseball, the result is redness and swelling. This increase in blood flow to a localized area is called. \n a. edema \n b. autoregulation \n c. hyperemia \n d. hypoxia

c. hyperemia

Severe combined immunodeficiency (SCID) syndrome is an example of a(n) \n a. primary acquired immunodeficiency \n b. hypersensitivity reaction \n c. deficient immune response \n d. excessive immune response

c. deficient immune response

The effects of histamine release include \n a. bronchodilation \n b. increased vascular permeability. \n c. decreased gut permeability. \n d. vasoconstriction.

b. increased vascular permeability.

The cause of the most common form of anemia is \n a. protein malnutrition. \n b. iron deficiency. \n c. acute bleeding. \n d. chronic disease.

b. iron deficiency.

The conversion of plasminogen to plasmin results in \n a. clot retraction. \n b. platelet aggregation. \n c. fibrinolysis \n d. activation of thrombin

c. fibrinolysis.

An important mediator of a type I hypersensitivity reaction is \n a. complement. \n b. histamine. \n c. T cells. \n d. antigen-antibody immune complexes.

b. histamine.

A serious complication of deep vein thrombosis is \n a. pulmonary embolus. \n b. stroke. \n c. hypertensive crisis. \n d. extremity necrosis.

a. pulmonary embolus.

A low mean corpuscular hemoglobin concentration (MCHC) and mean corpuscular volume (MCV) are characteristic of which type of anemia? \n a. Erythropoietin deficiency \n b. Vitamin B12 deficiency \n c. Iron deficiency \n d. Folate deficiency

c. Iron deficiency

Thalassemia may be confused with iron-deficiency anemia, because they are both \n a. microcytic. \n b. hyperchronic. \n c. genetic. \n d. responsive to iron therapy.

a. microcytic.

The prothrombin time (PT) and INR (international normalized ratio) measure the integrity of \n a. intrinsic pathway. \n b. extrinsic pathway. \n c. fibrinolysis. \n d. platelet function.

b. extrinsic pathway.

An increase in hemoglobin affinity for oxygen occurs with \n a. hyperthermia. \n b. elevated PCO2. \n c. shift to the left. \n d. shift to the right.

c. shift to the left.

Myasthenia gravis is a type II hypersensitivity disorder that involves \n a. symptoms of hyperthyroidism. \n b. impaired muscle function. \n c. symptoms of glomerular disease. \n d. symptoms of arthritis or polyarthralgia.

b. impaired muscle function.

A 5-year-old patient's parents report loss of appetite and fatigue in their child. The parents also state that the child refuses to walk as a result of pain. The child's most likely diagnosis is \n a. CML (chronic myeloid leukemia) \n b. ALL (acute lymphoid leukemia) \n c. AML (acute myeloid leukemia) \n d. CLL (chronic lymphoid leukemia)

b. ALL (acute lymphoid leukemia)

Blood flow throughout the periphery is regulated by \n a. hemodynamics. \n b. velocity. \n c. cardiac output. \n d. the autonomic nervous system.

d. the autonomic nervous system.

Which characteristic is indicative of hemolytic anemia? \n a. increased heart rate \n b. increased total iron-binding capacity \n c. jaundice \n d. hypovolemia

c. jaundice

A cause of thrombocytopenia includes \n a. chemotherapy. \n b. reduced erythropoietin. \n c. secondary polycythemia. \n d. hypoxemia.

a. chemotherapy

The principle Ig mediator of type I hypersensitivity reactions is \n a. IgA \n b. IgM \n c. IgE \n d. IgG

c. IgE

What is the correct definition of complete remission (CR) of leukemia? \n a. CR is less than 5% leukemic cells in the blood. \n b. CR is the absence of leukemic cells in the blood. \n c CR is less than 5% blasts in marrow and normal CBC values. \n d. CR is absence of leukemic cells regardless of CBC values.

c. CR is less than 5% blasts in marrow and normal CBC values.

Widespread activation of the clotting cascade secondary to massive trauma is called \n a. idiopathic thrombocytopenia purpura.  \n b. disseminated intravascular coagulation (DIC). \n c. hemophilia B. \n d. Hageman disease

b. disseminated intravascular coagulation (DIC).

Red blood cells obtain nearly all their energy from metabolism of \n a. acetyl coenzyme A. \n b. glucose. \n c. fats. \n d. proteins.

b. glucose

A commonly ingested substance associated with prolongation of the bleeding time is \n a. caffeine. \n b. tobacco. \n c. acetaminophen. \n d. aspirin.

d. aspirin

The goal of long term heparin for the management of a deep vein thrombosis is to \n a. prevent further clot formation. \n b. prevent clot dislodgement. \n c. dissolve the thrombus. \n d. relieve edema.

a. prevent further clot formation.

The major cause of death from leukemic disease is \n a. infection. \n b. kidney failure. \n c. hypovolemic shock. \n d. malnutrition.

a. infection

Excessive red cell lysis can be detected by measuring serum \n a. methemaoglobin \n b. bilirubin. \n c. hemoglobin. \n d. erythropoietin.

b. bilirubin.

The primary source of erythropoietin is provided by the

a bone marrow

b kidney

c lung

d liver

b kidney

The activated partial thromboplastin time (aPTT) is a measure of the integrity of

a the extrinsic pathway.

b the intrinsic pathway.

c actor VIII synthesis.

d plasminogen.

b the intrinsic pathway.

Which causes vasoconstriction?

a Norepinephrine

b Calcium channel blocker

c Adrenergic antagonist

d Acetylcholine

a Norepinephrine

Which form of leukemia demonstrates the presence of the Philadelphia chromosome?

a ALL (acute lymphoid leukemia)

b CLL (chronic lymphoid leukemia)

c AML (acute myeloid leukemia)

d CML (chronic myeloid leukemia)

d CML (chronic myeloid leukemia)

The Philadelphia chromosome is a balanced chromosome translocation that forms a new gene called

a bcr-abl.

bRb.

c p53.

d ARA-C.

a bcr-abl.

When a patient is struck in the eye by a baseball. the result is redness and swelling. This increase in blood flow to a localized area is called

a autoregulation.

b edema.

c hyperemia.

d hypoxia.

c hyperemia.

The hypersensitivity reaction that does not involve antibody production is type

a I

b II

c III

d IV

d IV

Which is not a manifestation of acute arterial obstruction? \n a. Pain \n b. Pallor \n c. Purpura \n d. Pulselessness

c. Purpura

The most common primary immune deficiency that affects only B cells is

a DiGeorge.

b Bruton agammaglobulinemia.

c Wiskott-Aldrich.

d selèctive lgA.

d selèctive lgA.

What laboratory finding is usually found in aplastic anemia?

a Leukocytosis

b Thrombocythemia

c Neutrophilia

d Pancytopenia

d Pancytopenia