ANS-150 (E1/L1): Hematopoiesis

Bone marrow

A soft tissue inside the bone that produces blood cells

Pluripotent hematopoietic stem cell

Single population of bone marrow cells from which all blood cells are descended

Common Lymphoid Progenitor (CLP) -> ?

- B lymphocytes

- T lymphocytes

- NK cells

B-Cell

Create antibodies for isolating and destroying invading bacteria and viruses.

T-Cell

Cells created in the thymus that produce substances that attack infected cells in the body.

NK-Cell

Suppressing viruses and destroying tumor cells

Common Myeloid Progenitor (CMP) -> ?

- Megakaryocyte

- Erythrocyte

- Mast cell

- Myeloblast

Granulocyte/macrophage progenitor -> ?

- Neutrophil

- Eosinophil

- Basophil

Megakaryocyte/Erythrocyte Progenitor (MEP) -> ?

- Megakaryocyte

- Erythrocytes.

Megakaryocyte -> ?

Platelets

Erythoblast -> ?

Erythocyte

Lymph Nodes

Bean-shaped filters along lymphatic vessels cleanse lymph and activate T and B cells.

Unknown Precursor of Mast Cell -> ?

Mast cell

Monocyte -> ?

Macrophage

Immature dendritic cell

Mature dendritic cell

Effector cells

short-lived cells that take effect immediately against the antigen and any pathogens producing that antigen

B-cell -> ?

Plasma cell

Plasma cell

A white blood cell that produces a single type of antibody

T-cell ->

Activated T-cell

Activated T-cell

starts mitotic division, making clones of itself

NK-cell -> ?

Activated NK-cell

Activated NK-cell

NK cell attacks foreign cell due to empty inhibitory receptor and activatory receptor binding.